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14 May 2024: Highlights of AWERB Standing meeting 24/05/23 None. 10. Highlights of January AOC meeting 19/05/23 None.

30 Apr 2024: The neural crest cells are formed over approximately 24 hours. This means that we can put the intact embryo under a specialised microscope and can easily image the whole process of

30 Apr 2024: PPL number: | Granted: 20 Apr 23 | Amended: 24 Aug 23 | Expires: 20 Apr 28. ... be. PPL number: | Granted: 20 Apr 23 | Amended: 24 Aug 23 | Expires: 20 Apr 28.

20 Aug 2021: PPL number: | Granted: 07 Aug 19 | Expires: 06 Aug 24.

13 Sep 2021: PPL number: | Granted: 03 Jul 19 | Amended: 09 Sep 21 | Expires: 14 Jan 24. ... Contains severe procedures. Objectives and benefits. PPL number: | Granted: 03 Jul 19 | Amended: 09 Sep 21 | Expires: 14 Jan 24.

30 Apr 2024: Tumour organoids do have more of. PPL number: | Granted: 03 Jan 24 | Expires: 03 Jan 29. ... Animals that enter experimental. PPL number: | Granted: 03 Jan 24 | Expires: 03 Jan 29.

30 Apr 2024: In summary, mice will be aged up to the age of 24 months. ... Some genetically altered mice will be maintained for ageing until they reach a maximum of 24 months of age.

30 Apr 2024: This can benefit a wider scientific community. PPL number: | Granted: 08 Mar 24 | Expires: 08 Mar 29. ... Mice. Mild Severity - 100%. Moderate severity - 0%. Rats. PPL number: | Granted: 08 Mar 24 | Expires: 08 Mar 29.

18 Sep 2015: 5.1 Accommodation specifications 22. Section 1, Chapter 3: Rabbits 24 – 261 Accommodation specifications 24. ... 1.1 Doe plus litter 241.2 Breeding animals and post-weaned stock 241.3 Rabbits being used in procedures 24.

14 May 2024: If an animal does not improve within. 72 hours then they may not be euthanised for a further 24 hours.

30 Apr 2024: PPL number: | Granted: 25 Jan 23 | Amended: 24 Jan 24 | Expires: 25 Jan 28. ... lung. PPL number: | Granted: 25 Jan 23 | Amended: 24 Jan 24 | Expires: 25 Jan 28.

29 Apr 2024: PPL number: | Granted: 14 Jan 22 | Amended: 24 Jan 22 | Expires: 14 Jan 27. ... with. PPL number: | Granted: 14 Jan 22 | Amended: 24 Jan 22 | Expires: 14 Jan 27.

30 Apr 2024: Production of the candidate imaging agent. PPL number: | Granted: 16 Feb 24 | Expires: 16 Feb 29. ... Mice. Non-recovery: 64%. Mild: 36%. Moderate: 0%. Severe: 0%. Rats. PPL number: | Granted: 16 Feb 24 | Expires: 16 Feb 29.

20 Aug 2021: What's the aim of this project? PPL number: | Granted: 18 Nov 19 | Expires: 18 Nov 24. ... Refinement. PPL number: | Granted: 18 Nov 19 | Expires: 18 Nov 24.

13 Sep 2021: PPL number: | Granted: 31 Jan 19 | Amended: 16 Jul 21 | Expires: 30 Jan 24. ... Contains severe proceduresRequired at inspector’s discretion. PPL number: | Granted: 31 Jan 19 | Amended: 16 Jul 21 | Expires: 30 Jan 24.

30 Apr 2024: Companion animal immunoglobulin. PPL number: | Granted: 10 Apr 24 | Expires: 10 Apr 29. ... Substances will be. PPL number: | Granted: 10 Apr 24 | Expires: 10 Apr 29.

30 Apr 2024: Mice that are immunised can show mild signs of discomfort that should last no more than 24 hours.

30 Apr 2024: This allows unsuitable drugs to be. PPL number: | Granted: 24 Mar 22 | Expires: 24 Mar 27. ... Blood samples are usually small in volume and are. PPL number: | Granted: 24 Mar 22 | Expires: 24 Mar 27.

30 Apr 2024: PPL number: | Granted: 18 Apr 23 | Amended: 28 Mar 24 | Expires: 18 Apr 28. ... Reduction. PPL number: | Granted: 18 Apr 23 | Amended: 28 Mar 24 | Expires: 18 Apr 28.

30 Apr 2024: Subject AWERB 3Rs Committee Our Ref Doc.AWERB.3Rs.03.01.24. AWERB 3Rs Committee :. In attendance:. Minutes – Apologies:. 1. Minutes. The minutes of the meeting held on the 6th December

30 Apr 2024: Nonetheless, we will closely monitor the fish to detect any signs of suffering and stress during the procedure and in 24 hours following the procedure. ... This will require a maximum of 1800 animals. PPL number: | Granted: 29 Feb 24 | Expires: 28 Feb 29.

30 Apr 2024: PPL number: | Granted: 21 Mar 24 | Expires: 21 Mar 29. ... Over the period 24-96h, animals may show reduced appetite for food and water, which is expected to result in minor weight loss (less than 5-10% of their pre-operative

29 Apr 2024: Haem A, Haem B, and Glanzmann mice sometimes have surface bleeds that can be treated, and these usually resolve over 24 hours. ... Sometimes Haem A mice can have bleeds from the ears that also can, in most cases, resolve within 24 hours.

30 Apr 2024: These animals will be killed unless there are signs of recovery within 24 hours.

20 Aug 2021: PPL number: | Granted: 28 Oct 19 | Expires: 28 Oct 24.

13 Sep 2021: PPL number: | Granted: 29 Jan 19 | Amended: 03 Sep 21 | Expires: 28 Jan 24. ... Contains severe proceduresRequired at inspector’s discretion. PPL number: | Granted: 29 Jan 19 | Amended: 03 Sep 21 | Expires: 28 Jan 24.

20 Aug 2021: For laparoscopic procedures:. Potential adverse effects. PPL number: | Granted: 01 Apr 21 | Expires: 01 Apr 24. ... By combining as. PPL number: | Granted: 01 Apr 21 | Expires: 01 Apr 24.

30 Apr 2024: We have published these findings in animal welfare journals. However, 24% of animals will need to experience more than three shocks, with the maximum number of footshocks that will be delivered ... Moderate: 76%. Severe: 24%. What will happen to animals

30 Apr 2024: subcutaneous 20ml/kg 2 24. Exceptions to this would be thioglycollate IP, which needs to be given in 1ml (standard practice), and the HDTV injection.

20 Aug 2021: All surgical. PPL number: | Granted: 20 Nov 19 | Expires: 20 Nov 24. ... Reduction. PPL number: | Granted: 20 Nov 19 | Expires: 20 Nov 24.

13 Sep 2021: PPL number: | Granted: 10 Apr 19 | Amended: 16 Jul 21 | Expires: 09 Apr 24.

30 Apr 2024: PPL number: | Granted: 03 Jul 23 | Expires: 03 Jul 28. Downloaded: 9:27pm, 25 Apr 2024 Page 2 of 11. Objectives and benefitsDescription of the projects objectives, for example the scientific unknowns or clinical orscientific needs it's addressing.

30 Apr 2024: Similarly, researchers found that there was a 24% increased risk of depression, which increased the number of depressed individuals from an average of 10/1,000 to 14/1,000 in ... Since this is an experimental modelling of a viral infection, the female

19 Aug 2021: PPL number: | Granted: 24 Sep 20 | Amended: 05 Feb 21 | Expires: 24 Sep 25. ... Objectives and benefits. PPL number: | Granted: 24 Sep 20 | Amended: 05 Feb 21 | Expires: 24 Sep 25.

30 Apr 2024: PPL number: | Granted: 03 Feb 22 | Amended: 14 Mar 24 | Expires: 03 Feb 27. ... Ascites may occur. PPL number: | Granted: 03 Feb 22 | Amended: 14 Mar 24 | Expires: 03 Feb 27.

30 Apr 2024: Even with timely dialysis, the death rates in patients with kidney failure vary from 20% to 50% over 24 months.

29 Apr 2024: In such cases, the animals will be culled if these clinical signs do not respond to treatment (such as high energy and easily digestible diet) and persist for up to 24

13 Sep 2021: If no improvement was shown within 24 hours, then the animal would be humanely killed.

20 Aug 2021: Theories and ideas can. PPL number: | Granted: 19 Nov 19 | Expires: 19 Nov 24. ... Page 8 of 11. PPL number: | Granted: 19 Nov 19 | Expires: 19 Nov 24.

19 Aug 2021: 4. For moderate levels of prenatal hypoxia (below 13% oxygen), rats will first be put into the chamber at normal oxygen levels (21%) for 24 hours, and then oxygen will be ... reduced slowly (over another 24-hour period) to avoid shock.

3 Mar 2021: University of Cambridge AWERB Handbook Version 6.6 2nd March 2021. 0. Advice based on Animals (Scientific Procedures) Act 1986. As reviewed and transposed 1 January 2012 and Amended 1 January 2013. University Biomedical Services. Table of Contents.

29 Apr 2024: As the mice are checked daily, at most, a mouse would experience paralysis for no more than 24 hours.

13 Sep 2021: PPL number: | Granted: 25 Mar 21 | Amended: 24 Aug 21 | Expires: 25 Mar 26. ... Objectives and benefits. PPL number: | Granted: 25 Mar 21 | Amended: 24 Aug 21 | Expires: 25 Mar 26.

30 Apr 2024: Downloaded: 9:17pm, 25 Apr 2024 Page 5 of 9. subdued behaviour which persists for 24 h and cannot be ameliorated by minor veterinary interventions, will be humanely killed before the

30 Apr 2024: A typical study lasts between 12-24 months during which time a marmoset may receive approx. ... Such effects typically resolve within 2 hours but can extend to approximately 24 hours.

20 Aug 2021: PPL number: | Granted: 21 Aug 19 | Amended: 25 Nov 20 | Expires: 21 Aug 24. ... Species- Mouse. 10000 over 5 years. Predicted harms. PPL number: | Granted: 21 Aug 19 | Amended: 25 Nov 20 | Expires: 21 Aug 24.

18 Jun 2021: This project will aim to. PPL number: | Granted: 24 May 21 | Expires: 24 May 26. ... Why were they not suitable? PPL number: | Granted: 24 May 21 | Expires: 24 May 26.

13 Sep 2021: drug administration and will be monitored regularly for signs of adverse effects within 24 hours of administration, e.g. ... For blood sampling, no more than 10% of total blood volume in 24 hours and 15% of total blood volume in any 28 day period.

30 Apr 2024: A typical study lasts between 12-24 months during which time an animal may receive approx. ... Such effects typically resolve within 3 hours but can extend to approximately 24 hours.

19 Aug 2021: The PV infection protocol (protocol 6) is estimated to require a maximum of 1000 mice (24 mice per experiment, for 50 experiments) over 5 years.