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Mechanism of ribosome stalling during translation of a poly(A) tail
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/NSMB_2019.pdf25 Nov 2019: RNCs were produced using this strategy in which one of three test sequences (7"K, 3"K and 1"K, as indicated) is positioned inside the ribosome tunnel. ... If a test sequence inserted downstream of the FLAG-SR region causes terminal stalling, production -
The ER membrane protein complex promotes biogenesis of sterol-related …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/JCS_2019.pdf18 Jan 2019: are shown (n=4). P0.01, P0.001 (Student’s t-test). 3. RESEARCH ARTICLE Journal of Cell Science (2019) 132, jcs223453. ... are shown (n=3).P0.001, P0.0001 (Student’s t-test). Reconstitution of Δ5 (D) and Δ6 cells (E) with empty vector control (EV), -
The structure of bactofilin filaments reveals their mode of membrane…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Deng2019Natmicro.pdf26 Aug 2019: Nature Microbiology, doi:10.1038/s41564-019-0544-0 -
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https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/elife_2019.pdf29 May 2019: To test whether the role of TMED10 in GFP-PrP degradation depends on complex formation, we. -
Biallelic Variants in ASNA1, Encoding a Cytosolic Targeting Factor of …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/CircGen_2019.pdf1 Dec 2019: Circ Genom Precis Med. 2019;12:e002507. DOI: 10.1161/CIRCGEN.119.002507 September 2019 397. BACKGROUND: Pediatric cardiomyopathies are a clinically and genetically heterogeneous group of heart muscle disorders associated with high morbidity and -
Cryo‐EM structure of the MinCD copolymeric filament from Pseudomonas…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Szewczak-Harris_et_al-2019-FEBS_Letters.pdf22 Jul 2019: by MinD’s MTS. To test whether P. aeruginosa MinC and MinD pro-. -
Structural Analysis of the Interaction between the BacterialCell…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/mBio-2018-Kureisaite-Ciziene-e01346-18.full.pdf5 May 2019: To test this further, we investigated the bindingof the periplasmic domain of FtsN to immobilized FtsQ as a control (Fig. ... S5]). Because of the very low level of FtsB incells and the low protein levels needed to complement in our assays, we have -
TTC5 mediates autoregulation of tubulin via mRNA degradation
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2019.pdf19 Nov 2019: Not significant (n.s.) and p < 0.001 () in paired Student’s t tests are indicated. -
Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/WWWrobots/PDF/Publications/acs.biochem.9b00296.pdf31 Jul 2019: acid, 0.75% gallic acidmonohydrate, and 0.75% N-vanillylnonanamide] (plate LMB22, an in-house test formulation of the MORPHEUS IIIcrystallization screen); crystals of Collect 2/PDB entry 6G6J,20% PEG
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