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PII: 0896-6273(95)90037-3
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/neuron95.pdf4 May 2004: Number of Receptors Phase Residual" Weight in Final. scFv35 Film number 4280 3560 23.5 0.18 Film number 4282 4360 24.2 0.23 Film number 4295 4820 16.1 ... Biochemistry 24, 1212- 1221. -
53091 361..366
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/McMahon01020.pdf3 Dec 2004: 24). Thus our experiments point to a pioneering role forepsin in vesicle budding as it provides both a driving force and a linkbetween membrane invagination, clathrin polymerization and AP2complex recruitment. ... beta 2-adaptin appendage domain. EMBO J. -
Tutorial 4: Statistical Theory;Why is the Gaussian Distribution so ...
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/tutorials/statistical_theory_why_is_the_gaussian_distribution_so_popular_answers.pdf25 Mar 2014: If X Bin(100, 0.4) then E(X) = 40 and V ar(X) = 24. ... 8. pnorm(35,40,sqrt(24)). Answer: 0.154 (3sf). Statistical Theory; Why is the Gaussian Distribution so popular? -
The EMBO Journal Vol.18 No.9 pp.2364–2371, 1999 Tubulin-like…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/EMBO%20paper%201999%20FtsZ.pdf20 Apr 1999: All four calculationsproduced the same filament arrangement. After two cycles of unbendingand correction for the contrast transfer function, amplitudes and phasesfrom 24 images were merged. ... FtsZ sheet structure. and schematic plots of protein -
2623.tif
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/jcb90.pdf23 Jan 2012: glycine receptors (for recent reviews, see references 5, 7, 24, 33). -
TTC5 mediates autoregulation of tubulin via mRNA degradation
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2019.pdf19 Nov 2019: another TTC5 function (22–24), because the effects were not rescued by two unrelated point mutants of TTC5 that perturb autoregulation by different mechanisms. ... Mol. Cell 8, 71–84 (2001). doi:10.1016/S1097-2765(01)00277-5 Medline. 24. X. Hu, R. -
15591370691369 1..30
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/elife_2019.pdf29 May 2019: doxycycline, then analyzed 24 hr later by fluorescent microscopy. Doxycycline withdrawal for 24 hr limited the amount of reporter mRNA in cells to. ... Figure 5D and Figure 5—figure supplement 1C). Only a 24 kD band matching the size of TMED. -
FigS1
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/SchmidBetaPaper/BetaHubSup.pdf7 Sep 2006: AP180(27), Eps15(6). Dynamin1,2,3 (89,30,24), Amph1(24). Eps15R(52), AP180(5), Dynamin1(1). Amph1(15), Eps15R(2). Amph2(40), Epsin1(1). -
Features critical for membrane binding revealed by DivIVA crystal…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/emboj201099a.pdf20 May 2010: 21.7) 24.1 (ano. 14.1) 3.8 4.3 (ano. 2.5) 2.8. Phasing Se SAD Ta SAD MR I SAD MRNumber of sites 6 5 8Mean FOM -
doi:10.1016/j.molcel.2006.06.019
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Ftsk%20mc%202006.pdf12 Aug 2006: with a FEI F20 microscope at 62,0003 magnification with 24 to 25. -
Insight 1 Dec McMahon NS
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/NatureReview2005.pdf4 Jan 2006: EMBO J. 24, 1537–1545 (2005). 25. Cremona, O. et al. Essential role of phosphoinositide metabolism in synaptic vesiclerecycling. ... Structure of the Sec23/24-Sar1 pre-budding complexof the COPII vesicle coat. Nature 419, 271–277 (2002). -
M410_8e 231..235
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Dynamin.pdf6 Mar 2001: 24. Vallis, Y., Wigge, P., Marks, B., Evans, P. R. & McMahon, H. -
Cryo-EM Model-Buildingwith Modern Coot Paul Emsley@ Ben Gurion…
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/coot-2020-nov-slac.pdf10 Nov 2020: Slide 23. Slide 24. Slide 25. Slide 26. Slide 27. Slide 28. -
Articleshttps://doi.org/10.1038/s41594-019-0196-z 1MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Burmann%202019%20NSMB.pdf4 Mar 2019: Cell 163, 1628–1640 (2015). 24. Bürmann, F. et al. Tuned SMC arms drive chromosomal loading of prokaryotic condensin. ... Curr. Biol. 21, 12–24 (2011). 27. Badrinarayanan, A., Reyes-Lamothe, R., Uphoff, S., Leake, M. -
IntroductionThe endosomal system functions as an internal…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/SNX2Cullen2005.pdf17 Jan 2006: treatment. Results were normalised againstthe amount of CD8 reaching the TGN after 24 minutes in control-treated cells, and were expressed the s.e.m. ... 9A).Compared with control cells, suppression of SNX1 led to a54.57.8% reduction in the amount of anti -
CURRICULUM VITAE
https://www2.mrc-lmb.cam.ac.uk/groups/bienz/wp-content/uploads/sites/23/BienzCV_March2024.pdf11 Apr 2024: eucaryotes. Adv Genet 24, 31-72. 17. Saari G & Bienz M (1987) The structure of the Ultrabithorax promoter. ... Drosophila embryos. EMBO J 8, 2677-2685. 24. Tremml G & Bienz M (1989b) An essential role of even-skipped for homeotic gene. -
Dissertation
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/AndyHuang.pdf6 Mar 2008: algorithm [24]. Redundant pixels on the skeleton are eliminated by thinning. ... skeleton algorithm [7, 24]. However, sometimes the binary worm body shape has an internal hole,. -
ANALYSIS Integrating molecular and network biologyto decode…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Schmid_Nature2007.pdf22 Aug 2007: 2a)7,8,23,24. 1MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 0QH, UK. ... Nature Biotechnol. 24, 1270–1278(2006). 42. Smith, C. J., Grigorieff, N. & Pearse, B. -
Supplementary Figure 1Lysophosphatidic acid acyl transferase (LPAAT)…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/GallopEndoSupFigs.pdf4 Jan 2006: 35. 24. 21. Bead. s pos. t clea. vage. Purif. ied cl. -
Crystal Structures of Bacillus subtilis Lon Protease
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/londumanjmb2010.pdf20 Jul 2010: electron microscopy data show that negativelystained images of E. coli Lon particles appearhexameric,24 although surprisingly, electron cryo-microscopy images of S. -
www.landesbioscience.com Autophagy 805 Autophagy 6:6, 805-807; August …
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/20574157.pdf2 Aug 2010: Submitted: 05/24/10. Revised: 06/03/10. Accepted: 06/03/10. Previously published online: www.landesbioscience.com/journals/autophagy/article/12577Correspondence to: Roger L. -
REPORT◥ PROTEIN HOMEOSTASIS Mechanistic basis for a moleculartriage…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2017.pdf19 Jan 2017: S5). This orthogonal system pro-duces homogeneous TA-chaperone complexesthat can be used for downstream functional as-says (24). ... 24. A. Mateja et al., Science 347, 1152–1155 (2015).25. S. M. -
doi:10.1016/j.ceb.2004.06.009
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/MillsMcMahonAp2Review.pdf23 Nov 2004: coatedvesicles. The COPII membrane-associated sec23/24 com-plex has an intrinsic curvature like that found in COPIIvesicles and thus by polymerisation this curvature will befavoured [36]. ... with Sec23/24p in vitro. Stabilises Sec23/24 complex and. -
doi:10.1016/j.jmb.2004.12.031
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/jmb05.pdf24 Jan 2005: doi:10.1016/j.jmb.2004.12.031 J. Mol. Biol. (xxxx) xx, 1–23. ARTICLE IN PRESS. Refined Structure of the Nicotinic AcetylcholineReceptor at 4 Å Resolution. Nigel Unwin. MRC Laboratory of MolecularBiology, Hills Road, CambridgeCB2 2QH, UK. -
Asgard archaea shed light on the evolutionary origins of the…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Hatano%20Nat%20Comms%202022.pdf13 Jun 2022: Nature Communications, doi:10.1038/s41467-022-30656-2 -
articles Nucleotide-dependent conformational changes in dynamin:…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Stowell_McMahon1999.pdf30 Apr 1999: Results of in vitro experiments have revealed that dynamin isable to bind and tubulate lipid membranes in the absence of anyother accessory factors23,24. ... RECEIVED 24 FEBRUARY 1999; REVISED 12 MARCH 1999; ACCEPTED 12 MARCH 1999; PUBLISHED MAY 1999. -
x16412u141
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/MaoAP180-2001.pdf17 Mar 2003: 3 246,217 67,191 99.5 (100) 24.0 (4.4) 6.4 (27.1)SeMet l3 (0.9712) 2.3 248,253 67,292 99.7 (100) 22.9 ... Neuron 24, 143–154. Schmid, S.L. (1997). Clathrin-coated vesicle formation and proteinsorting: an integrated process. -
Technician Commitment Evaluating Impact through Self-Assessment & …
https://www2.mrc-lmb.cam.ac.uk/wordpress/?wpdmdl=35486&ind=168994162466726 Jul 2023: open day to be held on 1st July 2023. Please provide a 24-month action plan, detailing future plans to ensure your organisations addresses the themes of the Technician. -
Bb9e55.qxd
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Vallis_McMahon1999.pdf21 Mar 2003: J Biol Chem 1996, 271:27979-27982. 24. Liu JP, Yajima Y, Li H, Ackland S, Akita Y, Stewart J, et al.: Molecularinteractions between dynamin and G-protein beta gamma-subunits ... Cells were plated 24 h prior to trans-fection (day 0) at a density of 1.4 -
Contrasting Membrane Interaction Mechanisms of AP180N-terminal…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Stahelin_cho2003.pdf16 Jul 2003: The coating of the L1 sensor chiphas been described in detail previously (23, 24). ... 3).On the other hand, the membrane dissociation step of periph-eral proteins can be slowed by short range specific interactionsand membrane penetration of hydrophobic -
Refined Structure of (alpha)(beta)-Tubulin at 3.5 A Resolution
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/jmb%20tubulin%20refinement.pdf3 Nov 2001: 24,pp. 255-302, Plenum Press, New York. 26. Wolf, S. G., Nogales, E., Kikkawa, M., Gratzinger,D., Hirokawa, N. & ... S. (1968). RelativisticHartree-Fock X-ray and electron scattering factors.Acta Crystallog. sect. A, 24, 390-397. -
Biol. Chem., Vol. 381, pp. 993 – 999, September/October ...
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/BiolChem%20Helical%20Tubes.pdf13 Sep 2000: Cell Struct. Funct. 24,285 – 290. Lu, C.L., Stricker, J., and Erickson, H.P. ... EMBO J. 16, 5455 –5463. Received May 24, 2000; accepted July 14, 2000. -
DOI: 10.1126/science.1135394 , 239 (2007); 317Science et al.Nabil…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17626883.pdf8 Dec 2007: Wymann, M. Zvelebil, M. Laffargue, Trends. Pharmacol. Sci. 24, 366 (2003).4. ... Chem. 276, 21544 (2001). 24. E. H. Walker, O. Perisic, C. -
bic296a
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/EberthBJ4170371.pdf24 Jan 2009: Two fragments of 24 and 22 kDaremained stable after limited trypsin cleavage for 48 h (Figure 1C;Supplementary Figure S2A, at http://www.BiochemJ.org/bj/417/bj4170371add.htm). ... J. Biol. Chem.280, 6716–6720. 24 Longenecker, K. L., Zhang, B. L., -
BIO CHEM ISTR Y Structure of the SARS-CoV-2 RNA-dependent ...
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/SARS%20polym%202021%20e2021946118.full.pdf29 Aug 2021: 1 2 3 4 5 6. 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24. ... 9, 2. 021. 24 and SI Appendix, Fig. S1B). The accumulation of shorter primer exten-sion intermediates at higher concentrations of favipiravir-RTP may indicatepremature replication -
Proc. Natl. Acad. Sci. USAVol. 94, pp. 9637–9642, September ...
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/9275175.pdf20 Apr 2002: An initial model wasbuilt using the program O (24). Noncrystallographic symmetryrestrained positional and temperature factor refinement werecarried out with the program X-PLOR. ... S. (1993) Acta Crystallogr. D 49,. 129 –147.24. Jones, T. A., Zou, J.-Y. -
doi:10.1016/j.str.2007.05.002
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/FCH02F-BARHenne07.pdf2 Jun 2007: Coomassie-stained gel. P, pellet; S, superna-. tant. At protein concentrations above 24 mM,. ... For cryocooling, crystals were transferred stepwise into the crystalliza-. tion condition supplemented with up to 24% glycerol. -
The current approach to initial crystallization screening of proteins …
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Gorrec_undersamplid_2013.pdf14 May 2013: Appl. Cryst. 24, 409–411.Kimber, M. S., Vallee, F., Houston, S., Necakov, A., Skarina, T., Evdokimova,. -
DOI: 10.1126/science.1184429 , 1638 (2010); 327Science et al.Simon…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/20339072.pdf2 Aug 2010: 9, 1142 (2007).23. C. Liang et al., Nat. Cell Biol. 10, 776 (2008).24. ... 1), factorially manipulatedpredator access and soil fertility, and monitoredplant biomass and populations of the potentherbivore Aphis nerii (Aphididae, Hemiptera), aspecialist on -
LETTERS Structural basis for selective recognition of ESCRT-IIIby the …
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17928861.pdf8 Dec 2007: e. 0 40 60 80 100200.20. 0.22. 0.24. 0.26. 0.28. 0.30. ... EMBO J. 24,3658–3669 (2005). 18. Babst, M., Katzmann, D. J., Estepa-Sabal, E. -
3747_0_supp_7_1052456676
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/christian.pdf9 May 2003: 24. individual yellow and cyan emission intensities. The ratio faithfully reflects reciprocal. -
Amos&Schlieper.indd
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Amos%26Schlieper.pdf16 Nov 2005: MICROTUBULES AND MAPs. By LINDA A. AMOS AND DANIEL SCHLIEPERMRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK. I. IntroductionII. Microtubule Structure A. Subunit Lattices B. Atomic Structure of the Protofilament C. Atomic -
Four-stranded mini microtubules formed by Prosthecobacter BtubAB show …
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/PNAS-2017-Deng-E5950-8.pdf29 Dec 2017: For BtubAB filament reconstruction, 1,394 movies were usedfrom two separate 24-h microscope sessions. ... S1). For BtubABC filament reconstruction, 6,105 movies were used from fourseparate 24-h microscope sessions. -
REPORT◥ PROTEOSTASIS UBE2O is a quality control factor fororphans ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2017b.pdf4 Aug 2017: In most cellsunder normal conditions, orphan proteins prob-ably represent the predominant clients for qua-lity control given the large number of abundantmultiprotein complexes (23, 24), the challengesof precisely matching expression ... N. J. Krogan et al -
Mediation, Modulation, and Consequences of Membrane-Cytoskeleton…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/DohertyMcMahonAnnRevBiophys08.pdf22 May 2008: sona. l use. onl. y. ANRV343-BB37-04 ARI 24 April 2008 15:9. ... l use. onl. y. ANRV343-BB37-04 ARI 24 April 2008 15:9. Endocyticevents. -
Qrb1300006 1..40
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/qrb13.pdf30 Jul 2013: Transition to open-channel form 23. 5.1. Introduction 23. 5.2. Spray-freeze-trapping experiments 24. -
No Job Name
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/vandenent2008ftsq.pdf4 Mar 2008: FtsQ is a bitopic membraneprotein of 31 kDa (Robinson et al., 1984), consisting of ashort cytoplasmic tail (residues 1–24), a transmembraneregion (25–49) and a periplasmic domain of approximately226 residues -
KS_2012_A5_Meeting.indd
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/conferences/2012_A5_Save_the_Date.pdf19 Sep 2011: Late-Breaking Abstract:October 24, 2011. Early Registration:November 21, 2011. Deadlines. late-breaking research • cross-disciplinary collaboration • networking opportunities • peer-reviewed meeting programs. -
The Structure of a Tunicate C-type Lectin from Polyandrocarpa…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/10398588.pdf7 Jul 1999: Joint CCP4 and ESF-EACBM Newsletter for Protein Crystallography, 33, 22-24. Gabius, H. ... Biophys.Biomol. Struct. 24, 551-577. Sambrook, J., Fritsch, E. F. & Maniatis, T. -
validation-tutorial.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/tutorial/validation-tutorial.pdf24 Oct 2017: Tutorial: Validation with Coot. CSHL 2017. October 24, 2017. 1 Preamble.
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