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29 Apr 2024: Jan Löwe's group at the MRC Laboratory of Molecular Biology. Jan Löwe's ORCID identifier: 0000-0002-5218-6615. For statistics such as h-index and citation numbers please consult Google Scholar: Jan Löwe's profile. 2024. Hale V., Hooker J., Russo C

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AA, Kaufman TC, Knoblich J, Malik HS, Matthews KA, O’Connor-Giles KM, Parks AL, Perrimon N, Port F, Russell S, Ueda R, Wildonger J (2015) Biosafety: Safeguarding gene drive experiments

MM, Hayes KR, James AA, Kaufman TC, Knoblich J, Malik HS, Matthews KA, O’Connor-Giles KM, Parks AL, Perrimon N, Port F, Russell S, Ueda R, Wildonger J (2015) Biosafety:

{"id":18964,"date":"2020-08-18T14:05:27","date_gmt":"2020-08-18T13:05:27","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=18964"},"modified":"2022-03-21T15:56:30","modified_gmt":"2022-03-21T15:56:30","slug":"studying-the-spike-protein-of-sars-c

15 Sep 2020: For correspondence:. jyl@mrc-lmb.cam.ac.uk (JL);. ashley.nasmyth@bioch.ox.ac.uk. (KAN). †These authors contributed. equally to this work. Competing interests: The. authors declare that no. competing interests exist. Funding: See page 33. Received:

18 Aug 2020: Xiong, X., Qu, K., Ciazynska, KA., Hosmillo, M., Carter, AP., Ebrahimi, S., Ke, Z., Scheres, SHW., Bergamaschi, L., Grice, GL., Zhang, Y., The CITIID-NIHR COVID-19 BioResource Collaboration, Nathan, JA.,

KG, Gratz SJ, Harrison MM, Hayes KR, James AA, Kaufman TC, Knoblich J, Malik HS, Matthews KA, O’Connor-Giles KM, Parks AL, Perrimon N, Port F, Russell S, Ueda R,

6 Feb 2008: Affinities were calculated via fitting titration curves to the data. This resulted in the stoichiometry N, the binary equilibrium constant Ka, the dissociation constant Kd (which equals 1/Ka), the enthalpy

1 Jul 2011: Int JBiochem Cell Biol 41:323–329[3] Aylett CH, Wang Q, Michie KA et al. ... Cell 115:705–713[12] Michie KA, Löwe J (2006) Dynamic filaments of the bac-terial cytoskeleton.

28 Nov 2023: McMullan, G., Naydenova, K., Mihaylov, D., Yamashita, K., Peet, MJ., Wilson, H., Dickerson, JL., Chen, S., Cannone, G., Lee, Y., Hutchings, KA., Gittins, O., Sobhy, MA., Wells, T., El-Gomati, MM.,

KR, Duchek P, Edwards OR, Esvelt K, Gantz VM, Golic KG, Gratz SJ, Harrison MM, Hayes KR, James AA, Kaufman TC, Knoblich J, Malik HS, Matthews KA, O’Connor-Giles KM,

16 Jul 2003: smaller ka) but prolonged its membrane residence by3-fold (i.e. smaller kd). ... Proteins ka kd kdFold increase. in Kda. M 1 s 1 s 1 M.

11 Aug 2015: 2168 | K. von der Malsburg et al. Molecular Biology of the Cell. MBoC | ARTICLE. The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 transloconKarina von der Malsburg, Sichen Shao, and Ramanujan S. HegdeMRC

3 Jul 2024: A thermostable, closed SARS-CoV-2 spike protein trimer./a Xiong, X., Qu, K., Ciazynska, KA., Hosmillo, M., Carter, AP., Ebrahimi, S., Ke, Z., Scheres, SHW., Bergamaschi, L., Grice, GL., Zhang,

12 Oct 2002: The enhanced membrane afnity of the p47phox-PXdomain due to 3 mol% PtdIns(3,4)P2 is almost entirely dueto a decrease in the kd, with the ka remaining nearlyconstant. ... Phosphoinositide ka (M1 s1) kd (s. 1) Kd (M) Fold increase in Kda.

11 Nov 2010: Nature 413:39–44. 3. Aylett CHS, Wang Q, Michie KA, Amos LA, Löwe J(2010) Filament structure of bacterial tubulin homo-logue TubZ.

4 Dec 2007: Also recall that: KD = k-1 / k1 = [P]free [L]free/ [PL] = 1 / KA. ... y = [PL] / ([P]free+ [PL]) • Use [PL] = KA [P]free [L]free. •

25 Nov 2012: Full lipid-binding curves used tocalculate Ka values are in Fig. S7. ... B) Protein–lipid FRET assays were per-formed with 5% PIP2 vesicles, and Ka was calculated for both 5 μM pY.

19 Apr 2002: tide linker had little or no effect on its ability to bindstate affinity measurements to estimate on rate (ka), offrate (kd), and affinity (KA ka/kd) constants by measuring Scc1 (Figure ... dissociation rate constants (ka and kd, respectively) are