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18 Aug 2015: The development of a direct replacement test can takemany years, so potential for ‘avoidance’ should always be explored. ... Bacterial tests for mutation are used to test almost all typesof chemical for mutagenicity.

30 Apr 2024: Hence, although individual elements of CVD can be modelled in a 'test tube' (e.g. ... Thus, when we use animal models this will be because we typically have several years worth of 'test tube' experiments that support the use of animal experiments for

30 Apr 2024: Motor behaviour and cognitive tests will place the mice shortly in an unfamiliar environment. ... To assess motor behaviour, we will perform tests such as Catwalk, Rotarod, and Grip strength and to assess cognitive behaviour, we will perform Barnes maze

8 Jan 2015: the administration of any substance or article to an animal for research purposes in accordance with an animal test certificate granted under the veterinary Medicines Regulations 2011. • ... www.nerc.ac.uk/publications/corporate/ethics.asp Natural

30 Apr 2024: The cost of mental health disorders to the UK in terms of social, economic and health factors is extremely high. ... As we are interested in adult behaviour, the majority of our behavioural tests will be conducted in adult animals.

18 Jun 2021: The project will inform the development, and test the feasibility of novel therapeutic strategies to treat heart failure. ... Thus, animal experiments are essential to understand regulatory mechanisms and to design and test potential new therapies.

30 Apr 2024: As we are interested in adult behaviour, the majority of our behavioural tests will be conducted in adult animals. ... We perform these manipulations to test the impact of early life stress on the behaviour of the offspring as adults.

19 Aug 2021: This project aims to improve our understanding of the cellular mechanisms that underlie IR injury and test the safety and efficacy of promising novel therapeutic agents. ... This project will generate academic outputs, new treatment products, and the

30 Apr 2024: neurophysiological basis of visual cognition and memory will have far reaching social and economic implications. ... This test is important to allow animals to be directed into studies that they are most appropriate for.

18 Sep 2015: Code of Practice for the Housing and Care of Animals Bred, Supplied or Used for Scientific Purposes. December 2014. 44389_00 Cover 10mm spine.indd 1 15/12/2014 17:34. Code of Practice for the Housing and Care of Animals Bred, Supplied or Used for