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Post-translational modifications
https://www2.mrc-lmb.cam.ac.uk/ccsb/research/post-translational-modifications/This allowed us to test how H3K56 acetylation may control diverse phenomena by altering higher order chromatin structure; remodelling or repositioning nucleosomes; allowing nucleosome core particle ‘breathing’ or opening on DNA; ... To test this, -
Integral component of the Wnt enhancesome identified - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/integral-component-wnt-enhancesome-identified/16 Mar 2017: allowed him to test the functional relevance of these elements during fly development and in human cells.
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LMB 365 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-365/21 Jul 2023: During the last year, over 4,500 initial crystallisation screens were used at the LMB to test macromolecular samples of interest. ... This image for day 263 of #LMB365 shows a test spectrum created using precision sensors and software.
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RNA-seq course 2020 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-training/rna-seq-course-2020/21 Jul 2023: The second video is a PRAGUI practical that will take you through the process of running PRAGUI step-by-step with some test data.
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Publications
https://www2.mrc-lmb.cam.ac.uk/groups/rh15/Publications.html14 Apr 2021: Faruqi, A.R. Ultramicroscopy 107, 73-80 (2007). Digitisation of electron microscope films: six useful tests applied to three film scanners. -
New insight into how membrane proteins are made - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/new-insight-into-how-membrane-proteins-are-made/9 Nov 2018: synthesised in a test tube.
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Discovering how translation and mRNA decay are linked - MRC…
https://www2.mrc-lmb.cam.ac.uk/discovering-how-translation-and-mrna-decay-are-linked/21 Jun 2018: They then added them all to a test tube where they assembled into the complete active complex. ... Michael was then able to study the activity and regulation of Ccr4-Not in this test tube set-up.
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/18646
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/18646{"id":18646,"date":"2020-07-17T17:09:31","date_gmt":"2020-07-17T16:09:31","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=18646"},"modified":"2021-11-18T10:32:25","modified_gmt":"2021-11-18T10:32:25","slug":"putting-science-skills-to-new-use-du -
Scheres lab
https://www2.mrc-lmb.cam.ac.uk/groups/scheres/publications.html3 May 2024: Our publications. 2024. A. Burt, B. Toader, R. Warshmanage, A. von Kugelgen, E. Pyle, J. Zivanov, D. Kimanius, T.A.M. Bharat & S.H.W. Scheres (2024) "An image processing pipeline for electron cryo-tomography in RELION-5". bioRxiv 2024.04.26.591129. -
Work Experience - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/students/work-experience/10 Jun 2024: I particularly enjoyed learning about and examining Drosophila melanogaster, as well as learning about how they could be used to aid research and test out theories in the lab.
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Coot
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/21 Mar 2024: Yes - welcome. Crystallographic Object-Oriented Toolkit. Coot is for macromolecular model building, model completion and validation, particularly suitable for protein modelling using X-ray data. Coot displays maps and models and allows model -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20739
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20739{"id":20739,"date":"2021-07-29T11:20:57","date_gmt":"2021-07-29T10:20:57","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=20739"},"modified":"2021-07-29T11:20:57","modified_gmt":"2021-07-29T10:20:57","slug":"testing-the-capacity-for-intracellul -
How does the replisome respond to DNA damage? - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/how-does-the-replisome-respond-to-dna-damage/1 Jun 2018: Martin Taylor, from Joe’s group, recreated DNA replication in a test tube, using purified yeast replication proteins and yeast DNA templates.
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Index of /personal/pemsley/coot/files
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/coot-trial-adding-up-test.tar.gz. ... ligand-fitting-test-2-no-ligand.mtz. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/19083
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/19083{"id":19083,"date":"2020-09-03T11:49:53","date_gmt":"2020-09-03T10:49:53","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=19083"},"modified":"2023-07-21T12:49:55","modified_gmt":"2023-07-21T11:49:55","slug":"rna-seq-course-2020","status": -
Scheres lab
https://www2.mrc-lmb.cam.ac.uk/groups/scheres/structures.html7 Mar 2022: Our structures. Our methods aim to open up new experimental possibilities in Structural Biology studies. By ourselves or through collaborations, we have used our methods to determine new structures. Some of these structures are described here. For -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/810499
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/810499 -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/14619
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/14619{"id":14619,"date":"2019-07-03T10:47:14","date_gmt":"2019-07-03T09:47:56","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=14619"},"modified":"2023-07-21T12:49:43","modified_gmt":"2023-07-21T11:49:43","slug":"mesolens-microscopy-2009","sta -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/21995
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/21995{"id":21995,"date":"2022-01-05T11:54:57","date_gmt":"2022-01-05T11:54:21","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=21995"},"modified":"2022-01-05T12:18:56","modified_gmt":"2022-01-05T12:18:56","slug":"donald-caspar-1927-2021","stat -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20344
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20344{"id":20344,"date":"2021-04-20T11:59:40","date_gmt":"2021-04-20T10:59:40","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=20344"},"modified":"2021-05-05T09:58:45","modified_gmt":"2021-05-05T08:58:45","slug":"2021-max-perutz-lecture-to-be-given-
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