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The structure of human thyroglobulin
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/TG_Nature2020.pdf31 Jan 2020: Replacing all acceptor. tyrosines (Y) with phenylalanines (F) prevents hormone formation (4 acceptor residues: 24, 2573, 2766 and 1310). ... Eur. J. Endocrinol. 138, 227–231 (1998). 24. Dunn, J. T., Kim, P. -
FtsK in motion reveals its mechanism for double-stranded DNA…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/FtsK_Jean_2020_PNAS.pdf8 Jun 2020: This arrangementis reminiscent of the single spiral staircases observed in ring-shaped helicases (24). ... orienting the FtsK translocase. EMBO J. 24, 3770–3780 (2005).10. S. Bigot, O. -
Identifying proteins bound to native mitotic ESC chromosomes reveals…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Djeghloul%20Nat%20Camms%202020.pdf11 Aug 2020: 23.4 4.1, 43.6 6.9 µm2 respectively) or Eed/ (24.3 4.5,42.2 4.7 µm2, respectively) ESCs are significantly larger thanequivalent chromosomes isolated from WT ... 24 %. 70 %. async m-arrested. coun. t. PI intensity. Cardiomyocytes. -
16001658465475 1..36
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Collier_2020_elife-59560-v1.pdf15 Sep 2020: For correspondence:. jyl@mrc-lmb.cam.ac.uk (JL);. ashley.nasmyth@bioch.ox.ac.uk. (KAN). †These authors contributed. equally to this work. Competing interests: The. authors declare that no. competing interests exist. Funding: See page 33. Received: -
An intramembrane chaperone complex facilitates membrane protein…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2020/09/Nature_2020.pdf17 Aug 2020: Cell 170, 298–311.e20 (2017). 24. Stein, K. C., Kriel, A. & Frydman, J. ... After 24 h, transfected cells were selected for 48 h with 1 μg ml1 puromycin then trypsinized and diluted into 96-well plates at a concentration of 0.5 cells per -
15919734904046 1..30
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2020/09/eLife_2020.pdf12 Jun 2020: α-FLAG. Nat. IPα-FLAG. α-EMC1. EMC1. 1 x 3. Lysate. – – –. 23 24 25 26 23 23. C. EMC3. amb:. detergentmicelle. BBBBBBBBBBB. -
15955888524538 1..29
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2020/09/eLife_2020b.pdf24 Jul 2020: transgenes. was allowed for 24 hr. After additional 20 hr of doxycycline-induced expression of the stalling reporter, GFP expression was analysed by flow cytometry.
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