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Kinetic modelling indicates that fast-translating codons can…
www-vendruscolo.ch.cam.ac.uk/obrien2014nc.pdf8 Jan 2014: þXij1. kIU;jkUF;jDj. Yiljþ1. kA;l þ1kA;l þ1 þkIU;l þkUI;l þkUF;lDl. :. ð6Þ. ... determine the derivative in terms of kA,iþ1; weprovide the exact expression in Supplementary Eq. -
Cooperative Assembly of Hsp70 Subdomain Clusters
www-vendruscolo.ch.cam.ac.uk/wright2018b.pdf23 Sep 2018: 3 = ka/k, we could determine the elongation rateconstant to be approximately ⟨k+⟩ = 2.0 1.2 M. ... For the two-state fits, the imposed bounds were ka 0, K̃ 1, and 0 α 1 1018. -
ar5000117 1..9
www-vendruscolo.ch.cam.ac.uk/obrien2014acr.pdf2 Jun 2014: The rate kA,i1 isan important quantity because it defines the average speed atwhich codon i is translated.The other relevant rates are those associated with the process. ... and genomic sequences. This information enables reasonableestimates of kA,i1, kFU -
ja407951x 1..10
www-vendruscolo.ch.cam.ac.uk/biedermann2013jacs.pdf4 Oct 2013: 14,15 Besides, the higher affinity of Phe-(Gly)2(Ka,ternary = 2 10. ... contribution for hostguest binding (Ka up to 106M1, ΔH up to 70 kJ mol1). -
The Amyloid-β Pathway in Alzheimer’s Disease
www-vendruscolo.ch.cam.ac.uk/Hampel-2021-Molecular-Psychiatry.pdf28 Sep 2021: REVIEW ARTICLE OPEN. The Amyloid-β Pathway in Alzheimer’s DiseaseHarald Hampel 1, John Hardy2, Kaj Blennow3,4, Christopher Chen 5, George Perry 6, Seung Hyun Kim7,Victor L. Villemagne 8,9, Paul Aisen10, Michele Vendruscolo 11, Takeshi Iwatsubo12, -
Exploring the role of post‐translational modifications in regulating…
www-vendruscolo.ch.cam.ac.uk/elturk2018ps.pdf23 Sep 2018: Na DHbb (kcal/mol) –TDSb. c (kcal/mol) DGbd (kcal/mol) Ka (10. 7 M21)e Kd (1029 M)e. ... kona (106 M21 s21) koff. a (1023 s21) Ka (107 M21)b Kd (10. -
The codon information index: a quantitative measure of the…
www-vendruscolo.ch.cam.ac.uk/caniparoli2013jsm.pdf16 Jul 2013: where Ka is the number of codons encoding for the amino acid a, ns,a(ca) is the number of. ... times a spin s is associated to the codon ca of the amino acid a and Ns,a =Ka. -
pcbi.1002169 1..9
www-vendruscolo.ch.cam.ac.uk/fitzpatrick11pcb.pdf15 Jan 2012: Dill KA (1985) Theory for the folding and stability of globular proteins. -
JCB: Article The Rockefeller University Press $30.00J. Cell Biol. ...
www-vendruscolo.ch.cam.ac.uk/chambers12jcb.pdf14 Aug 2012: ka Aggregation of U 5 m3(n1)mol(n1)min1. n Power dependence of aggregation. ... Thus, we speculate. Table 2. Correlating changes in the parameters kf, ka, and n with outputs in the ADPr and ADPr+ models. -
pone.0072286 1..5
www-vendruscolo.ch.cam.ac.uk/waudby2013po.pdf4 Oct 2013: doi:10.1074/jbc.M109541200. 4. Weinreb PH, Zhen W, Poon AW, Conway KA, Lansbury PT (1996) NACP, a.
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