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Post-translational modifications
https://www2.mrc-lmb.cam.ac.uk/ccsb/research/post-translational-modifications/This allowed us to test how H3K56 acetylation may control diverse phenomena by altering higher order chromatin structure; remodelling or repositioning nucleosomes; allowing nucleosome core particle ‘breathing’ or opening on DNA; ... To test this, -
Schafer Lab Research
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/PublicEngagement_Lab_Page.html14 Oct 2019: Denise, Kristin and Eva have been taking part in this 8 week challenge project, introducing year 11 students to chemotaxis and helping them to design, test and present their own experiments. -
Integral component of the Wnt enhancesome identified - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/integral-component-wnt-enhancesome-identified/16 Mar 2017: allowed him to test the functional relevance of these elements during fly development and in human cells.
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LMB 365 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-365/21 Jul 2023: During the last year, over 4,500 initial crystallisation screens were used at the LMB to test macromolecular samples of interest. ... This image for day 263 of #LMB365 shows a test spectrum created using precision sensors and software.
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Publications
https://www2.mrc-lmb.cam.ac.uk/groups/rh15/Publications.html14 Apr 2021: Faruqi, A.R. Ultramicroscopy 107, 73-80 (2007). Digitisation of electron microscope films: six useful tests applied to three film scanners. -
RNA-seq course 2020 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/scientific-training/rna-seq-course-2020/21 Jul 2023: The second video is a PRAGUI practical that will take you through the process of running PRAGUI step-by-step with some test data.
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New insight into how membrane proteins are made - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/new-insight-into-how-membrane-proteins-are-made/9 Nov 2018: synthesised in a test tube.
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Discovering how translation and mRNA decay are linked - MRC…
https://www2.mrc-lmb.cam.ac.uk/discovering-how-translation-and-mrna-decay-are-linked/21 Jun 2018: They then added them all to a test tube where they assembled into the complete active complex. ... Michael was then able to study the activity and regulation of Ccr4-Not in this test tube set-up.
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Antiviral Bicycles are effective against SARS-CoV-2 - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/antiviral-bicycles-are-effective-against-sars-cov-2/16 Jun 2023: In order to turn the selected Bicycles into antivirals, Marina Vaysburd and Donna Mallery developed an assay to test for antiviral activity quickly and safely in the lab.
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https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/18646
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/18646{"id":18646,"date":"2020-07-17T17:09:31","date_gmt":"2020-07-17T16:09:31","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=18646"},"modified":"2021-11-18T10:32:25","modified_gmt":"2021-11-18T10:32:25","slug":"putting-science-skills-to-new-use-du -
Scheres lab
https://www2.mrc-lmb.cam.ac.uk/groups/scheres/publications.html3 May 2024: Our publications. 2024. A. Burt, B. Toader, R. Warshmanage, A. von Kugelgen, E. Pyle, J. Zivanov, D. Kimanius, T.A.M. Bharat & S.H.W. Scheres (2024) "An image processing pipeline for electron cryo-tomography in RELION-5". bioRxiv 2024.04.26.591129. -
Work Experience - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/students/work-experience/10 Jun 2024: I particularly enjoyed learning about and examining Drosophila melanogaster, as well as learning about how they could be used to aid research and test out theories in the lab.
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Coot
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/21 Mar 2024: Yes - welcome. Crystallographic Object-Oriented Toolkit. Coot is for macromolecular model building, model completion and validation, particularly suitable for protein modelling using X-ray data. Coot displays maps and models and allows model -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20739
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20739 -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/19083
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/19083{"id":19083,"date":"2020-09-03T11:49:53","date_gmt":"2020-09-03T10:49:53","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=19083"},"modified":"2023-07-21T12:49:55","modified_gmt":"2023-07-21T11:49:55","slug":"rna-seq-course-2020","status": -
Scheres lab
https://www2.mrc-lmb.cam.ac.uk/groups/scheres/structures.html7 Mar 2022: Our structures. Our methods aim to open up new experimental possibilities in Structural Biology studies. By ourselves or through collaborations, we have used our methods to determine new structures. Some of these structures are described here. For -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/14619
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/14619{"id":14619,"date":"2019-07-03T10:47:14","date_gmt":"2019-07-03T09:47:56","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=14619"},"modified":"2023-07-21T12:49:43","modified_gmt":"2023-07-21T11:49:43","slug":"mesolens-microscopy-2009","sta -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/21995
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/21995{"id":21995,"date":"2022-01-05T11:54:57","date_gmt":"2022-01-05T11:54:21","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?page_id=21995"},"modified":"2022-01-05T12:18:56","modified_gmt":"2022-01-05T12:18:56","slug":"donald-caspar-1927-2021","stat -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/5817
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/5817 -
Isothermal titration calorimetry to measure protein/peptide/lipid…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/techniqs/ITC.html26 Sep 2011: Isothermal Titration Calorimetry is used to make accurate measurements of affinities and stoichiometries of interactions. It is based on fine measurements of heat changes when ligands interact
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