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Protein-driven membrane stresses in fusion and fission
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Kozlov%20Trends%20Biochem%20Sci%202010.pdf20 Nov 2010: Frequent observations of a complex network ofconnected tubules with an extensive surface area implythat considerable EHD2-driven fusion occurs betweentubulated liposomes [24]. ... 2009) The BAR domain superfamily: membrane-molding macromolecules. Cell 137 -
Roles of Amphipathic Helices and the Bin/Amphiphysin/Rvs(BAR) Domain…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Jao_JBC2010.pdf4 Oct 2010: Distances 20Å were investigated using four-pulse DEER (24–27), whereasshorter distances were investigated using continuous wave EPR(28, 29) (see “Experimental Procedures”).The DEER measurements are illustrated with the example ... Mutant -
Features critical for membrane binding revealed by DivIVA crystal…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/emboj201099a.pdf20 May 2010: 21.7) 24.1 (ano. 14.1) 3.8 4.3 (ano. 2.5) 2.8. Phasing Se SAD Ta SAD MR I SAD MRNumber of sites 6 5 8Mean FOM -
Crystal Structures of Bacillus subtilis Lon Protease
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/londumanjmb2010.pdf20 Jul 2010: electron microscopy data show that negativelystained images of E. coli Lon particles appearhexameric,24 although surprisingly, electron cryo-microscopy images of S. -
©20 10 N atur e A mer ica, Inc. ...
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/20081827.pdf2 Aug 2010: Impaired PI(3)K signaling results in severe defects of innate and adaptive immune responses, suggesting that targeting of this isoform would be a beneficial therapeutic strategy20,24. ... Biochem. Soc. Trans. 35, 245–249 (2007). 24. Ameriks, M.K. & -
bst641-09a
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/19614567.pdf2 Aug 2010: In contrast with the class IA enzymes, the single class IBisotype, p110γ , associates with p101 [23] or the closely relatedp84–p87 regulatory subunits [24,25]; neither subunit has arecognizable domain organization ... The p84–p110γ heterodimer is -
The Acetyltransferase Activity of the Bacterial Toxin YopJ ofYersinia …
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Mittal_JBC2010.pdf4 Oct 2010: The Acetyltransferase Activity of the Bacterial Toxin YopJ ofYersinia Is Activated by Eukaryotic Host Cell InositolHexakisphosphateSReceived for publication, March 24, 2010, and in revised form, April 23, 2010 Published, JBC Papers ... They are also the -
Modeling membrane shaping by proteins: Focus on EHD2 and N-BAR domains
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/KozlovEHDs.pdf7 Apr 2010: 18–20]), the BAR domain con-taining proteins [14,21–24], EHD2 [25], the complexes of clathrinwith adaptor and accessory proteins (see for reviews e.g. -
A positively charged channel within the Smc1/Smc3 hinge required for…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/embosmcjingekurze2010.pdf1 Dec 2010: Smc1DDSmc3AAA. Smc1Smc3AAA. Kd = 22 nM Kd = 29 nM Kd = 24 nM. ... The Kd for Smc1DD and Smc3AAA hingedomain association is 29 nM (middle panel) and 24 nM for Smc1 wild-type and Smc3AAA (right panel). -
JFCregg_OGS_finaledit
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/Cregg_thesis.pdf14 Dec 2010: Egg-laying. 17. Neurophysiology in C. elegans. 24. Electrophysiology. 25. vi. Calcium Imaging. ... receptors. The worms will eventually (in 12 – 24 hrs) adapt to high levels of.
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