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The Body's Daily Clock
https://www2.mrc-lmb.cam.ac.uk/groups/mha/brain2.html20 Apr 2018: These remarkable cells can continue to keep their own 24 hour time in a test-tube for weeks even months on end. -
McMahon Group publications
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/papers.html20 Mar 2023: We then collaborated with Peter Cullen (Bristol University) to test the in vivo significance for protein trafficking in cells. -
McMahon Group techniques
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/techniqs/techniqs.html26 Sep 2011: Overexpression of endocytic proteins in COS cells to test the effects of mutations in vivo. ... Liposome/lipid nanotube sedimentation assays to test lipid binding and specificity. (also immunoprecipitations, cloning, kinase assays, etc.). -
Blue Sky Collaboration - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/blue-sky-collaboration/31 May 2024: The collaboration continues. A further goal is to test the TRIM21-binding small molecules as inhibitors of TRIM21 mediated neutralisation of viruses with a view to enhancing the efficacy of -
YopJ activation by IP6
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/Black_Plague/YopJ_IP6.html26 Sep 2011: Researching the reason immune responses are sprroessed during Yersinia infections. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/19288
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/19288 -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/18679
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/18679Producing maps of how these neurons connect with each other allows scientists to build and test theories to explain how complex behaviours can arise from electrochemical signalling across neural circuits. -
Mapping the human kidney - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/mapping-the-human-kidney/27 Sep 2019: A full map of the cells that make up the kidney will also be useful for researchers who want to grow kidney organoids in order to test drugs or study kidney -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/4132
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/4132While here he continued to develop the use of Xenopus oocytes as a living test tube, demonstrating synthesis of haemoglobin from injected mRNA, and of 5S rRNA from injected DNA, as -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/4399
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/4399During his PhD work, Christian studied what causes aggregation of mutant SOD1 in the test tube and in cells.
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