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TRIM21 links antibody and T cell immunity to combat viral infection - …
https://www2.mrc-lmb.cam.ac.uk/trim21-links-antibody-and-t-cell-immunity-to-combat-viral-infection/4 Dec 2020: Our immune system generates a strong antibody response against nucleoproteins, but the role of this has not been understood. Leo James’ group has revealed a new mechanism that could have important implications for SARS-CoV-2 vaccination and -
A connection between stress detection and lifestyle decisions in…
https://www2.mrc-lmb.cam.ac.uk/a-connection-between-stress-detection-and-lifestyle-decisions-in-worms/24 Nov 2020: Rebecca Taylor’s group has identified a signalling molecule that connects detection of a stressful environment by the nervous system with molecular defence mechanisms in other tissues and leads to changes in feeding behaviour and reproduction. -
Coot Cryo-EM Tutorial 2: Fitting and Mutating | Coot Development Blog
https://www2.mrc-lmb.cam.ac.uk/coot/blog/2020/10/20/Coot-Cryo-EM-main.html20 Oct 2020: Coot Cryo-EM Tutorial 2: Fitting and Mutating. Oct 20, 2020. By Ana Casañal & Paul Emsley. ... Close. You should now have an extra map (“emd_3908.map Blur 20.00”). -
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/pdb6f9n.ent
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/pdb6f9n.ent9 Nov 2020: 2961 REMARK 3 19 2.9639 - 2.9110 0.99 4236 208 0.2988 0.3733 REMARK 3 20 2.9110 - 2.8616 1.00 4096 199 0.3121 0.3584 ... ASP A 100 -130.21 60.86 REMARK 500 TYR A 155 14.27 59.23 REMARK 500 THR A 157 -33.20 -134.12 REMARK 500 ARG A 194 -
A novel tau fold in the neurodegenerative disease corticobasal…
https://www2.mrc-lmb.cam.ac.uk/a-novel-tau-fold-in-the-neurodegenerative-disease-corticobasal-degeneration/13 Feb 2020: 3R). There are more than 20 different tauopathies, with Alzheimer’s disease being the most common. -
From metastasis to your favourite biscuit: connecting with school…
https://www2.mrc-lmb.cam.ac.uk/from-metastasis-to-your-favourite-biscuit-connecting-with-school-students-from-home/12 Aug 2020: For 12 weeks from late April, more than 20 LMB scientists have been taking part in the Medical Research Zone of the online public engagement platform I’m a Scientist, Stay -
Cell-invading bacteria are converted into signalling platforms that…
https://www2.mrc-lmb.cam.ac.uk/cell-invading-bacteria-are-converted-into-signalling-platforms-that-may-trigger-septic-shock/15 Jun 2020: Septic shock is a common cause of death that can be triggered by LPS, a component of the outer membrane of some bacteria. Felix Randow’s group has shown how the immune response against cytosol-invading bacteria is activated by a signalling -
A new layer of complexity in GPCR signalling could explain…
https://www2.mrc-lmb.cam.ac.uk/a-new-layer-of-complexity-in-gpcr-signalling-could-explain-differences-in-receptor-function-and-drug-response/5 Nov 2020: GPCRs are the target of approximately 34% of approved drugs, reflecting their key role in cell function. Madan Babu’s group has uncovered how different receptor isoforms, existing in different combinations, could generate tissue-specific responses -
Impress
https://www2.mrc-lmb.cam.ac.uk/coot/ephemera/beyond-coloured-lines.pdf28 Sep 2020: detailed, interactive representation of “high energy”. 20 / 50. Colour-blindness Considerations. ... Slide 18. Slide 19. Slide 20. Slide 21. Slide 22. Slide 23. -
MD1-116-117 Morpheus III-Morpheus III HT-96
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/WWWrobots/LMB%20plates/LMB22.pdf13 Oct 2020: Catalogue Number (250 mL). 60% Precipitant Mix 1 40% v/v PEG 500 MME; 20 % w/v PEG 20000. ... MD2-100-82 MD2-250-82. 60% Precipitant Mix 3 40% v/v Glycerol; 20% w/v PEG 4000.
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