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  2. Understanding Infection Pathogenesis to Guide Therapies…

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_infection_pathogenesis_to_guide_therapies_non-technical_summary_redacted.pdf
    30 Apr 2024: Mice that are immunised can show mild signs of discomfort that should last no more than 24 hours.
  3. Pharmacological evaluation of imaging agents and development of…

    https://www.ubs.admin.cam.ac.uk/system/files/public/pharmacological_evaluation_of_imaging_agents_and_development_of_imaging_applications_and_methods_no_redacted.pdf
    30 Apr 2024: Production of the candidate imaging agent. PPL number: | Granted: 16 Feb 24 | Expires: 16 Feb 29. ... Mice. Non-recovery: 64%. Mild: 36%. Moderate: 0%. Severe: 0%. Rats. PPL number: | Granted: 16 Feb 24 | Expires: 16 Feb 29.
  4. Mechanisms controlling cell division and cell identity during…

    https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_controlling_cell_division_and_cell_identity_during_development_reprogramming_and_disease_redacted.pdf
    30 Apr 2024: These animals will be killed unless there are signs of recovery within 24 hours.
  5. Code of Practice for the Housing and Care of ...

    https://www.ubs.admin.cam.ac.uk/files/cop_housing_care_for_sci_purp.pdf
    18 Sep 2015: 5.1 Accommodation specifications 22. Section 1, Chapter 3: Rabbits 24 – 261 Accommodation specifications 24. ... 1.1 Doe plus litter 241.2 Breeding animals and post-weaned stock 241.3 Rabbits being used in procedures 24.
  6. Breeding and maintenance of rodents for drug discovery platform

    https://www.ubs.admin.cam.ac.uk/system/files/public/breeding_and_maintenance_of_rodents_for_drug_discovery_platform_non-technical_summary_redacted.pdf
    29 Apr 2024: Haem A, Haem B, and Glanzmann mice sometimes have surface bleeds that can be treated, and these usually resolve over 24 hours. ... Sometimes Haem A mice can have bleeds from the ears that also can, in most cases, resolve within 24 hours.
  7. PPL number: | Granted: 28 Oct 19 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_how_neutrophil_migration_behaviour_is_fine-tuned_during_inflammation_nts_redacted.pdf
    20 Aug 2021: PPL number: | Granted: 28 Oct 19 | Expires: 28 Oct 24.
  8. Cancer and its microenvironment! From mechanisms to translation…

    https://www.ubs.admin.cam.ac.uk/system/files/public/cancer_and_its_microenvironment_from_mechanisms_to_translation_non-technical_summary_redacted.pdf
    30 Apr 2024: PPL number: | Granted: 25 Jan 23 | Amended: 24 Jan 24 | Expires: 25 Jan 28. ... lung. PPL number: | Granted: 25 Jan 23 | Amended: 24 Jan 24 | Expires: 25 Jan 28.
  9. Biobehavioural basis of the individual vunerability to impulsive…

    https://www.ubs.admin.cam.ac.uk/system/files/public/biobehavioural_basis_of_the_individual_vulnerability_to_impulsivecompulsive_spectrum_disorders_redacted.pdf
    29 Apr 2024: PPL number: | Granted: 14 Jan 22 | Amended: 24 Jan 22 | Expires: 14 Jan 27. ... with. PPL number: | Granted: 14 Jan 22 | Amended: 24 Jan 22 | Expires: 14 Jan 27.
  10. Understanding the cell biology behind cardiovascular diseases…

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_the_cell_biology_behind_cardiovascular_diseases_non-technical_summary_redacted.pdf
    30 Apr 2024: subcutaneous 20ml/kg 2 24. Exceptions to this would be thioglycollate IP, which needs to be given in 1ml (standard practice), and the HDTV injection.
  11. PPL number: | Granted: 29 Jan 19 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/new_treatment_strategies_for_myocardial_infarction_and_aortic_aneurysm_nts_expires2024_redacted.pdf
    13 Sep 2021: PPL number: | Granted: 29 Jan 19 | Amended: 03 Sep 21 | Expires: 28 Jan 24. ... Contains severe proceduresRequired at inspector’s discretion. PPL number: | Granted: 29 Jan 19 | Amended: 03 Sep 21 | Expires: 28 Jan 24.
  12. Control of equine herpesviruses in the horse

    https://www.ubs.admin.cam.ac.uk/system/files/public/control_of_equine_herpesviruses_in_the_horse._non-technical_summary_redacted.pdf
    29 Apr 2024: PPL number: | Granted: 07 Apr 22 | Amended: 11 Mar 24 | Expires: 07 Apr 27. ... The PPL holder will be required to disclose:. PPL number: | Granted: 07 Apr 22 | Amended: 11 Mar 24 | Expires: 07 Apr 27.
  13. The development of in vivo expressed biologics as a platform for…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_development_of_in_vivo_expressed_biologics_as_a_platform_for_novel_therapeutic_agents_non-techn_redacted.pdf
    30 Apr 2024: PPL number: | Granted: 18 Apr 23 | Amended: 28 Mar 24 | Expires: 18 Apr 28. ... Reduction. PPL number: | Granted: 18 Apr 23 | Amended: 28 Mar 24 | Expires: 18 Apr 28.
  14. PPL number: | Granted: 20 Nov 19 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/neural_basis_of_spatial_cognition_and_memory_in_the_hippocampus_nts_redacted.pdf
    20 Aug 2021: All surgical. PPL number: | Granted: 20 Nov 19 | Expires: 20 Nov 24. ... Reduction. PPL number: | Granted: 20 Nov 19 | Expires: 20 Nov 24.
  15. Neurobehavioural Mechanisms Underlying Mood, Anxiety and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_underlying_mood_anxiety_and_stress-related_mental_health_disorders_non_redacted.pdf
    30 Apr 2024: We have published these findings in animal welfare journals. However, 24% of animals will need to experience more than three shocks, with the maximum number of footshocks that will be delivered ... Moderate: 76%. Severe: 24%. What will happen to animals
  16. Development of humanised mouse models for study of cancer…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_humanised_mouse_models_for_study_of_cancer_immunotherapy_non-technical_summary_redacted.pdf
    29 Apr 2024: In such cases, the animals will be culled if these clinical signs do not respond to treatment (such as high energy and easily digestible diet) and persist for up to 24
  17. Generation and screening of companion animal therapeutics.…

    https://www.ubs.admin.cam.ac.uk/system/files/public/generation_and_screening_of_companion_animal_therapeutics._non-technical_summary_redacted.pdf
    30 Apr 2024: Companion animal immunoglobulin. PPL number: | Granted: 10 Apr 24 | Expires: 10 Apr 29. ... Substances will be. PPL number: | Granted: 10 Apr 24 | Expires: 10 Apr 29.
  18. Provision of an outsourced drug discovery platform for the…

    https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_the_development_of_therapeutic_drugs_for_neur_redacted.pdf
    30 Apr 2024: This allows unsuitable drugs to be. PPL number: | Granted: 24 Mar 22 | Expires: 24 Mar 27. ... Blood samples are usually small in volume and are. PPL number: | Granted: 24 Mar 22 | Expires: 24 Mar 27.
  19. The development of novel therapies (including cell and gene based…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_development_of_novel_therapies_including_cell_and_gene_based_approaches_for_parkinsons_and_hu_redacted.pdf
    30 Apr 2024: PPL number: | Granted: 21 Mar 24 | Expires: 21 Mar 29. ... Over the period 24-96h, animals may show reduced appetite for food and water, which is expected to result in minor weight loss (less than 5-10% of their pre-operative
  20. PPL number: | Granted: 16 Apr 19 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_of_mental_health_nts_expires2023_redacted.pdf
    13 Sep 2021: If no improvement was shown within 24 hours, then the animal would be humanely killed.
  21. Ischaemia Reperfusion Injury and Organ Transplantation (non-technical …

    https://www.ubs.admin.cam.ac.uk/system/files/public/ischaemia_reperfusion_injury_and_organ_transplantation_non-technical_summary_redacted.pdf
    30 Apr 2024: PPL number: | Granted: 03 Jul 23 | Expires: 03 Jul 28. Downloaded: 9:27pm, 25 Apr 2024 Page 2 of 11. Objectives and benefitsDescription of the projects objectives, for example the scientific unknowns or clinical orscientific needs it's addressing.

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