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Pharmacological evaluation of imaging agents and development of…
https://www.ubs.admin.cam.ac.uk/system/files/public/pharmacological_evaluation_of_imaging_agents_and_development_of_imaging_applications_and_methods_no_redacted.pdf30 Apr 2024: We currently use several tests, depending on the kind of imaging agent, before proceeding to animal studies as follows. -
AWERB Standing Minutes 28th February 2024_Redacted
https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_280224_redacted.pdf30 Apr 2024: The inclusion of further detail to support why specific tests are most appropriate for the science. ... Further detail required in the Animal Experience section. • The inclusion of a timeline to show when the tests will be performed and at what stage -
The development of novel therapies (including cell and gene based…
https://www.ubs.admin.cam.ac.uk/system/files/public/the_development_of_novel_therapies_including_cell_and_gene_based_approaches_for_parkinsons_and_hu_redacted.pdf30 Apr 2024: as in vitro (performed in a test tube, culture dish or elsewhere outside of a living organism) slice cultures. -
Genes and environment at the interface of inflammation, immunity and…
https://www.ubs.admin.cam.ac.uk/system/files/public/genes_and_environment_at_the_interface_of_inflammation_immunity_and_metabolism_non-technical_summa_redacted.pdf30 Apr 2024: Potential refinements include increased monitoring if test animals show earlier clinical signs or weight loss. -
AOC Minutes 19th January 2024
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_190124_redacted.pdf25 Apr 2024: had their PAT test this week. will have theirs next week. -
The genetic and developmental basis of morphological and behavioural…
https://www.ubs.admin.cam.ac.uk/system/files/public/the_genetic_and_developmental_basis_of_morphological_and_behavioural_variation_in_cichlid_fishes_no_redacted.pdf30 Apr 2024: Gene modifications are confirmed by collecting tissue biopsies (e.g. by removing a very small piece of fin or collecting skin swabs), which are then used for genetic tests. -
Cancer and its microenvironment! From mechanisms to translation…
https://www.ubs.admin.cam.ac.uk/system/files/public/cancer_and_its_microenvironment_from_mechanisms_to_translation_non-technical_summary_redacted.pdf30 Apr 2024: A key component of this project is to improve the diagnosis and treatment of human cancers; therefore, it is crucial to test and validate novel tools in preclinical models that involve -
AWERB 3Rs Minutes 2nd August 2023 Redacted
https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_020823_redacted.pdf14 May 2024: Researchers in the University’s Department of Surgery are using large animal models to understand why donated organs become damaged and unsuitable for transplantation, and to test promising new treatments. -
Remodelling of stem cells and niche cells from development and…
https://www.ubs.admin.cam.ac.uk/system/files/public/remodelling_of_stem_cells_and_niche_cells_from_development_and_regeneration_to_disease_non-technic_redacted.pdf30 Apr 2024: 4. Test experiments, called pilot experiments (which use a smaller number of animals; typically 3) will be used to calculate the amount of a substance that we can safely inject into -
3Rs Minutes 7th August 2019 Redacted
https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_07.08.19_redacted.pdf14 May 2024: Increased monitoring and establishing disease progression through blood tests, if NSGs are needed to be kept for an extended period of time. •
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