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Greg Winter: Pioneering antibody drugs - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/greg-winter-pioneering-antibody-drugs/8 Mar 2013: by the MRC with the MRC Millennium Medal which recognises research that has led to significant health and economic benefits. -
Monoclonal antibodies; from their debut to blockbuster status - MRC…
https://www2.mrc-lmb.cam.ac.uk/monoclonal-antibodies-from-their-debut-to-blockbuster-status/15 Aug 2013: They’re found in home-testing kits for pregnancy, hospital tests for MRSA, and in six out of ten of the best-selling drugs today. -
Day of celebration as Her Majesty The Queen opens the new LMB…
https://www2.mrc-lmb.cam.ac.uk/day-of-celebration-as-her-majesty-the-queen-opens-the-new-lmb-building/23 May 2013: UK’s economic competitiveness. -
Discovery of the genetic basis of a rare immune disease - MRC…
https://www2.mrc-lmb.cam.ac.uk/discovery-of-the-genetic-basis-of-a-rare-immune-disease/22 Oct 2013: A simple genetic test can tell if the patient has the mutation or not. -
Novel technology useful for development of gene and drug therapies…
https://www2.mrc-lmb.cam.ac.uk/novel-technology-useful-for-development-of-gene-and-drug-therapies-licensed-to-local-company/10 Sep 2013: In order to develop such therapeutics, it is necessary to test a wide variety of peptide-cargo combinations to determine the optimal peptide for delivery of the drug cargo for the ... This new technology enhances the speed of the early stage drug -
Structure and superorganization of acetylcholinereceptor–rapsyn…
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/pnas13.pdf3 Jul 2013: 1,582 μm2;fitted skew normal distribution maximum: 5,522 μm2; n = 2,340;P < 0.001 by Mann–Whitney test), confirming the importance ofrapsyn for maintaining a high receptor ... The statistical significance of the dif-ference between those datasets was -
pnas201313978 4601..4610
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/pnas2013duman.pdf23 Dec 2013: characteristic of membrane-binding amphipathichelices (30, 31).To test whether this amphipathic helix is able to recruit pro-. ... To test functionalities of the SepF mutants, the sepF mutationswere then introduced into a B. -
Twinning and other pathologies Andrey Lebedev CCP4 OD-‐structures…
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/pathologies_and_twinning.pdf11 Jun 2013: Twinning tests summary. Space group validaAon. 04/06/2013 58 Crystallography Course LMB. ... Twinning tests summary. Space group validaAon. 04/06/2013 61 Crystallography Course LMB. -
Twinning and other pathologies Andrey Lebedev CCP4 OD-‐structures…
https://www2.mrc-lmb.cam.ac.uk/download/twinningaandaotherapathologiesa-andreyalebedeva-a/?wpdmdl=18788&refresh=6693eb1a48551172097001011 Jun 2013: Twinning tests summary. Space group validaAon. 04/06/2013 58 Crystallography Course LMB. ... Twinning tests summary. Space group validaAon. 04/06/2013 61 Crystallography Course LMB. -
Expression, purifica0on, characteriza0on, and crystalliza0on So how…
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/20130430_Cryst_course.pdf2 May 2013: Beware of the layer of cold air over the liquid nitrogen (2) Test crystal at room temp: Mitegen crystal sleeve: MicroRT Test different cryos & precipitant concentra-ons Remove any mother liqour
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