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41 - 50 of 61 search results for Economics test |u:www.ubs.admin.cam.ac.uk where 12 match all words and 49 match some words.
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  2. Mechanisms of organ development and disease (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_of_organ_development_and_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: This will allow us to change the signalling within particular cells and test the consequences on the mechanics and development of the whole organ. ... Why were they not suitable? It is not possible to entirely replace animal experiments for this project
  3. The development of in vivo expressed biologics as a platform for…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_development_of_in_vivo_expressed_biologics_as_a_platform_for_novel_therapeutic_agents_non-techn_redacted.pdf
    30 Apr 2024: This work will make extensive use of pilot studies, as most of the test substances will be by definition novel, as they concern novel technologies or modalities (method of treatment). ... Pilot or tolerability studies will be carried out for new models
  4. Breeding and maintenance of rodents for drug discovery platform

    https://www.ubs.admin.cam.ac.uk/system/files/public/breeding_and_maintenance_of_rodents_for_drug_discovery_platform_non-technical_summary_redacted.pdf
    29 Apr 2024: A small subset of mice will undergo a blood test to check how much of a certain marker of interest they have (for example, a protein). ... The best, non-invasive way to monitor disease progression is to test the urine for protein.
  5. Embryonic origins of heart disease

    https://www.ubs.admin.cam.ac.uk/system/files/public/embryonic_origins_of_heart_disease_non-technical_summary_redacted.pdf
    29 Apr 2024: This will contribute to a reduction in the burden of developmental origins of heart disease, thereby having a positive clinical, economic and societal impact on health. ... The real ethical, biological and economic value of the avian relative to other
  6. New treatments for renal and liver disease (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/new_treatments_for_renal_and_liver_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: Renal function can be assessed by tests performed in urine or blood collected from the animals. ... For example we use human kidney organoids to test drug activity in certain projects.
  7. Vaccine development and fundamental reseach on viruses of medical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/vaccine_development_and_fundamental_research_on_viruses_of_medical_importance_non-technical_summary_redacted.pdf
    29 Apr 2024: We primarily use adult female mice, hamsters and guinea pigs to test our vaccines. ... There exists no cell-based model or less sentient model to test vaccines.
  8. Implantation of seeded scaffolds for tissue!organ development…

    https://www.ubs.admin.cam.ac.uk/system/files/public/implantation_of_seeded_scaffolds_for_tissueorgan_development_non-technical_summary_redacted.pdf
    30 Apr 2024: endoscopy, bronchoscopy, MRI/CT/PET) and non imaging techniques (e.g. blood tests and functional assays).
  9. Generation and screening of companion animal therapeutics.…

    https://www.ubs.admin.cam.ac.uk/system/files/public/generation_and_screening_of_companion_animal_therapeutics._non-technical_summary_redacted.pdf
    30 Apr 2024: rodent models to test how well they remain detectable and/or functional over a defined period of time. ... The information gathered here will inform us which drug is best suited to take forward to test in the target animal species.
  10. Mouse developmental genetics to study neurodevelopment and disease…

    https://www.ubs.admin.cam.ac.uk/system/files/public/mouse_developmental_genetics_to_study_neurodevelopment_and_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: licence. Furthermore, when possible, we will generate primary cell lines from mouse brains which will allow us to test some of our hypotheses in vitro prior to performing elaborate experiments that ... 1) We will perform pilot studies and in vitro tests
  11. Interventions in pregnancy effects of obesity on maternal and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/interventions_in_pregnancy_effects_of_obesity_on_maternal_and_offspring_health_non-technical_summa_redacted.pdf
    30 Apr 2024: After this she may undergo a glucose tolerance test (as described in point 5) prior to her being humanely killed and her tissues collected and stored for laboratory analyses. ... c) Glucose or insulin tolerance tests which require injection of either

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