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Structure of a cholinergic cell membraneNigel Unwina,1 Edited by ...
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/pnasS22.pdf4 Nov 2022: The broken yellow lines identify the well-documented ribbon of δ subunit-linked receptor dimers(14, 15, 18, 24), one of which is labeled in each leaflet to indicate the subunit ... Biophys. J. 92, 3960–3967 (2007). 24. H. W. Chang, E. Bock, Molecular -
Cryo-EM structures reveal molecular basis of human telomerase…
https://www2.mrc-lmb.cam.ac.uk/cryo-em-structures-reveal-molecular-basis-of-human-telomerase-recruitment/25 Feb 2022: Kelly Nguyen’s group in the LMB’s Structural Studies Division has determined the molecular basis of how the TPP1 and POT1 components of shelterin recruit human telomerase to telomeres and regulate the enzyme’s activity during genomic -
The age-old problem of telomere maintenance - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/the-age-old-problem-of-telomere-maintenance/24 Nov 2022: Published on. 24 November, 2022. Kelly Nguyen, a Group Leader in the LMB’s Structural Studies Division, was awarded the 2022 Eppendorf Award for Young European Investigators earlier this year. -
Venki Ramakrishnan appointed to the Order of Merit - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/venki-ramakrishnan-appointed-to-the-order-of-merit/14 Nov 2022: Appointments to the Order are in the Sovereign’s personal gift. The Order is restricted to 24 members. -
Annual LMB student, postdoc and staff prizes awarded - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/annual-lmb-student-postdoc-and-staff-prizes-awarded/24 Oct 2022: Annual LMB student, postdoc and staff prizes awarded. Published on. 24 October, 2022. -
Paul Sigler (1934 - 2000) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/paul-sigler-1934-2000/2 Nov 2022: Nature, 403, 848 (2000) by Brian Matthews. Cell, 101, 23-24 (2000) by Max Perutz. -
Pi-PEG Screen 1.5 disclaimer
https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB19.pdf28 Sep 2022: 6.45 % 1-23 PEG 600 25.65 % BICINE 75 mM 8.4 PEG 2000 MME 6.45 % 1-24 PEG 1000 22.5 % BICINE 75 mM 8.8 PEG 3000 ... 8 PEG 3000 12.9 % 1-35 PEG 200 24.15 % BICINE 75 mM 8.4 PEG 4000 10.65 % 1-36 PEG 300 21.45 % BICINE 75 mM 8.8 -
EMBO announces 2023 elections for Young Investigator Programme - MRC…
https://www2.mrc-lmb.cam.ac.uk/embo-announces-2023-elections-for-young-investigator-programme/22 Nov 2022: Manuela is now an Assistant Professor at ETH Zurich. LMB’s researchers are among 24 life scientists chosen as Young Investigators who are within their first four years as group leaders -
Pathway behind pathogenic mechanism of tuberculosis identified - MRC…
https://www2.mrc-lmb.cam.ac.uk/pathway-behind-pathogenic-mechanism-of-tuberculosis-identified/24 Jun 2022: Published on. 24 June, 2022. TNF induces mROS specifically in macrophages infected with TB mycobacteria (yellow arrows) but not in uninfected macrophages (white arrowhead) from the same zebrafish larva. -
César Milstein Lecture to be given by Uğur Şahin and Özlem Türeci -…
https://www2.mrc-lmb.cam.ac.uk/cesar-milstein-lecture-to-be-given-by-ugur-sahin-and-ozlem-tureci/19 Jul 2022: He died in Cambridge on 24 March 2002. – Uğur Şahin. -
Refactoring the genetic code to create organisms protected by a…
https://www2.mrc-lmb.cam.ac.uk/refactoring-the-genetic-code-to-create-organisms-protected-by-a-genetic-firewall/24 Oct 2022: Published on. 24 October, 2022. Refactoring the genetic code to create organisms protected by a genetic firewall. -
Mammalian clock gene Cryptochrome 1 is crucial to suprachiasmatic…
https://www2.mrc-lmb.cam.ac.uk/mammalian-clock-gene-cryptochrome-1-is-crucial-to-suprachiasmatic-nucleus-timekeeping/31 Aug 2022: These organotypic slices are ideal to investigate circadian rhythms as, when cultured ex vivo, they maintain a robust circadian rhythm over a roughly 24-hour period and in effect serve as -
Tripodi Lab
https://www2.mrc-lmb.cam.ac.uk/groups/tripodi/feed/3 May 2022: https://www2.mrc-lmb.cam.ac.uk/groups/tripodi Space & Motion Tue, 24 Nov 2020 14:35:31 0000 en-GB hourly 1 ... tripodi/2020/11/24/chomsky-and-the-platypus/ https://www2.mrc-lmb.cam.ac.uk/groups/tripodi/2020/11/24/chomsky-and-the-platypus/#respond matt Tue -
Donald Caspar (1927 – 2021) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/donald-caspar-1927-2021/5 Jan 2022: Cold Spring Harbor Symposia on Quantitative Biology XXVII: 1-24, 1962. Primary Sidebar. -
Pi-PEG Screen 1.5 disclaimer
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/WWWrobots/LMB%20plates/LMB19b-Pi-PEG_Screen_1.5_disclaimer.pdf27 Sep 2022: 6.45 % 1-23 PEG 600 25.65 % BICINE 75 mM 8.4 PEG 2000 MME 6.45 % 1-24 PEG 1000 22.5 % BICINE 75 mM 8.8 PEG 3000 ... 8 PEG 3000 12.9 % 1-35 PEG 200 24.15 % BICINE 75 mM 8.4 PEG 4000 10.65 % 1-36 PEG 300 21.45 % BICINE 75 mM 8.8 -
PNAS202120006_proof
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/pnas%20Lee%202022.pdf18 Dec 2022: Edited by James Berger, Johns Hopkins Medical Institute, Baltimore, MD; received November 2, 2021; accepted February 24, 2022. ... However, the molecular basis for this extraordinary motoractivity remains enigmatic, despite a significant number of -
Asgard archaea shed light on the evolutionary origins of the…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Hatano%20Nat%20Comms%202022.pdf13 Jun 2022: Nature Communications, doi:10.1038/s41467-022-30656-2 -
Mechanism of signal sequence handover from NAC to SRP on ribosomes…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Science_2022.pdf27 Feb 2022: S15), which suggests thatformation of the SRP•SR complex will displaceNAC from SRP at the ER membrane (22–24).The direct interaction of the UBA domain ofNAC with SRP raises questions ... Adv. 7, eabg0942 (2021).24. K. Kobayashi et al., Science 360, -
9780470015902.a0029223
https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-content/uploads/sites/32/eLS-review_Greger.pdf1 Mar 2022: In contrast to LTP and LTD, whichare usually expressed within one hour, these adaptations requirearound 24–48 h, and therefore occur at much slower timescales.In addition, homeostatic scaling is less -
The Function, Structure, and Origins of the ER Membrane Protein…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Annual_Rev_Biochem_2022.pdf11 Apr 2022: Most membrane proteins contain more than one TMD, either within the same polypeptideor as part of obligate complexes with the TMDs of other membrane proteins (2, 24).
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