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29 Nov 2023: Our impact. We are dedicated to advancing the field of cryo-EM structure determination. To help others in their structure determination efforts we make all our algorithm developments available through our open-source software package RELION. We are

14 Sep 2023: Proteins are the work horses of the living cell. Either alone or in complex with other proteins and/or other biological macromolecules, proteins perform the majority of the functions that are needed to keep the cell alive. Understanding how proteins

30 Nov 2023: Our people. Dongqi Zhang. Post-doc. Dongqi studied Pharmaceutical Sciences at Shandong University, and she did a PhD in Structural Pharmacology at Zhejiang University. Dongqi joined our group as a postdoc in November 2023 to work on laboratory-based

21 Jul 2023: They are awarded annually for achievements in the fields of physics, chemistry, physiology or medicine, literature, peace and economic sciences.

3 May 2024: Our publications. 2024. A. Burt, B. Toader, R. Warshmanage, A. von Kugelgen, E. Pyle, J. Zivanov, D. Kimanius, T.A.M. Bharat & S.H.W. Scheres (2024) "An image processing pipeline for electron cryo-tomography in RELION-5". bioRxiv 2024.04.26.591129.

21 Jul 2023: Where possible, scientists are encouraged to exploit and disseminate their discoveries – helping to improve quality of life and the economic competitiveness of the UK and pioneering new research methods.

29 Apr 2024: In order to test whether the mode of DNA binding revealed by cryo-EM also occurs in cells, we genetically engineered E.

21 Mar 2024: Yes - welcome. Crystallographic Object-Oriented Toolkit. Coot is for macromolecular model building, model completion and validation, particularly suitable for protein modelling using X-ray data. Coot displays maps and models and allows model

22 Nov 2023: How can we test for, treat and prevent SARS-CoV-2 infection? Collaborators across the LMB have developed new models, assays, and screening platforms with the goal of investigating new methods ... and drugs that could be used to test for or treat COVID-19.

12 Feb 2024: I particularly enjoyed learning about and examining Drosophila melanogaster, as well as learning about how they could be used to aid research and test out theories in the lab.