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PPL number: | Granted: 24 Feb 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/maternal_and_neonatal_immunity_to_virus_infections_redacted.pdf18 Jun 2021: To test how effective vaccines are, pups will be infected with the viruses when adults. ... We will test all new medicines for treating virus infection in cells in the laboratory first, and only progress to animal experiments if positive results are -
PPL number: | Granted: 18 Feb 20 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/protection_after_heart_attack_or_stroke_nts_redacted.pdf19 Aug 2021: This project will develop and test novel protective drugs for heart attack and stroke, as well as the resulting organ damage of chronic heart failure or chronic neurological disability, in order ... The main aim of the license is to test protective -
PPL number: | Granted: 05 May 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/safety_efficacy_and_immunogenicity_of_regenerative_cellular_therapies_redacted.pdf18 Jun 2021: In the long-term (5-7 years), we expect that the findings of this study will result in the design of at least 1 human clinical trial to test the safety ... The purpose here will be to induce a disease, such as liver failure or diabetes, to test the -
PPL number: | Granted: 10 Apr 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/genetic_and_developmental_basis_of_morphological_variation_in_cichlid_fish_nts_expires2024_redacted.pdf13 Sep 2021: To identify genes responsible for coloration differences we will test if it is possible to interbreed different species with different colour patterns using in vitro fertilisation methods. ... Gene modifications are confirmed by collecting tissue -
PPL number: | Granted: 12 Nov 20 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/discovery_of_novel_compounds_for_the_treatment_of_dementia._nts_redacted.pdf19 Aug 2021: Over the same period, behavioural tests will be carried out once a week to test their ability to remain on a rotating cylinder and to cross a narrow beam. ... the expected number of studies to validate and test potential drugs for each project. -
PPL number: | Granted: 24 May 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_influencing_mammalian_digit_tip_regeneration_redacted.pdf18 Jun 2021: 4. Test experiments, called pilot experiments, will be used to calculate the amount of a substance that we can safely inject into the animal. ... These test experiments will help us to work out how much this amount is but will only use a small number of -
PPL number: | Granted: 04 Apr 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/the_study_of_epithelial_cancer_genes_nts_expires2022_redacted.pdf13 Sep 2021: mice, and; 4) in some cases, we will surgically transplant modified breast cells into the cleared breast tissue (Fatpad) of mice to test the effect of the certain genetic mutations on -
PPL number: | Granted: 10 Jun 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_diseases_with_an_inflammatory_component_nts_expires2022_redacted.pdf13 Sep 2021: Because targets for these diseases are developing we are mostly focusing on helping the client with proof of concept studies, developing cell based assays to test their compounds in and then ... The techniques used for dosing with test agents and -
PPL number: | Granted: 04 Mar 21 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_and_treatment_of_pulmonary_vascular_diseases_redacted.pdf18 Jun 2021: We will use this knowledge to develop and test new treatment strategies for pulmonary arterial hypertension and other related conditions. ... the length of the total process until we test the level of disease is 7 weeks. -
PPL number: | Granted: 18 Nov 19 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/generation_of_novel_antibodies_with_therapeutic_potential_nts_redacted.pdf20 Aug 2021: Pilot studies involve using a small number of mice to test the safety and efficacy of a method before using it on a larger number of mice.
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