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If you want to download entire dataset, please contact Bill Schafer.…
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/WormBehaviorDatabase.tmp.html14 Oct 2019: hermaphrodite. young adult. 30minutes. 2011-02-24 16:06:02. OP50. 627nm. 22C. No treatment. ... hermaphrodite. young adult. 30minutes. 2011-02-24 16:36:26. OP50. 627nm. 22C. No treatment. -
Activation of GCN2 by the ribosomal P-stalk
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/PNAS_2019.pdf7 Mar 2019: Yeast GCN2 forms aconstitutive dimer even in the absence of activation, principallythrough the CTD (24, 25). ... This lack of clarity was further con-founded by a more recent report that, unlike yeast, mouseGCN2 does not form a stable complex that -
Mechanism of ribosome stalling during translation of a poly(A) tail
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/NSMB_2019.pdf25 Nov 2019: The stalled ribosome triggers the ‘no-go’ or ‘nonstop’ pathways of mRNA decay10,13,17,18, nascent protein degra-dation via ribosome-associated quality control12,19–23 and ribosome ... 24,25,30,31). A second mechanism involves detecting the -
The structure of bactofilin filaments reveals their mode of membrane…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Deng2019Natmicro.pdf26 Aug 2019: e (R. U). Time (s). WT. 0. 100. 200. 300. –1 10 14 24. -
The ER membrane protein complex promotes biogenesis of sterol-related …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/JCS_2019.pdf18 Jan 2019: At 24 h post transfection, cellswere treated with MG132 (5 µg/ml) or DMSO (vehicle control) for 8 h andanalysed by flow cytometry. -
Biallelic Variants in ASNA1, Encoding a Cytosolic Targeting Factor of …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/CircGen_2019.pdf1 Dec 2019: due to impaired ASNA1-mediated nuclear targeting.24 Though emerin staining showed apparently normal localization of the protein in our patients, it did reveal the characteristic abnormal nuclear morphology previously described ... J Cardiovasc Dev Dis. -
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https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/elife_2019.pdf29 May 2019: doxycycline, then analyzed 24 hr later by fluorescent microscopy. Doxycycline withdrawal for 24 hr limited the amount of reporter mRNA in cells to. ... Figure 5D and Figure 5—figure supplement 1C). Only a 24 kD band matching the size of TMED. -
TTC5 mediates autoregulation of tubulin via mRNA degradation
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2019.pdf19 Nov 2019: another TTC5 function (22–24), because the effects were not rescued by two unrelated point mutants of TTC5 that perturb autoregulation by different mechanisms. ... Mol. Cell 8, 71–84 (2001). doi:10.1016/S1097-2765(01)00277-5 Medline. 24. X. Hu, R. -
Articleshttps://doi.org/10.1038/s41594-019-0196-z 1MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Burmann%202019%20NSMB.pdf4 Mar 2019: Cell 163, 1628–1640 (2015). 24. Bürmann, F. et al. Tuned SMC arms drive chromosomal loading of prokaryotic condensin. ... Curr. Biol. 21, 12–24 (2011). 27. Badrinarayanan, A., Reyes-Lamothe, R., Uphoff, S., Leake, M. -
Cryo‐EM structure of the MinCD copolymeric filament from Pseudomonas…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Szewczak-Harris_et_al-2019-FEBS_Letters.pdf22 Jul 2019: binds the conserved C-terminal tail domain of FtsZ. and, importantly, binds MinD [24,25]. ... Curr Biol. 18, 235–244.24 Cordell SC, Anderson RE and Lowe J (2001) Crystal.
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