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F. J. Leeper Group Homepage
www-leeper.ch.cam.ac.uk/Abs033.html25 Oct 2013: lsobacteriochlorins carrying a C-methyl group at C-20 of the macrocycle are important for research on the biosynthesis of vitamin B. ... 12. Several different approaches are studied which allow the introduction of a C-20 methyl group into model -
F. J. Leeper Group Homepage
www-leeper.ch.cam.ac.uk/Abs039.html25 Oct 2013: 12. Biosynthesis: The Glutamate Route to (-)-Ring-B Imide and Synthesis of the 2,7,12,20-Tetramethylisobacteriochlorin". ... An enantioselective synthesis of (-)-ring-B imide (19) from inexpensive glutamic acid is described and the product is used for -
F. J. Leeper Group Homepage
www-leeper.ch.cam.ac.uk/Abs038.html25 Oct 2013: R. Battersby. "Syntheses Relevant to Vitamin B. 12. Biosynthesis: The Malate Route to (-)-Ring-B Imide and Synthesis of the 2,7,20-Trimethylisobacteriochlorin". ... An efficient enantioselective synthesis of (-)-ring-B imide (19) from R-malic acid is -
F. J. Leeper Group Homepage
www-leeper.ch.cam.ac.uk/Abs113.html25 Oct 2013: mobilis, with K. I. values down to 20 pM; this system was used to explore pyrophosphate mimics and several effective analogues were discovered. -
F. J. Leeper Group Homepage
www-leeper.ch.cam.ac.uk/Abs010.html25 Oct 2013: Heterocycles,1983, 20, 65-68. -
F. J. Leeper Group Homepage
www-leeper.ch.cam.ac.uk/Abs044.html25 Oct 2013: Incorporation of 11S-[11-. 2. H]- and 11R-[11-. 2. H]-Porphobilinogen into Sirohydrochlorin and 2,7,20-Trimethylisobacteriochlorin". -
F. J. Leeper Group Homepage
www-leeper.ch.cam.ac.uk/Abs020.html25 Oct 2013: Abstract. 20. M. H. Block, S. C. Zimmerman, G. B. Henderson, S. -
F. J. Leeper Group Homepage
www-leeper.ch.cam.ac.uk/Abs066.html25 Oct 2013: 1,10,20-. 13. C. 3. ]Uro'gen III is unambiguously synthesised for enzymic conversion into precorrin-4 isolated after aerial oxidation as two epimers of Factor IV, the. -
F. J. Leeper Group Homepage
www-leeper.ch.cam.ac.uk/Abs120.html25 Oct 2013: Pyrophosphorylation then gave extremely potent triazole inhibitors with K. I. values down to 20 pM, compared to a K. -
F. J. Leeper Group Homepage
www-leeper.ch.cam.ac.uk/Abs024.html25 Oct 2013: Earlier work had established that the first 3 methyl groups are introduced at positions 2,7, and 20 in that order.
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