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PPL number: | Granted: 13 Jan 20 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/molecular_and_genetic_regulation_of_glial_development_and_function_nts_redacted.pdf19 Aug 2021: Why is it important to undertake this work? As life expectancy increases, there are a growing number of brain diseases affecting people. -
PPL number: | Granted: 30 Jun 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/genes_and_mechanisms_involved_in_genome_regulation_nts_redacted.pdf13 Sep 2021: research, approaches and techniques regularly with scientists, animal technicians and Named People (in particular Animal Care and Welfare Officers and Veterinary Surgeons) within and outside the institute. -
PPL number: | Granted: 25 Jun 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_pathobiology_and_therapeutic_opportunities_of_ubiquitin_ligases_nts_redacted.pdf13 Sep 2021: Starting in adolescence, people with mutations in their FBXO7 gene develop a progressive parkinsonism which affects their coordination along with other symptoms. -
PPL number: | Granted: 19 Nov 19 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/breeding_of_transgenic_rodents_for_supply_of_tissues_to_the_client_nts_redacted.pdf20 Aug 2021: Who or what will benefit from these outputs, and how? Neurodegenerative disease affects millions of people and animals worldwide. -
PPL number: | Granted: 21 Jan 20 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/the_long-term_effects_of_developmental_hypoxia_on_cardiac_function_nts_redacted.pdf19 Aug 2021: womb. We hope to identify novel targets for drug intervention to protect people from developing cardiovascular diseases later in life. -
PPL number: | Granted: 06 Jul 21 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/the_role_of_the_immune_system_in_cardiovascular_disease_nts_expires2026_redacted.pdf13 Sep 2021: There are around 7.6 million people living with heart and circulatory diseases in the UK. -
PPL number: | Granted: 12 Nov 20 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/discovery_of_novel_compounds_for_the_treatment_of_dementia._nts_redacted.pdf19 Aug 2021: There are already approximately 50 million people worldwide with dementia, and as the general population ages, this has been predicted to increase to 150 million by 2050. -
PPL number: | Granted: 16 Apr 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_of_mental_health_nts_expires2023_redacted.pdf13 Sep 2021: Page 2 of 5. Our research aims to understand how and why mental health disorders occur, and to develop new treatments for people suffering from these disorders. -
PPL number: | Granted: 10 May 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/defining_the_role_of_the_senescent_cells_upon_the_cancer_and_pre-malignant_microenvironment_redacted.pdf18 Jun 2021: In addition, if we can develop new treatments for cancer, this will improve people's health-span: their length of healthy life. ... Of course, if people live into dependent old age this may increase societal costs later. -
PPL number: | Granted: 10 Jun 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_diseases_with_an_inflammatory_component_nts_expires2022_redacted.pdf13 Sep 2021: By studying early signs of the disease and developing preventative treatments for people at risk a real difference could be made to the prevalence of the disease and the suffering caused
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