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Publications | Coleman Laboratory
https://colemanlab.brc.cam.ac.uk/publications23 Feb 2024: 2020) Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors. ... 2010) Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons. Results that match 1 of 2 words
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New publication | Coleman Laboratory
https://colemanlab.brc.cam.ac.uk/news/gilley-paper23 Feb 2024: NMNAT2 is an endogenous axon maintenance factor that preserves axon health by blocking Wallerian-like axon degeneration. -
SARM1 activation and blocking | Coleman Laboratory
https://colemanlab.brc.cam.ac.uk/blog/sarm1-activation-and-blocking23 Feb 2024: An elevated NMN:NAD ratio favours SARM1 activation. A preprint from our collaborators in Italy reports that this holds at physiological levels of both metabolites, and that there are additional endogenous
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