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Multi-disciplinary approach to investigate the molecular basis of G…
https://www.phar.cam.ac.uk/research/Ladds15 Jun 2024: Ladds. G. (2021) CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells. -
Dr Cathy Wilson | Department of Pharmacology
https://www.phar.cam.ac.uk/news/wilson15 Jun 2024: Her main area of research is to develop therapeutic strategies to either inhibit Myc driven transcription to develop new cancer therapies or enhance Myc driven transcription to stimulate endogenous tissue repair. -
Innovating Protein Technologies for Therapeutic and Vaccine Design |…
https://www.phar.cam.ac.uk/research/Howarth15 Jun 2024: Nature Nanotechnology. 2023 Mar;18(3):290-298. NeissLock provides an inducible protein anhydride for covalent targeting of endogenous proteins. -
Designer proteins to seek and destroy | Department of Pharmacology
https://www.phar.cam.ac.uk/news/BBSRC-funded-project15 Jun 2024: These will be adapted in two applications: First, the disruption of endogenous protein-protein interactions to control and direct cellular processes in which they are involved. -
Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/research/Irvine/pubs15 Jun 2024: 2010) Genomic tagging reveals a random association of endogenous PtdIns5P 4-kinases II and II and a partial nuclear localisation of the II isoform. ... Irvine. R.F. (2007) Genomic tagging of endogenous Type IIβ phosphatidylinositol 5-phosphate 4 -
Research | Department of Pharmacology
https://www.phar.cam.ac.uk/research/Howarth/research15 Jun 2024: We have developed a new class of binding proteins that form covalent bonds to endogenous protein targets. -
Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/research/Ladds/pub15 Jun 2024: M. & Ladds. G. (2021) CGRP, adrenomedullin and adrenomedullin 2 display endogenous GPCR agonist bias in primary human cardiovascular cells. ... 2020) Receptor component protein, an endogenous allosteric modulator of family B G protein coupled receptors. -
Research Interest | Department of Pharmacology
https://www.phar.cam.ac.uk/research/Ladds/research15 Jun 2024: We are also using new methods to aid in the de-orphanisation (identification of endogenous agonists) for olfactory receptors. -
Enterprise and Industry Collaboration | Department of Pharmacology
https://www.phar.cam.ac.uk/enterprise-and-industry-collaboration15 Jun 2024: mRNA cardiac regenerative therapeutic that drives endogenous healing. Contact us. Department of Pharmacology. -
Publications | Department of Pharmacology
https://www.phar.cam.ac.uk/research/lindon/pub15 Jun 2024: Cell density-dependent induction of endogenous myogenin (myf4) gene expression by Myf5.
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