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University of Cambridge AWERB Handbook Version 6.6 2nd March ...
https://www.ubs.admin.cam.ac.uk/system/files/public/02.03.2021_awerb_handbook_6.6_external.pdf3 Mar 2021: University of Cambridge AWERB Handbook Version 6.6 2nd March 2021. 0. Advice based on Animals (Scientific Procedures) Act 1986. As reviewed and transposed 1 January 2012 and Amended 1 January 2013. University Biomedical Services. Table of Contents. -
Development of Molecular Imaging and Theranostic Agents for Cancer…
https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_molecular_imaging_and_theranostic_agents_for_cancer_and_inflammation_non-technical_s_redacted.pdf30 Apr 2024: Downloaded: 9:17pm, 25 Apr 2024 Page 5 of 9. subdued behaviour which persists for 24 h and cannot be ameliorated by minor veterinary interventions, will be humanely killed before the -
Neuronal circuit mechanisms underlying cognitive memory judgements…
https://www.ubs.admin.cam.ac.uk/system/files/public/neuronal_circuit_mechanisms_underlying_cognitive_memory_judgements_non-technical_summary_redacted.pdf30 Apr 2024: A typical study lasts between 12-24 months during which time a marmoset may receive approx. ... Such effects typically resolve within 2 hours but can extend to approximately 24 hours. -
PPL number: | Granted: 21 Aug 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_role_of_humoral_immunity_in_tissue-specific_immune_responses_in_health_and_disease_redacted.pdf20 Aug 2021: PPL number: | Granted: 21 Aug 19 | Amended: 25 Nov 20 | Expires: 21 Aug 24. ... Species- Mouse. 10000 over 5 years. Predicted harms. PPL number: | Granted: 21 Aug 19 | Amended: 25 Nov 20 | Expires: 21 Aug 24. -
PPL number: | Granted: 24 May 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_influencing_mammalian_digit_tip_regeneration_redacted.pdf18 Jun 2021: This project will aim to. PPL number: | Granted: 24 May 21 | Expires: 24 May 26. ... Why were they not suitable? PPL number: | Granted: 24 May 21 | Expires: 24 May 26. -
PPL number: | Granted: 09 Sep 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/the_integrated_stress_response_in_respiratory_disease_nts_redacted.pdf13 Sep 2021: drug administration and will be monitored regularly for signs of adverse effects within 24 hours of administration, e.g. ... For blood sampling, no more than 10% of total blood volume in 24 hours and 15% of total blood volume in any 28 day period. -
Neural, physiological and behavioural mechanisms underlying cognition …
https://www.ubs.admin.cam.ac.uk/system/files/public/neural_physiological_and_behavioural_mechanisms_underlying_cognition_and_emotion_non-technical_sum_redacted.pdf30 Apr 2024: A typical study lasts between 12-24 months during which time an animal may receive approx. ... Such effects typically resolve within 3 hours but can extend to approximately 24 hours. -
PPL number: | Granted: 18 Nov 20 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/papillomavirus_transmission_infection_and_lesion_formation_nts_redacted.pdf19 Aug 2021: The PV infection protocol (protocol 6) is estimated to require a maximum of 1000 mice (24 mice per experiment, for 50 experiments) over 5 years. -
PPL number: | Granted: 02 Feb 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/ageing_and_therapy_in_mouse_models_for_neurodegenerative_diseases_redacted_0.pdf18 Jun 2021: Animals undergoing surgical procedures will experience transient discomfort after surgery, however these animals will fully recover in less than 24 hours with no lasting effect on their general well being. ... Mild 70%. Moderate 24%. Severe 6%. PPL number -
Concordat on Openness on Animal Research in the UKAnnual ...
https://www.ubs.admin.cam.ac.uk/sites/www.ubs.admin.cam.ac.uk/files/concordat-on-openness-annual-report-2023.pdf15 Nov 2023: Concordat on Openness on Animal Research in the UKAnnual Report 2023. H. Hobson and H. Ramchandani. Contents. Foreword 1. Executive summary 2. Introduction 10. About this report 18. PART 1: PROGRESS IN OPENNESS ON ANIMAL RESEARCH IN THE UK 20. -
Investigating the niche of mucosal parasitic nematodes and their…
https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_niche_of_mucosal_parasitic_nematodes_and_their_interactions_with_their_hosts_non_redacted.pdf30 Apr 2024: 2) Labouring breathing on days 2-4 of hookworm infection, which resolves in 24 hours. -
PPL number: | Granted: 20 Nov 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/cell_competition_and_the_dynamics_of_tumour_development_in_epithelial_tissues_nts_redacted.pdf20 Aug 2021: PPL number: | Granted: 20 Nov 19 | Amended: 18 Dec 20 | Expires: 20 Nov 24. ... What's the aim of this project? PPL number: | Granted: 20 Nov 19 | Amended: 18 Dec 20 | Expires: 20 Nov 24. -
PPL number: | Granted: 05 May 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/safety_efficacy_and_immunogenicity_of_regenerative_cellular_therapies_redacted.pdf18 Jun 2021: In such cases, the animals will be culled if these clinical signs do not respond to treatment (such as high energy and easily digestible diet) and persist for up to 24 -
AWERB Standing Minutes 28th February 2024_Redacted
https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_280224_redacted.pdf30 Apr 2024: 4. Minutes of the AWERB sub-standing committee 10/01/24 The minutes were noted. ... 5. Minutes of the AWERB 3Rs Committee 03/01/24 The minutes were noted. -
Environmental and placental contributions to pregnancy and life-long…
https://www.ubs.admin.cam.ac.uk/system/files/public/environmental_and_placental_contributions_to_pregnancy_and_life-long_health_non-technical_summary_redacted.pdf29 Apr 2024: Any mouse displaying intermittent hunching or abnormal stance or reduced activity for a period of time not to exceed 24 hours, will be humanely killed. • -
Remodelling of stem cells and niche cells from development and…
https://www.ubs.admin.cam.ac.uk/system/files/public/remodelling_of_stem_cells_and_niche_cells_from_development_and_regeneration_to_disease_non-technic_redacted.pdf30 Apr 2024: Samples will be collected after humanely killing mice at different ages from birth and up to 24 months of age. -
AWERB Standing Minutes 27th March 2024
https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_270324_redacted.pdf30 Apr 2024: 3. Minutes of last meeting 28/02/24 The minutes were approved. 4. ... 9. List items of note None Date of next meeting: 24/04/2024. -
PPL number: | Granted: 12 Jun 20 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/biobehavioural_basis_of_vulnerability_to_impulsivecompulsive_spectrum_disorders_-_optimisation_and_redacted.pdf19 Aug 2021: humans, these signs wear off rapidly (within 24 to 48 hours). ... Thus, of all the 48 rats (24 from a standard condition, 24 from an enriched environment) trained to self-administer cocaine for over 80 days in this experiment, 6 became addicted -
PPL number: | Granted: 02 Mar 21 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_the_regulation_of_fat_mass_and_its_association_with_metabolic_disease_redacted.pdf18 Jun 2021: Page 4 of 8. These mice would then be group housed in their home cages while being supplied with a regular diet or a high fat diet for 24 weeks. -
AOC Minutes 22nd September 2023
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_220923_redacted.pdf14 May 2024: e. The IAT Congress 24 CPD application forms went out a few weeks ago with a closing date of the 13th of October. -
PPL number: | Granted: 08 Jul 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/regenerative_neuroimmunology_applied_to_progressive_multiple_sclerosis_research_nts_redacted.pdf13 Sep 2021: Mice aged past this point (up to 24 months) may develop health problems due to their old age. -
PPL number: | Granted: 28 Jun 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/epithelial_stem_cell_behaviour_away_from_homeostasis_translational_relevance._nts_redacted.pdf13 Sep 2021: Samples will be collected after humanely killing mice at different ages from birth and up to 24 months of age. -
AWERB Standing Minutes 24th January 2024
https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_240124_redacted.pdf30 Apr 2024: Page 1 of 3. Minutes. Date Wednesday, 24/01/2024 Time 1pm. To Standing Committee At Virtual, MS Teams. ... Subject AWERB Standing Committee Our Ref Doc.UBS.AWERB.24.01.2024. In attendance:. Scientists in attendance for 1a) Core, 1b) Core & 1c) Core -
PPL number: | Granted: 10 May 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/defining_the_role_of_the_senescent_cells_upon_the_cancer_and_pre-malignant_microenvironment_redacted.pdf18 Jun 2021: Anaesthesia will last for less than 2 hours; it may be repeated, but not more than twice in a 24 hour period.
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