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A cellular pacemaker in the central body clock - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/a-cellular-pacemaker-in-the-central-body-clock/7 Jul 2020: Our behaviour, and the functions of our cells, follow a daily cycle in line with the 24-hour day. -
Balancing an appropriate immune response in the gut - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/balancing-an-appropriate-immune-response-in-the-gut/8 Jul 2020: Menna Clatworthy’s group has identified a key signalling molecule in determining the balance between wound healing and defence against bacterial invasion, with implications for our understanding of the immune system’s role in inflammatory bowel -
The LMB welcomes Ana Tufegdzic Vidakovic as a new Group Leader - MRC…
https://www2.mrc-lmb.cam.ac.uk/the-lmb-welcomes-ana-tufegdzic-vidakovic-as-a-new-group-leader/15 Jul 2020: Ana Tufegdzic Vidakovic joins as a new Group Leader in the PNAC Division, where she will continue her work on regulation of transcription in the context of DNA damage. -
Atomic advance for cryo-EM - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/atomic-advance-for-cryo-em/21 Oct 2020: Apoferritin is commonly used as a benchmark for cryo-EM, because its molecular stability and 24-fold symmetry allow high-resolution reconstructions from relatively few particles. -
A simple, novel mechanism to safeguard the integrity of the human…
https://www2.mrc-lmb.cam.ac.uk/a-simple-novel-mechanism-to-safeguard-the-integrity-of-the-human-genome/21 Aug 2020: Nearly half of the human genome is composed of various forms of DNA repeat. Pierre Murat in Julian Sale’s group has revealed a mechanism that safeguards the genome from pathological expansion of one group of DNA repeats known as STRs. -
Scientific collaboration to focus on search for new, improved…
https://www2.mrc-lmb.cam.ac.uk/scientific-collaboration-to-focus-on-search-for-new-improved-detectors-for-low-energy-cryo-em/11 Mar 2020: New multi-million-pound initiative between The Rosalind Franklin Institute and the LMB aims to develop a new detector to produce better data and make cryo-EM more accessible. -
First complete atomic model of condensin lays foundation for…
https://www2.mrc-lmb.cam.ac.uk/first-complete-atomic-model-of-condensin-lays-foundation-for-understanding-chromosome-compaction/14 Jul 2020: Each of our cells contains about two metres of DNA. To be able to store all of this, the DNA must be very tightly compacted. Jan Löwe’s group have produced the first atomic model of condensin, a complex known to have a role in compacting DNA into -
César Milstein Lecture to be given by Elaine Fuchs - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/cesar-milstein-lecture-to-be-given-by-elaine-fuchs/21 Jan 2020: He died in Cambridge on 24 March 2002. Further references:. Primary Sidebar. -
Publications
https://www2.mrc-lmb.cam.ac.uk/groups/jes/publications.html17 Sep 2020: Histone H3.3 is required to maintain replication fork progression after UV damage Current Biology 24, 2195-201. -
Science Magazine dives into the science behind affordable cryo-EM -…
https://www2.mrc-lmb.cam.ac.uk/science-magazine-dives-into-the-science-behind-affordable-cryo-em/24 Jan 2020: 24 January, 2020. In long feature format, Science Magazine profiles structural biology scientists at the LMB, including Chris Russo and Nobel Prize winner Richard Henderson, and their work on bringing
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