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High-resolution structure of a GPCR-arrestin complex - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/first-high-resolution-structure-of-a-gpcr-arrestin-complex/17 Jun 2020: Understanding minute structural differences in (G protein-coupled receptor) GPCR complexes could lead to the design of more efficacious drugs that have fewer side effects -
Scientific collaboration to focus on search for new, improved…
https://www2.mrc-lmb.cam.ac.uk/scientific-collaboration-to-focus-on-search-for-new-improved-detectors-for-low-energy-cryo-em/11 Mar 2020: New multi-million-pound initiative between The Rosalind Franklin Institute and the LMB aims to develop a new detector to produce better data and make cryo-EM more accessible. -
Max Perutz Lecture to be given by John Diffley - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/max-perutz-lecture-to-be-given-by-john-diffley/20 Feb 2020: 20 February, 2020. Francis Crick Institute. ‘How our chromosomes are replicated’ is the title of the 2019 Max Perutz Lecture to be given by John Diffley on Wednesday 26th February at -
Daffodils announce LMB staff's fundraising for Marie Curie - MRC…
https://www2.mrc-lmb.cam.ac.uk/daffodils-announce-lmb-staffs-fundraising-for-marie-curie/23 Mar 2020: And this month, during the Great Daffodil Appeal by Marie Curie, Freda collected another £155.05, bring the total to £695.20. -
TRIM21 links antibody and T cell immunity to combat viral infection - …
https://www2.mrc-lmb.cam.ac.uk/trim21-links-antibody-and-t-cell-immunity-to-combat-viral-infection/4 Dec 2020: Our immune system generates a strong antibody response against nucleoproteins, but the role of this has not been understood. Leo James’ group has revealed a new mechanism that could have important implications for SARS-CoV-2 vaccination and -
A connection between stress detection and lifestyle decisions in…
https://www2.mrc-lmb.cam.ac.uk/a-connection-between-stress-detection-and-lifestyle-decisions-in-worms/24 Nov 2020: Rebecca Taylor’s group has identified a signalling molecule that connects detection of a stressful environment by the nervous system with molecular defence mechanisms in other tissues and leads to changes in feeding behaviour and reproduction. -
Coot Cryo-EM Tutorial 2: Fitting and Mutating | Coot Development Blog
https://www2.mrc-lmb.cam.ac.uk/coot/blog/2020/10/20/Coot-Cryo-EM-main.html20 Oct 2020: Coot Cryo-EM Tutorial 2: Fitting and Mutating. Oct 20, 2020. By Ana Casañal & Paul Emsley. ... Close. You should now have an extra map (“emd_3908.map Blur 20.00”). -
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/pdb6f9n.ent
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/pdb6f9n.ent9 Nov 2020: 2961 REMARK 3 19 2.9639 - 2.9110 0.99 4236 208 0.2988 0.3733 REMARK 3 20 2.9110 - 2.8616 1.00 4096 199 0.3121 0.3584 ... ASP A 100 -130.21 60.86 REMARK 500 TYR A 155 14.27 59.23 REMARK 500 THR A 157 -33.20 -134.12 REMARK 500 ARG A 194 -
A novel tau fold in the neurodegenerative disease corticobasal…
https://www2.mrc-lmb.cam.ac.uk/a-novel-tau-fold-in-the-neurodegenerative-disease-corticobasal-degeneration/13 Feb 2020: 3R). There are more than 20 different tauopathies, with Alzheimer’s disease being the most common. -
From metastasis to your favourite biscuit: connecting with school…
https://www2.mrc-lmb.cam.ac.uk/from-metastasis-to-your-favourite-biscuit-connecting-with-school-students-from-home/12 Aug 2020: For 12 weeks from late April, more than 20 LMB scientists have been taking part in the Medical Research Zone of the online public engagement platform I’m a Scientist, Stay
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