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News - Cambs 24
https://www2.mrc-lmb.cam.ac.uk/archive/articles/Road_named_after_legendary_scientist.pdf1 Feb 2013: Copyright 2013 Archant Regional Ltd. All rights reserved. News - Cambs 24 http://www.cambs24.co.uk/news/cambridge_road_to_be_na. -
Gisela Perutz and the LMB canteen - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/gisela-perutz-and-the-lmb-canteen/24 Jun 2013: Published on. 24 June, 2013. The history behind the LMB’s canteen. -
New mechanism in the body’s timekeeping revealed - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/new-mechanism-in-the-bodys-timekeeping-revealed/30 Apr 2013: The suprachiasmatic nucleus (SCN) is part of the body clock and individual neurons of the SCN contain their own 24-hour clock, but they operate best when connected together in their ... This provided a completely new perspective on how the circadian -
Architecture of the spliceosome active site - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/architecture-of-the-spliceosome-active-site/24 Jan 2013: Published on. 24 January, 2013. Research in the group of Kiyoshi Nagai in the LMB’s Structural Studies Division has for the first time provided detailed information on the structure and -
Three LMB scientists elected to EMBO membership - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/three-lmb-scientists-elected-to-embo-membership/24 May 2013: Published on. 24 May, 2013. Three LMB scientists, Anne Bertolotti, Ramanujan Hegde and KJ Patel have been named as newly elected members to the European Molecular Biology Organization (EMBO). -
TRIM21 senses infection and triggers immune response inside cells -…
https://www2.mrc-lmb.cam.ac.uk/trim21-senses-infection-and-triggers-immune-response-inside-cells/4 Mar 2013: New research, led by Leo James and Will McEwan from the LMB’s PNAC Division, has uncovered a previously unrecognised mechanism of intracellular pathogen -
Understanding timekeeping in an intertidal marine crustacean - MRC…
https://www2.mrc-lmb.cam.ac.uk/understanding-timekeeping-in-an-intertidal-marine-crustacean/27 Sep 2013: They were interested in whether these animals are driven by a dedicated internal tidal clock or are controlled by a system based on a modified 24-hour circadian clock. ... Indeed, 24-hour clocks permeate every aspect of terrestrial physiology and -
2013 César Milstein Lecture to be given by Scott Emr - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/2013-milstein-lecture-to-be-given-by-scott-emr/20 Sep 2013: He died in Cambridge on 24 March 2002. Primary Sidebar. Search. -
KJ Patel receives Fanconi Anemia Research Fund Award of Merit - MRC…
https://www2.mrc-lmb.cam.ac.uk/kj-patel-receives-fanconi-anemia-research-fund-award-of-merit/18 Dec 2013: This award has been given only five times in the Fund’s 24-year history, and not since 2005. -
Structure and superorganization of acetylcholinereceptor–rapsyn…
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/pnas13.pdf3 Jul 2013: 20%of the receptors showed restricted diffusion in small domains of50 nm, whereas the majority of the receptors were immobile (24).Confocal microscopy of overexpressed rapsyn in nonmuscle. ... The cross-linking of receptors by rapsyn,therefore, seems to -
MR_LMB
https://www2.mrc-lmb.cam.ac.uk/download/molecular-replacement/?wpdmdl=18799&refresh=669d2bcbb809a172157639511 Jun 2013: 24 (12) RF/TF. 3 (1) Pack. 3 (1) Refined. 307 (283) RF/TF. ... 68 (64) Pack. 24 (2) Refined. 32 (20) RF/TF. 22 (17) Pack. -
doi:10.1128/mBio.00800-13. 4(6): .mBio. Midcell DNA Translocase FtsK…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/mbio2013bisicchia.pdf23 Dec 2013: coli FtsKN used in the in vivo experiments, 24 amino acids forthe E. ... Mol. Microbiol.27:257–268. 24. Steiner W, Liu G, Donachie WD, Kuempel P. -
pnas201313978 4601..4610
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/pnas2013duman.pdf23 Dec 2013: AnezrA-null mutant forms slightly longer cells (20%) comparedwith wild-type cells (23), but an ftsA null mutant has problemsdividing and forms long filamentous cells (24). -
The current approach to initial crystallization screening of proteins …
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Gorrec_undersamplid_2013.pdf14 May 2013: Appl. Cryst. 24, 409–411.Kimber, M. S., Vallee, F., Houston, S., Necakov, A., Skarina, T., Evdokimova,. -
Qrb1300006 1..40
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/qrb13.pdf30 Jul 2013: Transition to open-channel form 23. 5.1. Introduction 23. 5.2. Spray-freeze-trapping experiments 24. -
Cooperative Recruitment of Dynamin and BIN/Amphiphysin/Rvs (BAR)…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/JBC_Meinecke2013.pdf19 Mar 2013: nexin 9 (SNX9) (23, 24). It has a BAR and an SH3 domain thatbinds to dynamin.The involvement of BAR domain proteins in dynamin activ-. ... J. Biol. Chem. 278, 46772–46781. 24. Soulet, F., Yarar, D., Leonard, M., and Schmid, S. -
Madeline Lancaster Differentiation of hESCs to Cerebral Organoids…
https://www2.mrc-lmb.cam.ac.uk/groups/lancaster/download/Differentiation-of-hESCs-to-cerebral-organoids.docx20 Sep 2013: a low cell binding 24-well plate (1-2 per well) using a cut P200 tip to carefully transfer without disrupting. -
Deubiquitinases Sharpen Substrate Discrimination during Membrane…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/82_Zhang_ZR_Cell_2013.pdf5 Aug 2013: panel) plasmids were cotransfected with a fixed. amount (100 ng) of CD4 and analyzed 24 hr later by. -
MR_LMB
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/MR_LMB.pdf11 Jun 2013: 24 (12) RF/TF. 3 (1) Pack. 3 (1) Refined. 307 (283) RF/TF. ... 68 (64) Pack. 24 (2) Refined. 32 (20) RF/TF. 22 (17) Pack. -
PowerPoint Presentation
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/ImaginingTheBrain/2014/media/Changing_Brains_The_Teenage_Brain_website.pptx2 May 2013: Sun/ Mon. Mon/ Tues. Tues/ Wed. Actogram, F 16 yrs. 0 12 24 36 48. -
, 130081, published 7 August 20133 2013 Open Biol. ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Open%20Biol.-2013-TakedaCombined.pdf25 Sep 2013: compacted by the ingressingcleavage furrow (figure 2e, wild-type, 16 – 24 min; electronicsupplementary material, movie S3). ... GFP alone, the cleavage furrowstarted to ingress within 4 min after anaphase onset at2.24 mm min – 1 (s.e.m. -
Expression, purifica0on, characteriza0on, and crystalliza0on So how…
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/20130430_Cryst_course.pdf2 May 2013: Acta Crystallogr. D Biol. Crystallogr. 60, 203–204 (2004). Solubility Screen. Protein characteriza0on 1-‐10mg/ml 100nl/drop Incubate 1-‐24 hrs. ... Or Jena Bioscience JBScreen Solubility HTS. Solubility Screen. Protein characteriza0on 1-‐10mg/ml -
pone.0052401 1..15
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Podosome2012/journal.pone.0052401.pdf10 Jan 2013: clear amphipathic characteristics and fold on membrane binding. [4]. A 24 and 28 amino acid long helix, H0, would be possible for. ... Members of the PAK family are major. effectors of the Rho GTPases CDC42 and Rac (reviewed in [24]). -
Kevin Cowtan, cowtan@ysbl.york.ac.uk 2012 Automated phase…
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/densitymod12-ppt.pdf28 May 2013: Slide 19. Slide 20. Slide 21. Slide 22. Slide 23. Slide 24. -
Slide 1
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/processing.pdf13 May 2013: approach. 24/44. 24/44. Integration by profile fitting. Based on the assumption that spots corresponding to fully recorded reflections in the same region of the detector (and on images nearby -
Expression, purifica0on, characteriza0on, and crystalliza0on So how…
https://www2.mrc-lmb.cam.ac.uk/download/03-protein-expression-crystallization-and-mutagenesis-meindert-lamers/?wpdmdl=18793&refresh=669d2bcc7ab2617215763962 May 2013: Acta Crystallogr. D Biol. Crystallogr. 60, 203–204 (2004). Solubility Screen. Protein characteriza0on 1-‐10mg/ml 100nl/drop Incubate 1-‐24 hrs. ... Or Jena Bioscience JBScreen Solubility HTS. Solubility Screen. Protein characteriza0on 1-‐10mg/ml -
Supplement_Final
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/81_Shao_S_Mol_Cell_2013.pdf16 May 2013: Molecular Cell. Article. Listerin-Dependent NascentProtein Ubiquitination Relieson Ribosome Subunit DissociationSichen Shao,1,2 Karina von der Malsburg,1,2 and Ramanujan S. Hegde1,1MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge -
Twinning and other pathologies Andrey Lebedev CCP4 OD-‐structures…
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/pathologies_and_twinning.pdf11 Jun 2013: 04/06/2013 Crystallography Course LMB 24. (Pseudo)merohedral twining is impossible. 432 622. ... Data processing ( -‐1 ). Molecular replacement ( P1 ). Refinement ( P1 ). R / R-‐free = 0.24 / 0.31. PDB: 1yup ( P1 ). PDB: 1yup. Zanuda. ( P21 ) -
Twinning and other pathologies Andrey Lebedev CCP4 OD-‐structures…
https://www2.mrc-lmb.cam.ac.uk/download/twinningaandaotherapathologiesa-andreyalebedeva-a/?wpdmdl=18788&refresh=669d2bcd0a584172157639711 Jun 2013: 04/06/2013 Crystallography Course LMB 24. (Pseudo)merohedral twining is impossible. 432 622. ... Data processing ( -‐1 ). Molecular replacement ( P1 ). Refinement ( P1 ). R / R-‐free = 0.24 / 0.31. PDB: 1yup ( P1 ). PDB: 1yup. Zanuda. ( P21 ) -
Kevin Cowtan, cowtan@ysbl.york.ac.uk 2012 Automated phase…
https://www2.mrc-lmb.cam.ac.uk/download/automated-phase-improvement-and-model-building-kevin-cowtan-cowtanysbl-york-ac-uk/?wpdmdl=18786&refresh=669d2bcd3e721172157639728 May 2013: Slide 19. Slide 20. Slide 21. Slide 22. Slide 23. Slide 24. -
Slide 1
https://www2.mrc-lmb.cam.ac.uk/download/integration-and-scaling-harry-powell-mrc-lmb-crystallography-course-10th-may-2013/?wpdmdl=18796&refresh=669d2bcc12794172157639613 May 2013: approach. 24/44. 24/44. Integration by profile fitting. Based on the assumption that spots corresponding to fully recorded reflections in the same region of the detector (and on images nearby -
Expression, purifica0on, characteriza0on, and crystalliza0on So how…
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/03-protein-expression-crystallization-and-mutagenesis-meindert-lamers/?wpdmdl=18793&2 May 2013: Acta Crystallogr. D Biol. Crystallogr. 60, 203–204 (2004). Solubility Screen. Protein characteriza0on 1-‐10mg/ml 100nl/drop Incubate 1-‐24 hrs. ... Or Jena Bioscience JBScreen Solubility HTS. Solubility Screen. Protein characteriza0on 1-‐10mg/ml -
MR_LMB
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/molecular-replacement/?wpdmdl=18799&11 Jun 2013: 24 (12) RF/TF. 3 (1) Pack. 3 (1) Refined. 307 (283) RF/TF. ... 68 (64) Pack. 24 (2) Refined. 32 (20) RF/TF. 22 (17) Pack. -
Kevin Cowtan, cowtan@ysbl.york.ac.uk 2012 Automated phase…
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/automated-phase-improvement-and-model-building-kevin-cowtan-cowtanysbl-york-ac-uk/?wpdmdl=18786&28 May 2013: Slide 19. Slide 20. Slide 21. Slide 22. Slide 23. Slide 24. -
Twinning and other pathologies Andrey Lebedev CCP4 OD-‐structures…
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/twinningaandaotherapathologiesa-andreyalebedeva-a/?wpdmdl=18788&11 Jun 2013: 04/06/2013 Crystallography Course LMB 24. (Pseudo)merohedral twining is impossible. 432 622. ... Data processing ( -‐1 ). Molecular replacement ( P1 ). Refinement ( P1 ). R / R-‐free = 0.24 / 0.31. PDB: 1yup ( P1 ). PDB: 1yup. Zanuda. ( P21 ) -
Slide 1
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/integration-and-scaling-harry-powell-mrc-lmb-crystallography-course-10th-may-2013/?wpdmdl=18796&13 May 2013: approach. 24/44. 24/44. Integration by profile fitting. Based on the assumption that spots corresponding to fully recorded reflections in the same region of the detector (and on images nearby
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