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Scheres lab
https://www2.mrc-lmb.cam.ac.uk/groups/scheres/impact.html29 Nov 2023: Our impact. We are dedicated to advancing the field of cryo-EM structure determination. To help others in their structure determination efforts we make all our algorithm developments available through our open-source software package RELION. We are -
Scheres lab
https://www2.mrc-lmb.cam.ac.uk/groups/scheres/people.html30 Nov 2023: Our people. Dongqi Zhang. Post-doc. Dongqi studied Pharmaceutical Sciences at Shandong University, and she did a PhD in Structural Pharmacology at Zhejiang University. Dongqi joined our group as a postdoc in November 2023 to work on laboratory-based -
Scheres lab
https://www2.mrc-lmb.cam.ac.uk/groups/scheres/publications.html3 May 2024: Our publications. 2024. A. Burt, B. Toader, R. Warshmanage, A. von Kugelgen, E. Pyle, J. Zivanov, D. Kimanius, T.A.M. Bharat & S.H.W. Scheres (2024) "An image processing pipeline for electron cryo-tomography in RELION-5". bioRxiv 2024.04.26.591129. -
timeline | The Bacterial Cytoskeleton and other Molecular Machines
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/page12/index.html29 Apr 2024: In order to test whether the mode of DNA binding revealed by cryo-EM also occurs in cells, we genetically engineered E. -
Coot
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/21 Mar 2024: Yes - welcome. Crystallographic Object-Oriented Toolkit. Coot is for macromolecular model building, model completion and validation, particularly suitable for protein modelling using X-ray data. Coot displays maps and models and allows model -
LMB COVID-19 response - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/lmb-covid-19-response/22 Nov 2023: How can we test for, treat and prevent SARS-CoV-2 infection? Collaborators across the LMB have developed new models, assays, and screening platforms with the goal of investigating new methods ... and drugs that could be used to test for or treat COVID-19. -
Work Experience - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/students/work-experience/12 Feb 2024: I particularly enjoyed learning about and examining Drosophila melanogaster, as well as learning about how they could be used to aid research and test out theories in the lab. -
Buzz Baum - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/a-to-g/buzz-baum/22 Mar 2024: In doing so, we will put the “inside-out model” for the origin of the eukaryote cell to the test. -
Marta Zlatic - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/t-to-z/marta-zlatic/23 Feb 2024: with comprehensive structural and functional connectivity maps, and iv) use powerful genetic tools to selectively manipulate individual neurons to test models’ predictions and elucidate the functional roles of specific circuit motifs. -
Blue Sky Collaboration - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/blue-sky-collaboration/10 Jan 2024: The collaboration continues. A further goal is to test the TRIM21-binding small molecules as inhibitors of TRIM21 mediated neutralisation of viruses with a view to enhancing the efficacy of
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