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  2. Robotic crystallisation: LMB plates

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/WWWrobots/robot-nomenclature.html
    27 Sep 2022: PEG-Ion. Hampton Research. HR2-126. 48. Grid screen, conc. PEG 3350 = 20% w/v and various salts at 0.2 M (no buffers).
  3. In-person public engagement returns after lockdown - MRC Laboratory…

    https://www2.mrc-lmb.cam.ac.uk/in-person-public-engagement-returns-after-lockdown/
    Thumbnail for In-person public engagement returns after lockdown - MRC Laboratory of Molecular Biology 13 Apr 2022: In-person public engagement is returning after a long hiatus during the pandemic. LMB scientists took part in British Science Week with schools and at the Cambridge Festival.
  4. John Jarvis (1942 – 2022) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/john-jarvis-1942-2022/
    Thumbnail for John Jarvis (1942 – 2022) - MRC Laboratory of Molecular Biology 20 Sep 2022: Published on. 20 September, 2022. John Jarvis. John Jarvis, a former research assistant, who spent nearly 40 years at the LMB working alongside César Milstein, in the PNAC Division, died on
  5. Donald Caspar 1927 – 2021 - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/donald-caspar-1927-2021/
    Thumbnail for Donald Caspar 1927 – 2021 - MRC Laboratory of Molecular Biology 7 Jan 2022: He would become a frequent scientific worker at the Lab over the next 20 years and remained a friend and scientific colleague to many. ... Exploring implications of the icosahedral virus symmetry he had discovered kept him returning to the LMB for the
  6. Curios of 60 years of the LMB - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/curios-of-60-years-of-the-lmb/
    Thumbnail for Curios of 60 years of the LMB - MRC Laboratory of Molecular Biology 30 Mar 2022: The models, made over 30 years apart, are remarkably similar in overall shape, but with the earlier one representing a 20 Ångstrom (low-resolution) structure and the later 2 Ångstrom
  7. Aaron Klug: A Scientific Retrospective - MRC Laboratory of Molecular…

    https://www2.mrc-lmb.cam.ac.uk/aaron-klug-a-scientific-retrospective/
    Thumbnail for Aaron Klug: A Scientific Retrospective - MRC Laboratory of Molecular Biology 7 Jun 2022: honour. Aaron, Nobel Laureate, former Director of the LMB and former President of The Royal Society, died on 20. ... Tony Crowther: Sir Aaron Klug OM. 11 August 1926 – 20 November 2018.
  8. Fred Sanger (1918 - 2013) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/fred-sanger/
    Thumbnail for Fred Sanger (1918 - 2013) - MRC Laboratory of Molecular Biology 6 Oct 2022: This method would shape the way that genomics and biomedicine were explored and was key to the Human Genome Project, the international collaboration to identify all the approximately
  9. Fred Sanger at the LMB - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-news/fred-sanger-at-the-lmb-2/
    Thumbnail for Fred Sanger at the LMB - MRC Laboratory of Molecular Biology 6 Oct 2022: With the techniques available at the time a sequence with only four elements was much more difficult to solve than a sequence with 20 elements.
  10. Constructive Bio launched to build on synthetic biology breakthroughs …

    https://www2.mrc-lmb.cam.ac.uk/constructive-bio-launched-to-build-on-synthetic-biology-breakthroughs/
    Thumbnail for Constructive Bio launched to build on synthetic biology breakthroughs - MRC Laboratory of Molecular Biology 19 Aug 2022: Jason commented, “Over the last 20 years, we have created a cellular factory that we can reliably and predictably program to create new polymers.
  11. Pi-PEG Screen 1.5 disclaimer

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB19.pdf
    28 Sep 2022: MME 8.55 % 1-19 PEG 300 25.65 % HEPES 75 mM 7.1 PEG 600 8.55 % 1-20 PEG 350 MME 25.65 % HEPES 75 mM 7.3 PEG ... 15 % 2-19 PEG 600 8.55 % HEPES 75 mM 7.1 PEG 300 42.9 % 2-20 PEG 1000 7.5 % HEPES 75 mM 7.3 PEG 350 MME
  12. Cryptochrome proteins are integral to maintain time within the…

    https://www2.mrc-lmb.cam.ac.uk/cryptochrome-proteins-are-integral-to-maintain-time-within-the-brains-master-clock/
    Thumbnail for Cryptochrome proteins are integral to maintain time within the brain’s master clock - MRC Laboratory of Molecular Biology 20 Jan 2022: Published on. 20 January, 2022. A schematic showing the effect of CRY1 on the relationships between localisation and intracellular mobility of endogenous fluorescently tagged PER2 as well as circadian rhythmicity of ... This circadian rhythm is
  13. Mammalian clock gene Cryptochrome 1 is crucial to suprachiasmatic…

    https://www2.mrc-lmb.cam.ac.uk/mammalian-clock-gene-cryptochrome-1-is-crucial-to-suprachiasmatic-nucleus-timekeeping/
    Thumbnail for Mammalian clock gene Cryptochrome 1 is crucial to suprachiasmatic nucleus timekeeping - MRC Laboratory of Molecular Biology 31 Aug 2022: Circadian rhythms, which dominate our daily lives and are implicated in many health disorders, are governed by the suprachiasmatic nucleus (SCN) – a network of approximately 20,000 cells in the hypothalamus
  14. Identical structures of α-synuclein filaments from Parkinson’s…

    https://www2.mrc-lmb.cam.ac.uk/identical-structures-of-%CE%B1-synuclein-filaments-from-parkinsons-disease-and-dementia-with-lewy-bodies/
    Thumbnail for Identical structures of α-synuclein filaments from Parkinson’s disease and dementia with Lewy bodies - MRC Laboratory of Molecular Biology 20 Sep 2022: Published on. 20 September, 2022. Cryo-EM reveals both neurodegenerative diseases possess identical Lewy fold structure.
  15. Clinical study reveals striking daily temperature variation in the…

    https://www2.mrc-lmb.cam.ac.uk/clinical-study-reveals-striking-daily-temperature-variation-in-the-human-brain-that-predicts-survival-after-brain-injury/
    Thumbnail for Clinical study reveals striking daily temperature variation in the human brain that predicts survival after brain injury - MRC Laboratory of Molecular Biology 13 Jun 2022: To compare these data with healthy brains, the researchers recruited 40 healthy volunteers (20 males, 20 females, aged 20-40 years) for non-invasive brain thermometry. ... This finding was quite unexpected given the confined age range (20-40 years) of
  16. Integrin-mediated T helper 2 cell clustering revealed as key step and …

    https://www2.mrc-lmb.cam.ac.uk/integrin-mediated-t-helper-2-cell-clustering-revealed-as-key-step-and-potential-therapeutic-target-in-allergic-immune-response/
    Thumbnail for Integrin-mediated T helper 2 cell clustering revealed as key step and potential therapeutic target in allergic immune response - MRC Laboratory of Molecular Biology 22 Dec 2022: Allergy and allergic asthma result from inappropriate immune reactions. According to the charity Allergy UK, allergic diseases affect 20% of the UK and world population. ... in the mouse genome (20,000) for their involvement in IL-13 production.
  17. Collaborative LMB study reveals S-shaped structure of Aβ42 filaments…

    https://www2.mrc-lmb.cam.ac.uk/collaborative-lmb-study-reveals-s-shaped-structure-of-a%CE%B242-filaments-in-alzheimers-disease-and-other-neurodegenerative-diseases/
    Thumbnail for Collaborative LMB study reveals S-shaped structure of Aβ42 filaments in Alzheimer’s disease and other neurodegenerative diseases - MRC Laboratory of Molecular Biology 20 Jan 2022: Published on. 20 January, 2022. A recent structural study led by Sjors Scheres, Michel Goedert and Benjamin Ryskeldi-Falcon’s groups at the LMB has used cryo-EM to detect two
  18. Coot Tutorial CCP4 Summer School 2021 October 19, 2022 ...

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/tutorial/tutorial.pdf
    19 Oct 2022: 20. Coot’s Go To Atom Window (it doesn’t look exactly like this any more). •
  19. Donald Caspar (1927 – 2021) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/donald-caspar-1927-2021/
    Thumbnail for Donald Caspar (1927 – 2021) - MRC Laboratory of Molecular Biology 5 Jan 2022: He would become a frequent scientific worker at the Lab over the next 20 years and remained a friend and scientific colleague to many. ... Exploring implications of the icosahedral virus symmetry I had discovered kept me returning to the MRC Lab for the
  20. Structure of a cholinergic cell membraneNigel Unwina,1 Edited by ...

    https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/pnasS22.pdf
    4 Nov 2022: struction, using local averaging to combine the three-dimensional data from multiplesubsets (17, 20). ... IUCrJ 4,393–399 (2017). 20. A. Miyazawa, Y. Fujiyoshi, M. Stowell, N.
  21. PNAS202120006_proof

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/pnas%20Lee%202022.pdf
    18 Dec 2022: S2A). ABC-typeATPases bound to ADP.BeF3 often represent the enzyme–substrate complex (20). ... The peak fractionswere concentrated using a Vivaspin 20 100,000-Da centrifugal concentrator andfrozen.

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