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Putting science skills to new use during the pandemic - MRC…
https://www2.mrc-lmb.cam.ac.uk/putting-science-skills-to-new-use-during-the-pandemic/17 Jul 2020: The people I have been working with at the test centre were truly amazing. ... It is only with your generous support that we have been able to test COVID-19 samples at such enormous scale. -
Atomic advance for cryo-EM - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/atomic-advance-for-cryo-em/21 Oct 2020: This collaboration started in early 2019 when Radu and Abhay Kotecha, a researcher at Thermo Fisher Scientific, wanted to test new cryo-EM hardware on a small membrane protein sample. -
Studying the spike protein of SARS-CoV-2 - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/studying-the-spike-protein-of-sars-cov-2/18 Aug 2020: development of better diagnostic tests. -
Discovery of a chaperone for membrane proteins - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/discovery-of-a-chaperone-for-membrane-proteins/19 Aug 2020: To investigate later steps in the insertion and assembly process, Patrick has now produced a series of incompletely assembled membrane protein intermediates in a test tube using ER membranes isolated from ... Returning to the test tube system, Patrick -
How alcohol-derived DNA damage is fixed - MRC Laboratory of Molecular …
https://www2.mrc-lmb.cam.ac.uk/how-alcohol-derived-dna-damage-is-fixed/4 Mar 2020: Although these crosslinks could form in just a few seconds in a cell, it took the better part of 3 years to make them in a test tube. -
A map to show the way to sense smell, temperature, and humidity - MRC …
https://www2.mrc-lmb.cam.ac.uk/a-map-to-show-the-way-to-sense-smell-temperature-and-humidity/23 Jul 2020: Producing maps of how these neurons connect with each other allows scientists to build and test theories to explain how complex behaviours can arise from electrochemical signalling across neural circuits. -
A new directed evolution technique to unlock the potential of XNAs -…
https://www2.mrc-lmb.cam.ac.uk/a-new-directed-evolution-technique-to-unlock-the-potential-of-xnas/20 Jul 2020: Alongside applications in research, this capacity is also used for medical tests, such as to test for the presence of viral RNA, including in COVID-19 tests. -
Max Perutz Lecture to be given by John Diffley - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/max-perutz-lecture-to-be-given-by-john-diffley/20 Feb 2020: Recently they have developed a way of using these machines to copy DNA in a test tube, giving an unprecedented view of this fascinating and essential process. -
A synthetic molecule that can restore lost connections in the brain - …
https://www2.mrc-lmb.cam.ac.uk/a-synthetic-molecule-that-can-restore-lost-connections-in-the-brain/28 Aug 2020: As well as observing reconnection of synapses, the team were able to measure improvements in behavioural tests, with restored motor coordination in cerebellar ataxia, better performance in memory tests in mouse -
Coot Cryo-EM Tutorial 2: Fitting and Mutating | Coot Development Blog
https://www2.mrc-lmb.cam.ac.uk/coot/blog/2020/10/20/Coot-Cryo-EM-main.html20 Oct 2020: Test, play, refine, yank until satisfied. Reset Geman-McClure alpha to 1:.
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