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From bench to blockbuster: the story of HUMIRA® – best-selling drug…
https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-exhibitions/from-bench-to-blockbuster-the-story-of-humira-best-selling-drug-in-the-world/21 Jul 2023: test adalimumab as a treatment for rheumatoid arthritis. ... Examples include: cancer diagnosis; HIV diagnosis, blood group tests, transplant compatibility, pregnancy tests and more recently, COVID lateral flow tests. -
Anne Bertolotti: Finding clues to combat neurodegenerative disease -…
https://www2.mrc-lmb.cam.ac.uk/life-at-the-lmb/profiles/anne-bertolotti-finding-clues-to-combat-neurodegenerative-disease/21 Jul 2023: she says inadvertently became a test for how the LMB would perceive someone who wanted to be both a mother and a scientist. -
Influence of lipid bilayer on the structure of the muscle-type…
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/pnasS24.pdf30 Apr 2024: 121 No. 19 e2319913121 https://doi.org/10.1073/pnas.2319913121 5 of 6. to test whether nanodisc reconstitution provides a means to recapit-ulate accurately the conformations of the receptor -
Liz Miller: Signed, sealed, delivered – protein trafficking in the…
https://www2.mrc-lmb.cam.ac.uk/life-at-the-lmb/profiles/liz-miller-signed-sealed-delivered-protein-trafficking-in-the-endoplasmic-reticulum/21 Jul 2023: Despite Liz having the security of tenure, she and Marcus started looking for other places to live and work, as the economic climate meant that it was unlikely that Marcus would -
The patterned assembly and stepwise Vps4-mediated disassembly of…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Hurtig%202023%20sciadv.ade5224.pdf16 Jul 2023: S1E). As a further test of thisfinding, we expressed the Vps4E209Q plasmid in a cell line carryinga thymidine kinase homolog (hereafter called STK). ... 3A).To test the functional significance of this patterned assembly ofESCRT-III polymers, we used -
CURRICULUM VITAE
https://www2.mrc-lmb.cam.ac.uk/groups/bienz/wp-content/uploads/sites/23/BienzCV_March2024.pdf11 Apr 2024: signalling pathway in the Drosophila midgut. Development 122, 849-858. 47. Hart K & Bienz M (1996) A test for cell autonomy, based on di-cistronic messenger. -
Substrate-driven assembly of a translocon for multipass membrane…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Nature_2022b.pdf19 Aug 2023: To test whether internal loop translocation occurs at the secretory translo-con, we analysed biogenesis intermediates of EAAT1, an eight-TMD protein28 with a glycosylated luminal loop after TMD3 (Fig. ... Statistical analyses in e,g were performed by
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