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21 Jul 2023: 2. transport by haemoglobin and the Bohr effect. He prepared specifically modified haemoglobins to test whether particular amino acids, some predicted from the X-ray crystallographic structure Perutz had just solved,

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21 Jul 2023: LMB discoveries help fuel the UK’s life sciences industry – the third largest contributor to economic growth.

23 Feb 2024: with comprehensive structural and functional connectivity maps, and iv) use powerful genetic tools to selectively manipulate individual neurons to test models’ predictions and elucidate the functional roles of specific circuit motifs.

the immune system, with applications for development of vaccines and diagnostic tests.

2. transport by haemoglobin and the Bohr effect. He prepared specifically modified haemoglobins to test whether particular amino acids, some predicted from the X-ray crystallographic structure Perutz had just solved, ... He prepared specifically modified

21 Jul 2023: Alongside applications in research, this capacity is also used for medical tests, such as to test for the presence of viral RNA, including in COVID-19 tests.

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20 Apr 2018: These remarkable cells can continue to keep their own 24 hour time in a test-tube for weeks even months on end.

26 Sep 2011: Overexpression of endocytic proteins in COS cells to test the effects of mutations in vivo. ... Liposome/lipid nanotube sedimentation assays to test lipid binding and specificity. (also immunoprecipitations, cloning, kinase assays, etc.).

20 Mar 2023: We then collaborated with Peter Cullen (Bristol University) to test the in vivo significance for protein trafficking in cells.

26 Sep 2011: Researching the reason immune responses are sprroessed during Yersinia infections.

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31 May 2024: The collaboration continues. A further goal is to test the TRIM21-binding small molecules as inhibitors of TRIM21 mediated neutralisation of viruses with a view to enhancing the efficacy of

Producing maps of how these neurons connect with each other allows scientists to build and test theories to explain how complex behaviours can arise from electrochemical signalling across neural circuits.

27 Sep 2019: A full map of the cells that make up the kidney will also be useful for researchers who want to grow kidney organoids in order to test drugs or study kidney

19 Jul 2024: https://www2.mrc-lmb.cam.ac.uk/news-events/lmb-news/ One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key

While here he continued to develop the use of Xenopus oocytes as a living test tube, demonstrating synthesis of haemoglobin from injected mRNA, and of 5S rRNA from injected DNA, as

During his PhD work, Christian studied what causes aggregation of mutant SOD1 in the test tube and in cells.

connectivity maps, and iv) use powerful genetic tools to selectively manipulate individual neurons to test modelsu2019 predictions and elucidate the functional roles of specific circuit motifs.