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Publications From the Munro Lab
https://www2.mrc-lmb.cam.ac.uk/groups/munro/publications-2/Cattin-Ortolá J, Kaufman, JGG , Gillingham, AK, Wagstaff JL, Sew-Yeu Peak-Chew SY, Stevens TJ, Boulanger J, Owen DJ, Munro S. ... Rocha JJ, Jayaram SA, Stevens TJ, Muschalik N, Shah RD, Emran S, Robles C, Freeman M, Munro S. -
Mariann Bienz - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/emeritus/mariann-bienz/16 Feb 2024: eLife, e09073. Gammons M, Renko M, Johnson CM, Rutherford TJ & Bienz M (2016). ... Mol Cell 64: 92-104. van Tienen LM, Mieszczanek J, Fiedler M, Rutherford TJ & Bienz M (2017). -
Emmanuel Derivery - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/a-to-g/emmanuel-derivery/23 Feb 2024: Wu K, Bai H, Chang Y, Redler R, McNally K, Sheffler W, Brunette TJ, Hicks DR, Morgan TE, Stevens TJ, Broerman A, Goreshnik I, DeWitt M, Chow CM, Shen Y, Stewart -
https://www2.mrc-lmb.cam.ac.uk/groups/munro/wp-json/wp/v2/pages/260
https://www2.mrc-lmb.cam.ac.uk/groups/munro/wp-json/wp/v2/pages/260Rocha JJ, Jayaram SA, Stevens TJ, Muschalik N, Shah RD, Emran S, Robles C, Freeman M, Munro S. ... adaptors for sorting into intra-Golgi transport vesicles./strong/a Welch LG, Peak-Chew SY, Begum F, Stevens TJ, Munro S. -
publications | The Bacterial Cytoskeleton and other Molecular Machines
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/page-4/index.html29 Apr 2024: Jan Löwe's group at the MRC Laboratory of Molecular Biology. Jan Löwe's ORCID identifier: 0000-0002-5218-6615. For statistics such as h-index and citation numbers please consult Google Scholar: Jan Löwe's profile. 2024. Hale V., Hooker J., Russo C -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/36042
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/36042{"id":36042,"date":"2023-08-09T09:56:06","date_gmt":"2023-08-09T08:56:06","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=36042"},"modified":"2023-08-09T09:56:07","modified_gmt":"2023-08-09T08:56:07","slug":"a-database-to-identify-important-gen -
Mapping the human kidney - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/mapping-the-human-kidney/27 Sep 2019: Stewart, BJ., Ferdinand, JR., Young, MD., Mitchell, TJ., Loudon, KW., Riding, AM., Richoz, N., Frazer, GL., Staniforth, JUL., Vieira Braga, FA., Botting, RA., Popescu, D-M., Vento-Tormo, R., Stephenson, E., -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/15911
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/15911 -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/15366
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/15366{"id":15366,"date":"2019-09-27T10:15:30","date_gmt":"2019-09-27T09:15:30","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=15366"},"modified":"2019-11-21T10:16:12","modified_gmt":"2019-11-21T10:16:12","slug":"mapping-the-human-kidney","status":" -
New understanding of protein abundance control - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/new-understanding-of-protein-abundance-control/15 Nov 2019: Lin, Z., Gasic, I., Chandrasekaran, V., Peters, N., Shao, S., Mitchison, TJ., Hegde, RS. -
CURRICULUM VITAE
https://www2.mrc-lmb.cam.ac.uk/groups/bienz/wp-content/uploads/sites/23/BienzCV_March2024.pdf11 Apr 2024: co-corresponding authors. 116. van Tienen LM, Mieszczanek J, Fiedler M, Rutherford TJ & Bienz M (2017) Constitutive. ... 1 equal contribution. 129. Mieszczanek J, Strutt H, Rutherford TJ, Strutt D, Bienz M & Gammons MV (2022). -
Molecular basis for membrane remodelling and organization
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/F-BAR_proteins/JMConference/speakerprofiles.html21 Nov 2010: Giraudo CG, Garcia-Diaz A, Eng WS, Chen Y, Hendrickson WA, Melia TJ, Rothman JE. ... Giraudo CG, Garcia-Diaz A, Eng WS, Yamamoto A, Melia TJ, Rothman JE. -
A database to identify important genes of unknown function for…
https://www2.mrc-lmb.cam.ac.uk/a-database-to-identify-important-genes-of-unknown-function-for-analysis/9 Aug 2023: Rocha, JJ., Arcot Jayaram, S., Stevens, TJ., Muschalik, N., Shah, RD., Emran, S., Robles, C., Freeman, M., Munro, S. -
https://www2.mrc-lmb.cam.ac.uk/groups/bienz/wp-json/wp/v2/pages/24
https://www2.mrc-lmb.cam.ac.uk/groups/bienz/wp-json/wp/v2/pages/24span class="pubJournal"J Cell Sci/span span class="pubJournalRef"strong135/strong(11)/span/li/ulnnulnlispan class="pubAuthors"Gammons M, Franco-Echevarru00eda E, Li T, Rutherford TJ, Renko M, Batters C & -
mc4604.qxd
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/current%20opinion%20micro%202001.pdf12 Nov 2001: of special interest•• of outstanding interest. 1. Mitchison TJ: Compare and contrast actin filaments andmicrotubules. ... Annu Rev Cell Dev Biol 1999, 15:63-80. 8. Desai A, Mitchison TJ: Microtubule polymerization dynamics. -
https://www2.mrc-lmb.cam.ac.uk/groups/wp-json/wp/v2/pages/2
https://www2.mrc-lmb.cam.ac.uk/groups/wp-json/wp/v2/pages/2{"id":2,"date":"2015-07-03T14:18:55","date_gmt":"2015-07-03T14:18:55","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/micro/?page_id=2"},"modified":"2023-07-14T13:59:44","modified_gmt":"2023-07-14T13:59:44","slug":"sample-page","status":"publish", -
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/wp-json/wp/v2/pages/9
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/wp-json/wp/v2/pages/9374(6573):eabk0410. doi: 10.1126/science.abk0410. Epub 2021 Dec 10. PMID: 34882480./pnpMercer TJ, Ohashi Y, Boeing S, Jefferies HBJ, De Tito S, Flynn H, Tremel S, Zhang W, ... Elife. 8:e50149. doi: 10.7554/eLife.50149. PMID:31749445/pnpTakeda AJ, Maher TJ -
Wnt signalosome assembly by dynamic head-to-tail polymerisation of…
https://www2.mrc-lmb.cam.ac.uk/groups/bienz/research-past-and-present/the-dishevelled-paradigm-assembling-the-wnt-signalosome/J Cell Sci 135(11). Gammons M, Franco-Echevarría E, Li T, Rutherford TJ, Renko M, Batters C & Bienz M (2024). -
14821680963433 1..18
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/e21600-download.pdf19 Dec 2016: For correspondence: jyl@mrc-. lmb.cam.ac.uk. Competing interests: The. authors declare that no. competing interests exist. Funding: See page 15. Received: 17 September 2016. Accepted: 14 November 2016. Published: 17 November 2016. Reviewing editor: -
FtsK in motion reveals its mechanism for double-stranded DNA…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/FtsK_Jean_2020_PNAS.pdf8 Jun 2020: FtsK in motion reveals its mechanism fordouble-stranded DNA translocationNicolas L. Jeana, Trevor J. Rutherforda, and Jan Löwea,1. aStructural Studies Division, Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 0QH, -
pnas201014665 19609..19610
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/PNAS-2010-Nogales-19609-10.pdf11 Nov 2010: Int J Biochem Cell Biol 41:323–329. 7. Koshland DE, Mitchison TJ, Kirschner MW (1988) Pole-wards chromosome movement driven by microtubuledepolymerization in vitro. -
Dynamin architecture—from monomer to polymer
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/dynaminreviewCOSBILow2010.pdf21 Oct 2010: 15. Chappie JS, Acharya S, Liu YW, Leonard M, Pucadyil TJ, Schmid SL:An intramolecular signaling element that modulates dynaminfunction in vitro and in vivo. ... 29. Pucadyil TJ, Schmid SL: Real-time visualization of dynamin-catalyzed membrane fission -
doi:10.1016/j.jbbm.2005.12.008
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/rfcloning2006%20published.pdf19 Apr 2006: 1997;25:4165–6. [7] Gibson TJ. PhD thesis. Cambridge, UK. 1984. [8] Miroux B, Walker JE. -
doi:10.1016/j.biocel.2008.08.010
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/cytomotive2008Lowe.pdf17 Sep 2008: Mol Microbiol2004;52:385–98. ggert US, Mitchison TJ, Field CM. Animal cytokinesis: from parts list to mechanisms.Annu Rev Biochem 2006;75:543–66. ... microtubuleassembly. Proc Natl Acad Sci U S A 2008;105:5378–83. omberg L, Mitchison TJ. -
Cryo‐EM structure of the full‐length Lon protease from Thermus…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Lon%20Coscia%202021%20FEBS.pdf14 Nov 2021: Curr Res Struct. Biol 1, 13–20.17 Jean NL, Rutherford TJ and Lowe J (2020) FtsK in. -
15591370691369 1..30
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/elife_2019.pdf29 May 2019: For correspondence:. rhegde@mrc-lmb.cam.ac.uk. Competing interest: See. page 28. Funding: See page 28. Received: 11 March 2019. Accepted: 15 May 2019. Published: 16 May 2019. Reviewing editor: Maya. Schuldiner, Weizmann Institute,. Israel. Copyright -
early in DNA damage response and regulateRAP80 localization. Many ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/MartensSytPap07.pdf16 Oct 2009: syt. st JJ =. Using the above values for syt. sJ and tJ , we obtain 4.0= , meaning. -
Dynamic Filaments of the Bacterial Cytoskeleton
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/annrev2006.pdf19 Apr 2006: ANRV277-BI75-21 ARI 24 February 2006 2:50. RE V. I E W. S. IN. A D V A. NC. E. Dynamic Filaments of theBacterial CytoskeletonKatharine A. Michie and Jan LöweMedical Research Council Laboratory of Molecular Biology, Cambridge CB2 2QH,UK; email: -
A Polymerization-Associated Structural Switch in FtsZ That Enables…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/mBio-2017-Wagstaff-.pdf3 May 2017: A Polymerization-Associated StructuralSwitch in FtsZ That Enables Treadmillingof Model Filaments. James M. Wagstaff,a Matthew Tsim,a María A. Oliva,b Alba García-Sanchez,b. Danguole Kureisaite-Ciziene,a José Manuel Andreu,b Jan Löwea. MRC -
doi:10.1016/j.coph.2005.03.002
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/15963759.pdf12 Nov 2006: 33. Broderick DK, Di C, Parrett TJ, Samuels YR, Cummins JM,McLendon RE, Fults DW, Velculescu VE, Bigner DD, Yan H:Mutations of PIK3CA in anaplastic oligodendrogliomas, high-grade astrocytomas, and -
Evolving nature of the AP2 a-appendage hubduring clathrin-coated…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/AP2Hub_EMBO2004/AP2Praefcke2004.pdf23 Nov 2004: Evolving nature of the AP2 a-appendage hubduring clathrin-coated vesicle endocytosis. Gerrit JK Praefcke1,2, Marijn GJ Ford1,Eva M Schmid, Lene E Olesen,Jennifer L Gallop, Sew-Yeu Peak-Chew,Yvonne Vallis, M Madan Babu,Ian G Mills3 and Harvey T -
pnas201206839 17424..17429
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/23045692.pdf21 Nov 2012: midbody and function in cytokinesis. EMBO J 26(19):4215–4227.6. Lindås AC, Karlsson EA, Lindgren MT, Ettema TJ, Bernander R (2008) A unique cell. -
Features critical for membrane binding revealed by DivIVA crystal…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/emboj201099a.pdf20 May 2010: The EMBO Journal, (2010). doi:10.1038/emboj.2010.99 -
pnas201313978 4601..4610
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/pnas2013duman.pdf23 Dec 2013: Structural and genetic analyses reveal the proteinSepF as a new membrane anchor for the Z ringRamona Dumana,1, Shu Ishikawab,1, Ilkay Celikc,1, Henrik Strahlc, Naotake Ogasawarab, Paulina Troca, Jan Löwea,2,and Leendert W. Hamoenc,d,2. aMedical -
doi:10.1016/j.ceb.2004.06.009
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/MillsMcMahonAp2Review.pdf23 Nov 2004: COP and clathrin-coated vesicle budding: different pathways,common approachesHarvey T McMahon1 and Ian G Mills2. Vesicle and tubule transport containers move proteins and. lipids from one membrane system to another. Newly forming. transport -
Recognition and Degradation of Mislocalized Proteins in Health and…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/CSHL_Persp_2019.pdf8 Mar 2019: REFERENCES. Arnold A, Horst SA, Gardella TJ, Baba H, Levine MA, Kro-nenberg HM. -
CAN-11-2008 3642..3651
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/79_Basseville_A_CanRes_2012.pdf24 Sep 2015: Cell 2003;115:727–38. 26. Corcoran LJ, Mitchison TJ, Liu Q. A novel action of histone deacetylaseinhibitors in a protein aggresome disease model. -
3747_0_supp_7_1052456676
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/christian.pdf9 May 2003: Cameleon imaging of calcium transients in cultured mechanosensory neurons in Caenorhabditis elegans. Christian Frøkjær-Jensen Speciale. February 2003 Niels Bohr Institute. University of Copenhagen. 2. Table of contents Abstract. 3 Credit. 4 -
Biallelic Variants in ASNA1, Encoding a Cytosolic Targeting Factor of …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/CircGen_2019.pdf1 Dec 2019: Circ Genom Precis Med. 2019;12:e002507. DOI: 10.1161/CIRCGEN.119.002507 September 2019 397. BACKGROUND: Pediatric cardiomyopathies are a clinically and genetically heterogeneous group of heart muscle disorders associated with high morbidity and -
If you want to download entire dataset, please contact Bill Schafer.…
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/WormBehaviorDatabase.tmp.html14 Oct 2019: If you want to download entire dataset, please contact Bill Schafer. We can provide a temporal link you can used for downloading. ###############################################. Information of strain:. Gene. Strain. Allele. Chromosome. Genotype. -
elifesciences.org van den Ent et al. eLife 2014;3:e02634. DOI: ...
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/mrebdouble2014.pdf6 Jun 2014: elifesciences.org. van den Ent et al. eLife 2014;3:e02634. DOI: 10.7554/eLife.02634 1 of 22. Bacterial actin MreB forms antiparallel double filamentsFusinita van den Ent1†, Thierry Izoré1†, Tanmay AM Bharat1, Christopher M Johnson2, Jan Löwe1. -
CELL AND MOLECULAR PHYSIOLOGY Intracellular Ca2+ release via the ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/44_Ong_HL_Pflug_Arch_2007.pdf15 Feb 2007: Biochem J289 (Pt 1):71–79. 36. Zhang SL, Yu Y, Roos J, Kozak JA, Deerinck TJ, Ellisman MH,Stauderman KA, Cahalan MD (2005) STIM1 is a Ca2+ sensor thatactivates CRAC -
Four-stranded mini microtubules formed by Prosthecobacter BtubAB show …
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/PNAS-2017-Deng-E5950-8.pdf29 Dec 2017: Four-stranded mini microtubules formed byProsthecobacter BtubAB show dynamic instabilityXian Denga,1, Gero Finka,1, Tanmay A. M. Bharata, Shaoda Hea, Danguole Kureisaite-Cizienea, and Jan Löwea,2. aStructural Studies Division, Medical Research -
15211199233993 1..45
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/MreBHussain2018.pdf15 Mar 2018: For correspondence:. egarner@g.harvard.edu. †These authors contributed. equally to this work. Competing interests: The. authors declare that no. competing interests exist. Funding: See page 32. Received: 03 October 2017. Accepted: 21 February -
elifesciences.org Szwedziak et al. eLife 2014;3:e04601. DOI:…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/FtsZ_Piotr_eLife_2014.pdf31 Dec 2014: elifesciences.org. Szwedziak et al. eLife 2014;3:e04601. DOI: 10.7554/eLife.04601 1 of 22. Architecture of the ring formed by the tubulin homologue FtsZ in bacterial cell divisionPiotr Szwedziak†, Qing Wang†, Tanmay A M Bharat, Matthew Tsim, Jan -
plbi-04-09-03 1532..1548
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/SchmidBetaPaper/BetaHub.pdf31 Aug 2006: Role of the AP2 b-Appendage Hubin Recruiting Partners for Clathrin-CoatedVesicle AssemblyEva M. Schmid. 1[, Marijn G. J. Ford. 1[, Anne Burtey. 2, Gerrit J. K. Praefcke. 3, Sew-Yeu Peak-Chew. 1, Ian G. Mills. 4,. Alexandre Benmerah2. , Harvey T. -
Mediation, Modulation, and Consequences of Membrane-Cytoskeleton…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/DohertyMcMahonAnnRevBiophys08.pdf22 May 2008: ANRV343-BB37-04 ARI 24 April 2008 15:9. Mediation, Modulation,and Consequences ofMembrane-CytoskeletonInteractionsGary J. Doherty and Harvey T. McMahonMRC Laboratory of Molecular Biology, Cambridge, CB2 0QH, United Kingdom;email: -
elife.elifesciences.org MacKinnon et al. eLife 2014;3:e01483. DOI:…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/83_MacKinnon_AL_eLife_2014.pdf9 Sep 2015: elife.elifesciences.org. MacKinnon et al. eLife 2014;3:e01483. DOI: 10.7554/eLife.01483 1 of 23. An allosteric Sec61 inhibitor traps nascent transmembrane helices at the lateral gateAndrew L MacKinnon1†, Ville O Paavilainen1†, Ajay Sharma2, -
The Biogenesis of Multipass Membrane Proteins
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/CSHL_Persp_2022.pdf13 Sep 2022: The Biogenesis of Multipass Membrane Proteins. Luka Smalinskait _e and Ramanujan S. Hegde. MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom. Correspondence: rhegde@mrc-lmb.cam.ac.uk. Multipass membrane proteins contain two or -
, 130081, published 7 August 20133 2013 Open Biol. ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Open%20Biol.-2013-TakedaCombined.pdf25 Sep 2013: 130081, published 7 August 20133 2013 Open Biol. Harvey T. McMahon and David M. GloverTetsuya Takeda, Iain M. Robinson, Matthew M. Savoian, John R. Griffiths, Anthony D. Whetton, the plasma membrane and contractile ring in cytokinesis. F-BAR protein
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