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https://www2.mrc-lmb.cam.ac.uk/groups/jes/publications.html17 Sep 2020: and Sale, J.E.† (2014). Determinants of G quadruplex-mediated epigenetic instability in REV1-deficient cells EMBO Journal 33, 2507-20. ... Nature Biotechnology 20, 1129-1134. PMID:12379869. -
Primitive genetic alphabet based on RNA and DNA - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/primitive-genetic-alphabet-based-on-rna-and-dna/3 Jun 2020: New research suggests that DNA building blocks may have coexisted with RNA at the dawn of life
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First complete atomic model of condensin lays foundation for…
https://www2.mrc-lmb.cam.ac.uk/first-complete-atomic-model-of-condensin-lays-foundation-for-understanding-chromosome-compaction/14 Jul 2020: Although Jan’s group has been working on SMC complexes for about 20 years, it has been hard to even understand what they do with DNA in cells and determining the
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Engaging with the public while social distancing - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/engaging-with-the-public-while-social-distancing/14 Apr 2020: Between them, Nathan, Xiaohan, and Jennifer took part in more than 20 live chats and answered more than 60 questions outside the live chats.
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Brain organoids with the potential to predict drug permeability - MRC …
https://www2.mrc-lmb.cam.ac.uk/brain-organoids-with-the-potential-to-predict-drug-permeability/12 Jun 2020: The human brain is bathed in a supportive fluid called the cerebrospinal fluid (CSF) that provides various nutrients. Madeline Lancaster’s group have now developed a new brain organoid that produces CSF and has the potential to predict whether
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Studying the spike protein of SARS-CoV-2 - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/studying-the-spike-protein-of-sars-cov-2/18 Aug 2020: And now it is past 20 million, with more than 0.7 million deaths.
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A cellular pacemaker in the central body clock - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/a-cellular-pacemaker-in-the-central-body-clock/7 Jul 2020: Although many of the cells in our bodies have their own local clocks, the principal circadian clock is the SCN, a network of approximately 20,000 cells in the hypothalamus.
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High-resolution structure of a GPCR-arrestin complex - MRC Laboratory …
https://www2.mrc-lmb.cam.ac.uk/first-high-resolution-structure-of-a-gpcr-arrestin-complex/17 Jun 2020: Understanding minute structural differences in (G protein-coupled receptor) GPCR complexes could lead to the design of more efficacious drugs that have fewer side effects
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Max Perutz Lecture to be given by John Diffley - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/max-perutz-lecture-to-be-given-by-john-diffley/20 Feb 2020: 20 February, 2020. Francis Crick Institute. ‘How our chromosomes are replicated’ is the title of the 2019 Max Perutz Lecture to be given by John Diffley on Wednesday 26th February at
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Daffodils announce LMB staff's fundraising for Marie Curie - MRC…
https://www2.mrc-lmb.cam.ac.uk/daffodils-announce-lmb-staffs-fundraising-for-marie-curie/23 Mar 2020: And this month, during the Great Daffodil Appeal by Marie Curie, Freda collected another £155.05, bring the total to £695.20.
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