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1 - 10 of 14 search results for endogenous retrovirus |u:laser.ceb.cam.ac.uk where 0 match all words and 14 match some words.
  1. Results that match 1 of 2 words

  2. Nanoscopic insights into seeding mechanisms and toxicity of…

    https://laser.ceb.cam.ac.uk/system/files/documents/pnas-pintosi-2016.pdf
    3D), demonstrates that endogenous AS is pref-erentially recruited to elongate exogenous seeds rather thanundergoing nucleation. ... We find that these aggregates have a reducedpropensity to seed endogenous AS relative to preformed ASseed fibrils.
  3. Super-resolution imaging of alpha-synuclein polymorphisms and their…

    https://laser.ceb.cam.ac.uk/system/files/documents/integrbiol-nugent-2017.pdf
    More-over, our results showed that exogenously added monomerleads to the induction of endogenous a-synuclein aggregationwithout the two moieties coming into close proximity. ... incubated for 24 h in a-synuclein-free medium and immunostained for
  4. and Gabriele S. Kaminski SchierleEva-Maria Mandelkow, Clemens F.…

    https://laser.ceb.cam.ac.uk/system/files/documents/jbc-michel-2013.pdf
    Crucially, the two-color assayrevealed the presence of both K18-647 and endogenous Tau in. ... The image displays K18-647 fibrils (red) thatare intertwined with endogenous Tau (green).
  5. Nanoscale imaging of neurotoxic proteins Clemens F. Kaminski,…

    https://laser.ceb.cam.ac.uk/system/files/documents/spie-kaminski-2014.pdf
    Intriguingly, the cell expunges fibrillar aggregates that contain both the ingested K18Tau, shown in red, and endogenous wild type tau, already present in the cell, shown in green. ... F-1. Figure 5: Uptake of monomeric Tau protein into neuron-like cells
  6. Heparin acts as a structural component of β-endorphin…

    https://laser.ceb.cam.ac.uk/system/files/documents/chemcomm-nespovitaya-2016.pdf
    relevance of heparin-promoted amyloid models. The endogenous opiate b-endorphin is an essential neuropeptideinvolved in the stress response of higher organisms.1 In thesecretory pathway, it is temporarily stored in
  7. NPH-16016SSR 10..10 ++

    https://laser.ceb.cam.ac.uk/system/files/documents/pdf-neurophoton-kaminski-2016.pdf
    Fig. 6 Uptake of monomeric tau protein into neuron-like cells causes its aggregation and subsequentrecruitment of endogenous tau, normally present in the cell. ... Intriguingly, the cell expels fibrillaraggregates that contain both the ingested K18Tau,
  8. BMC BiologyBMC Biology This Provisional PDF corresponds to the ...

    https://laser.ceb.cam.ac.uk/system/files/documents/bmcbio-avezoz-2015.pdf
    When transfected into COS7 cells the fluorescent signal produced a typical ER pattern that colocalized with the endogenous ER chaperone BiP (Figure 2B). ... B) Immunoblot of endogenous PDI1A in the cells above, with tubulin serving as a loading control.
  9. A cancer-associated BRCA2 mutation reveals masked nuclear export…

    https://laser.ceb.cam.ac.uk/system/files/documents/jeyasekharan-nsmb-2013.pdf
    Red indicates DNA, cyan indicates BRCA2 (detected by anti-Flag) and purple indicates endogenous DSS1 (detected by anti-DSS1). ... a r t i c l e s. This mutant localized to the cytoplasm when expressed in DT40 cells lacking endogenous RAD51 (Fig.
  10. C-terminal calcium binding of α-synuclein modulates synaptic vesicle …

    https://laser.ceb.cam.ac.uk/system/files/documents/natcommLautenschlger2018.pdf
    3c). Next, we studied the behavior of endogenous alpha-synucleinin ventral midbrain (VM) neurons incubated with 100 µMdopamine. ... VM neurons treatedwith dopamine for 72 h were stained against endogenous alpha-synuclein and the synaptic vesicle protein
  11. OP-BRAI140256 1..7

    https://laser.ceb.cam.ac.uk/system/files/documents/brain-frischi-2014.pdf
    endogenous amyloid-b deposition in the hippocampus beginsto appear at 8–10 months of age.

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