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Microscopy, 2021, 1–6doi:https://doi.org/10.1093/jmicro/dfab023…
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/mic21.pdf26 Jul 2021: For exam-ple, X-ray diffraction of myelin, the best studied cell membrane,yields peak-to-peak values of 43–48 Å [15,16]. -
KWRM_A_992668_O
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-3.pdf20 Oct 2015: For exam-ple, it might induce plasticity of targetneurons’ intrinsic excitability, alteringionic conductances,17,18 or it might affectsynaptic connections other than the tar-geted ones through non-Hebbian (noncoincidence-dependent) -
Tutorial 5: Hypothesis TestingRob Nicholls –…
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/tutorials/hypothesis_testing.pdf26 Mar 2014: A two-tailed test might be used to test the hypothesis that both classesperformed equally well in the exam. ... However, a one-tailed test might be used totest the hypothesis that class 1 performed better than class 2 in the exam. -
Tutorial 5: Hypothesis TestingRob Nicholls –…
https://www2.mrc-lmb.cam.ac.uk/download/tutorial-5-hypothesis-testing/?wpdmdl=18817&refresh=66840f0900600171993063326 Mar 2014: A two-tailed test might be used to test the hypothesis that both classesperformed equally well in the exam. ... However, a one-tailed test might be used totest the hypothesis that class 1 performed better than class 2 in the exam. -
Organization of spines on the dendritesof Purkinje cellsJohn O’Brien…
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/pnas06.pdf25 Jul 2006: The images again revealed exam-ples of lines of regularly spaced spines inclined at small angles tothe axis of the shaft (Fig. -
Tutorial: Introduction to RRob Nicholls – nicholls@mrc-lmb.cam.ac.uk…
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/tutorials/introduction_to_r.pdf6 Mar 2014: For exam-ple, basic mathematical functions available include: log, exp, sqrt, abs, sin, cosand tan. ... For exam-ple, the command:. x <- "some text". results in x being of mode ‘character’. -
Transmembrane Domain Modulates Sorting of MembraneProteins in…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/29_Karsten_V_JBC_2004.pdf2 Jun 2004: Coverslips werewashed in phosphate-buffered saline and mounted in Moviol for exam-ination by epifluorescence microscopy. -
d402_16g 822..826
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/15_Hegde_RS_Nature_1999.pdf9 Dec 1999: Furthermore, biochemical and pathological exam-ination of representative brain tissue from animals depicted inFig. -
"Cytotoxicity of Aberrant Proteins". In: Encyclopedia of…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/50_Ashok_A_ELS_2008.pdf25 Sep 2008: Each of these basic cellbiological principles will be highlighted by specific exam-ples taken from diseases that are the direct consequence ofaberrant proteins generated from mutated genes. -
mmi_4133.fm
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Spo0J%202004.pdf30 Jun 2004: 5C). The C-terminal fragment (Spo0J 223–269) was exam-ined by sedimentation velocity and gave a well-shaped,symmetrical boundary (Fig. -
doi:10.1016/j.cub.2004.09.077
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Snx1PeteCullen2004/Snx1PeteCullen2004.pdf23 Nov 2004: evidence for a mammalian retromer [6, 7, 26], we exam-ined the relationship between SNX1 and the CI-MPR.We followed the trafficking of internalized CI-MPR enroute to its -
Monitoring chaperone engagement of substratesin the endoplasmic…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/39_Snapp_EL_PNAS_2006.pdf21 Sep 2006: For exam-ple, treatment with Puro or Pact inhibits new protein synthesis, resultinginitially in chaperone-bound maturing polypeptides (B) followed by a quies-cent ER (A) in which substrate polypeptides have -
bc219914979p
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10329700.pdf20 Apr 2002: For exam-ple, it has been shown that diacylglycerol enhances arachidonicacid release in vivo in a phorbol 12-myristate 13-acetate-acti-vated signaling pathway (44) and cPLA2 membrane penetra-tion -
Tutorial: Introduction to RRob Nicholls – nicholls@mrc-lmb.cam.ac.uk…
https://www2.mrc-lmb.cam.ac.uk/download/tutorial-introduction-to-r-rob-nicholls-nichollsmrc-lmb-cam-ac-uk-mrclmbstatistics-course-2014/?wpdmdl=18813&refresh=66840f07a2ecf17199306316 Mar 2014: For exam-ple, basic mathematical functions available include: log, exp, sqrt, abs, sin, cosand tan. ... For exam-ple, the command:. x <- "some text". results in x being of mode ‘character’. -
x15959u064
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Reim_Brose2001.pdf17 Mar 2003: stimulation. We averagedEPSCs from double mutant and control cells and exam-ined the time course of release (Figure 4C). -
TH EJ OU RN AL OF CE LL BIO ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/53_Hegde_RS_JCB_2008.pdf22 Jul 2008: are infl uenced by the cell type and culture conditions used ( Levine et al., 2005 ). And fi nally, exam-ples have been described in which alternative splice variants or alternative translation -
Recognition and Degradation of Mislocalized Proteins in Health and…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/CSHL_Persp_2019.pdf8 Mar 2019: One notable exam-ple is represented by the Asi ubiquitin ligasecomplex located in the inner nuclear membrane.The inner membrane is continuous with theouter nuclear and ER membranes via nuclearpore complexes -
, 130081, published 7 August 20133 2013 Open Biol. ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Open%20Biol.-2013-TakedaCombined.pdf25 Sep 2013: We further characterized these cytokinesis defects by exam-ining Syndmut1 primary spermatocytes by immunofluorescencemicroscopy. ... TheDrosophila genome encodes several uncharacterized C2domain-containing proteins, and it will be interesting to exam-ine -
Mediation, Modulation, and Consequences of Membrane-Cytoskeleton…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/DohertyMcMahonAnnRevBiophys08.pdf22 May 2008: A great deal of work has exam-ined this interface to attempt to understand,at a mechanistic level, how processes that re-quire maintenance of, or changes in, plasmamembrane morphology are ... For exam-ple, the importance of the myriad links me-diating -
doi:10.1016/j.cell.2006.01.047
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/16615893.pdf18 Apr 2006: at the same time or are mutually exclusive. We first exam-. -
doi:10.1016/j.str.2008.06.010
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/18786397.pdf3 Sep 2008: The ability. of Vps4 to disassemble these chimeric filaments was also exam-. -
#¥1D
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/11_Hegde_RS_Science_1998.pdf3 Feb 1998: To explore this idea further, we exam-ined brain tissue from a GSS patient todetermine whether in vivo, increased lev-els of transmembrane forms of PrP couldbe detected. -
Biallelic Variants in ASNA1, Encoding a Cytosolic Targeting Factor of …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/CircGen_2019.pdf1 Dec 2019: For exam-ple, at 8 dpf only 38% of fish that were injected with wild-type human ASNA1 mRNA had died or showed absent blood flow compared with 75% of noninjected -
The Jour nal o f Cel l Bio logy ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/24_Fons_RD_JCB_2003.pdf6 Feb 2003: In addition, the full-length proteins were analyzed in parallel. (B) Trans-location intermediates at 56 residues beyond the signal of either Prl or PrP–Prl were exam-ined for protease -
elifesciences.org Szwedziak et al. eLife 2014;3:e04601. DOI:…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/FtsZ_Piotr_eLife_2014.pdf31 Dec 2014: Filaments within the liposomes had very different curvatures, for exam-ple in Figure 3D, filaments seemed to go round the liposome at a very large diameter, compared to the ones in -
4380 | G. J. Doherty et al. Molecular Biology ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Doherty2011/DohertyGRAF_MBC2011.pdf17 Jan 2012: We therefore exam-ined whether induced PLAs and podosomes contained the GM1 receptor, a glycosphingolipid that is enriched in microdomains. -
Molecular Biology of the CellVol. 16, 279 –291, January ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/32_Levine_CG_MBC_2005.pdf21 Dec 2004: For exam-ple, the secretory protein apolipoprotein E (apoE) has beensuggested to interact with the neurofilament Tau in thecytosol to induce neurofibrillary tangles (Huang et al., 2001;Ljungberg et al., 2002; -
Volume 22 May 15, 2011 1625 Cytosolic aggregates perturb ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/69_Chakrabarti_O_MBC_2011.pdf11 Nov 2011: In cells containing mCFP-PrP40–231 aggregates, we observed increased in-tracellular accumulation of CRFR1 in 20% of cells (Table 1; exam-ples in Figure 7). -
Structural Analysis of the Interaction between the BacterialCell…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/mBio-2018-Kureisaite-Ciziene-e01346-18.full.pdf5 May 2019: Structural Analysis of the Interaction between the BacterialCell Division Proteins FtsQ and FtsB. Danguole Kureisaite-Ciziene,a Aravindan Varadajan,b Stephen H. McLaughlin,a Marjolein Glas,b Alejandro Montón Silva,c. Rosa Luirink,b Carolin -
Molecular mechanism and physiological functions of clathrin-mediated…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/McMahon%20NRMB%202011.pdf19 Jul 2011: 3b). Yeasts (for example, Saccharomyces cerevisiae) and plants (for exam-ple, Arabidopsis thaliana) have very small coated pits of 35– 60 nm in diameter (the exterior diameter comprising the -
Science Journals — AAAS
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Science_2021.pdf26 Aug 2021: Thus, the problemof subunit imbalance, although enhancedby genomic dysregulation in cancer cells, isnonetheless appreciable in noncancer cells.These proteomic observations were exam-. -
ANRV378-BI78-31.tex
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/DohertyMcMahonAnnRevBiochem09.pdf27 Apr 2009: ANRV378-BI78-31 ARI 14 March 2009 13:23. R. E VI E W. S. IN. AD V A. NC. E. Mechanisms of EndocytosisGary J. Doherty and Harvey T. McMahonMRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 0QH,United Kingdom; email: -
coot-user-manual.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot-user-manual.pdf28 Sep 2012: set-scroll-by-wheel-mouse 0). (the default is 1 [on]). 2.7 Selecting Atoms. Several Coot functions require the selecting of atoms to specify a residue range (for exam-ple:
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