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LMB 365 - Day 66 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-66/6 Mar 2019: In order to minimise the transportation of live mice, and limit any potential stress caused to the animals, cryopreserved sperm is often shared between establishments, rather than live mice. ... This is an example of 3Rs (Replacement, Reduction and -
Mapping the human kidney - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/mapping-the-human-kidney/27 Sep 2019: A lack of tissue availability has limited research into human kidney function and animal research hasn’t translated into treatments for human patients. ... UK, EMBO, Human Frontier Science Program, Children with Cancer UK, and Cambridge Biomedical -
LMB 365 - Day 252 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-252/9 Sep 2019: Published on. 9 September, 2019. Day 252 of #LMB365 shows the LMB’s Research Office who had an awesome team day recently and visited the LMB’s animal facility. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
LMB 365 - Day 266 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-266/23 Sep 2019: The Biological Services Group provides some form of environmental enrichment to all mice as part of their commitment to improving animal welfare. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
LMB 365 - Day 64 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-64/4 Mar 2019: Fluorescent tools like these help researchers to dissect which neurons make up circuits in the brain that control the animal’s behaviour. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
LMB 365 - Day 123 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-123/2 May 2019: Ty3 and the human virus HIV-1 diverged from a common ancestor that existed before the divergence of plants and animals 1.5 billion years ago. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
Michael Rossmann 1930 – 2019 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/michael-rossmann-1930-2019/15 May 2019: At a talk by Dorothy Hodgkin, at the International Crystallography Meeting in Montreal, he heard about the work on the structure of proteins being undertaken in Cambridge, England. ... Michael’s discoveries have suggested a shared origin for plant and -
Decoding how detection of odours leads to diverse behaviours in flies …
https://www2.mrc-lmb.cam.ac.uk/decoding-how-detection-of-odours-leads-to-diverse-behaviours-in-flies/17 Jun 2019: into the innate odour processing pathway of a behaviourally complex animal, the vinegar fly. ... Importantly, the researchers found that the same neuron type drove the same response in different animals. -
Madeline Lancaster explains brain organoids to The Times - MRC…
https://www2.mrc-lmb.cam.ac.uk/madeline-lancaster-explains-brain-organoids-to-the-times/8 Oct 2019: us apart from animals (story behind paywall). ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
Student prizes awarded for outstanding doctoral research - MRC…
https://www2.mrc-lmb.cam.ac.uk/student-prizes-awarded-for-outstanding-doctoral-research/28 Oct 2019: said. Going forward, he wants to continue investigating the fly brain. “There is a lot we don’t know about this small animal, and we can use it to ask questions ... that we have no hope of answering in larger animals,” added Alex. -
Rebecca Taylor: A worm's eye view of stress and ageing - MRC…
https://www2.mrc-lmb.cam.ac.uk/rebecca-taylor-a-worms-eye-view-of-stress-and-ageing/23 Sep 2019: What’s interesting is that the effect of this constitutive stress signal is to change the way an animal ages,” says Rebecca. ... In good conditions, it tells the animal to put all its efforts into reproduction. -
How eating feeds into the body clock - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/how-eating-feeds-into-the-body-clock/25 Apr 2019: The researchers went on to show that if insulin is provided at the wrong biological time, when animals would normally be resting, it disrupts normal circadian rhythms: reducing their amplitude. ... Francis Crick Avenue, Cambridge Biomedical Campus, -
Activation of lysosomes allows worms to live longer and may protect…
https://www2.mrc-lmb.cam.ac.uk/activation-of-lysosomes-allows-worms-to-live-longer-and-may-protect-against-neurodegenerative-diseases/17 Jul 2019: However, it was not clear how the longer lifespan of these animals was orchestrated. ... 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
The LMB welcomes Marta Zlatic as a new Group Leader - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/the-lmb-welcomes-marta-zlatic-as-a-new-group-leader/2 Dec 2019: A main aim of Marta’s group’s work is to understand how neuronal circuitry enables animals to learn and to select an appropriate response based on the learnt information. ... Marta completed her PhD and postdoctoral work at the University of Cambridge -
Identification of a potential therapeutic target in colorectal cancer …
https://www2.mrc-lmb.cam.ac.uk/identification-of-a-potential-therapeutic-target-in-colorectal-cancer-initiation/13 Feb 2019: Importantly, Wnt signalling is also active in the stem cells found in most tissues in adult animals. ... 2024 MRC Laboratory of Molecular Biology,. Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. -
The LMB welcomes Albert Cardona as a new Group Leader - MRC…
https://www2.mrc-lmb.cam.ac.uk/the-lmb-welcomes-albert-cardona-as-a-new-group-leader/2 Dec 2019: Albert’s group then plan to use this information to develop and experimentally test theoretical models that can explain the variety of animal behaviours elicited by different stimuli. ... Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 -
Redefining the importance of astrocytes in the brain’s master body…
https://www2.mrc-lmb.cam.ac.uk/redefining-the-importance-of-astrocytes-in-the-brains-master-body-clock/11 Jan 2019: in neurons of the SCN revealed that the animals were on slightly different cycles: astrocyte-driven rhythms were found to be approximately one hour shorter, reflecting the specific cell-autonomous features ... Francis Crick Avenue, Cambridge Biomedical -
Mariann Bienz: Fascinating flies - Drosophila and the molecular…
https://www2.mrc-lmb.cam.ac.uk/mariann-bienz-fascinating-flies-drosophila-and-the-molecular-biology-of-development-and-disease/8 Oct 2019: of genes could give rise to positional information able to dictate the body plan of an animal. ... I was completely uprooted – my English was rotten, I knew no-one in Cambridge. -
Structure of a post-catalytic human spliceosome improves…
https://www2.mrc-lmb.cam.ac.uk/structure-of-a-post-catalytic-human-spliceosome-improves-understanding-of-splicing-control/1 Feb 2019: This is the first multicellular animal-specific protein to be found in the active site of the spliceosome. ... This work was funded by the MRC, ERC, EMBO, Marie Sklodowska-Curie Actions, and a Cambridge-Rutherford Memorial PhD Scholarship. -
Biallelic Variants in ASNA1, Encoding a Cytosolic Targeting Factor of …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/CircGen_2019.pdf1 Dec 2019: Medical Research Council Laboratory of Molecular Biology, Cambridge Biomedical Campus, United Kingdom (M.H.K., R.S.H.). ... Animal models for ASNA1-mediated TA protein insertion related genes …………….….34. SUPPLEMENTAL FIGURES.
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