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AOC Minutes 20th November 2020
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_20.11.20_redacted.pdf14 May 2024: Minutes. Date Friday, 20/11/2020 Time 1.30pm. To Committee Members At Held virtually using MS Teams. -
AOC Minutes 24th January 2020
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_24.01.20_redacted.pdf14 May 2024: asked for clarification on charging. Anything which means the technician is going above and beyond for more than approximately 20 minutes should be charged for but will release a clarification statement -
r of replacement
https://www.ubs.admin.cam.ac.uk/files/r_of_replacement.pdf18 Aug 2015: 20. Slide 20: Why replace animals? - Policies of funders and journals. ... 1http://www.lasa.co.uk/PDF/Guidance%20notes%20RR%20(2004).pdf. See also:. http://www.rspca.org.uk/sciencegroup/researchanimals/ethicalreview/retrospectivereview. 28. Slide 29: -
AOC Minutes 18th December 2020
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_18.12.20_redacted.pdf14 May 2024: reported there are 20 desktop computers available and will be distributed on a first come, first serve basis. -
PPL number: | Granted: 28 May 20 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_controlling_immune_cell_killing_nts_redacted.pdf19 Aug 2021: What's the aim of this project? PPL number: | Granted: 28 May 20 | Expires: 28 May 25. ... In this project we. PPL number: | Granted: 28 May 20 | Expires: 28 May 25. -
Page 1 of 23 University Biomedical Services University Biomedical ...
https://www.ubs.admin.cam.ac.uk/files/awhandbook_2015.pdf25 Sep 2015: ASC The Animals in Science Committee – the independent, non-departmental public body set up under ASPA sections 19 and 20. ... concerns. Page 20 of 23. 13. AWERB Standing Committee Terms of Reference. -
PPL number: | Granted: 06 Jan 20 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/support_procedures_for_neural_repair_nts_redacted.pdf19 Aug 2021: What's the aim of this project? PPL number: | Granted: 06 Jan 20 | Expires: 06 Jan 25. ... Protocol 1. Mild all animals. Protocol 2. Moderate all animals. PPL number: | Granted: 06 Jan 20 | Expires: 06 Jan 25. -
1 Responsibility in the use of animals in bioscience ...
https://www.ubs.admin.cam.ac.uk/files/animals_in_research.pdf8 Jan 2015: These should be tailored to individual projects, based on experience with the animal model and/or species and incorporating humane endpoints as appropriate (see page 20). ... RIGHT: Group-housed rabbit in an enriched floor pen. Novo Nordisk. 20. -
PPL number: | Granted: 21 Jan 20 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/the_long-term_effects_of_developmental_hypoxia_on_cardiac_function_nts_redacted.pdf19 Aug 2021: PPL number: | Granted: 21 Jan 20 | Amended: 02 Aug 21 | Expires: 21 Jan 25. ... What's the aim of this project? PPL number: | Granted: 21 Jan 20 | Amended: 02 Aug 21 | Expires: 21 Jan 25. -
PPL number: | Granted: 20 Nov 19 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/neural_basis_of_spatial_cognition_and_memory_in_the_hippocampus_nts_redacted.pdf20 Aug 2021: All surgical. PPL number: | Granted: 20 Nov 19 | Expires: 20 Nov 24. ... Reduction. PPL number: | Granted: 20 Nov 19 | Expires: 20 Nov 24. -
PPL number: | Granted: 20 Aug 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/training_in_advanced_or_complex_procedures_or_devices_nts_redacted.pdf13 Sep 2021: Education and training licence. PPL number: | Granted: 20 Aug 21 | Expires: 20 Aug 26. ... A retrospective assessment of these aims will be due by 20 February 2027. -
PPL number: | Granted: 18 Feb 20 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/protection_after_heart_attack_or_stroke_nts_redacted.pdf19 Aug 2021: PPL number: | Granted: 18 Feb 20 | Amended: 11 Mar 21 | Expires: 18 Feb 25. ... disability. PPL number: | Granted: 18 Feb 20 | Amended: 11 Mar 21 | Expires: 18 Feb 25. -
PPL number: | Granted: 01 Dec 20 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/radiation_combinations_for_cancer_treatment_nts_redacted.pdf19 Aug 2021: PPL number: | Granted: 01 Dec 20 | Amended: 01 Dec 20 | Expires: 01 Dec 25. ... Objectives and benefits. PPL number: | Granted: 01 Dec 20 | Amended: 01 Dec 20 | Expires: 01 Dec 25. -
Code of Practice for the Housing and Care of ...
https://www.ubs.admin.cam.ac.uk/files/cop_housing_care_for_sci_purp.pdf18 Sep 2015: rpos. esC. onte. nts 2 Rats 19. 2.1 Accommodation specifications 193 Gerbils 20 – 21. ... 20 Council Directive 91/629/EEC of 19 November 1991 laying down minimum standards for the protection of calves. -
PPL number: | Granted: 26 Nov 20 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/ischaemia_reperfusion_injury_and_organ_transplantation_nts_redacted.pdf19 Aug 2021: Objectives and benefits. PPL number: | Granted: 26 Nov 20 | Expires: 26 Nov 25. ... The total number of transplants performed also fell, ranging from a 3% decline for pancreas transplants to 20% for lung or heart-lung transplants. -
PPL number: | Granted: 24 Sep 20 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_role_of_physical_cues_in_nervous_system_function_in_wild_type_and_transgenic_anima_redacted.pdf19 Aug 2021: PPL number: | Granted: 24 Sep 20 | Amended: 05 Feb 21 | Expires: 24 Sep 25. ... Objectives and benefits. PPL number: | Granted: 24 Sep 20 | Amended: 05 Feb 21 | Expires: 24 Sep 25. -
PPL number: | Granted: 13 Jan 20 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/molecular_and_genetic_regulation_of_glial_development_and_function_nts_redacted.pdf19 Aug 2021: Objectives and benefits. PPL number: | Granted: 13 Jan 20 | Expires: 13 Jan 25. ... If we. PPL number: | Granted: 13 Jan 20 | Expires: 13 Jan 25. -
PPL number: | Granted: 23 Oct 20 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/evaluation_of_novel_strategies_for_bone_repair_nts_redacted.pdf19 Aug 2021: Objectives and benefits. PPL number: | Granted: 23 Oct 20 | Expires: 23 Oct 25. ... Who or what will benefit from these outputs, and how? PPL number: | Granted: 23 Oct 20 | Expires: 23 Oct 25. -
PPL number: | Granted: 18 Nov 20 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/papillomavirus_transmission_infection_and_lesion_formation_nts_redacted.pdf19 Aug 2021: Who or what will benefit from these outputs, and how? PPL number: | Granted: 18 Nov 20 | Expires: 18 Nov 25. ... months. PPL number: | Granted: 18 Nov 20 | Expires: 18 Nov 25. -
AOC Minutes 24th July 2020
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_24.07.20_redacted.pdf14 May 2024: Minutes. Date Friday, 24/07/2020 Time 1.30pm. To Committee Members At Held virtually using MS Teams. Subject AWERB Operations Committee Attendees:. Apologies:. Mentioned within text:. 1. Minutes The minutes from the meeting held on 26th June 2020 -
AOC Minutes 22nd May 2020
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_22.05.20_redacted.pdf14 May 2024: Minutes. Date Friday, 22/05/2020 Time 1.30pm. To Committee Members At Held virtually using MS Teams. Subject AWERB Operations Committee Attendees:. Apologies: Mentioned within text: 1. Minutes The minutes were approved. 2. Matters arising None. 3. -
AOC Minutes 25th September 2020
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_25.09.20_redacted.pdf14 May 2024: Minutes. Date Friday, 25/09/2020 Time 1.30pm. To Committee Members At Held virtually using MS Teams. Subject AWERB Operations Committee Attendees:. Apologies:. Mentioned within text:. 1. Minutes The minutes from the meeting held on 24th July 2020 -
PPL number: | Granted: 25 Mar 21 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/circuit_mechanisms_of_learning_and_memory_in_the_mammalian_brain_nts_expires2026_redacted.pdf13 Sep 2021: Mice: Non-recovery - 20%. Mild - 65%. Moderate - 15%. What will happen to animals at the end of this project? ... Typically, we would need at least 20 animals in each of two groups to be reasonably safe to detect a difference between the two groups. -
Determining mechanisms of tumour development and relapse following…
https://www.ubs.admin.cam.ac.uk/system/files/public/determining_mechanisms_of_tumour_development_and_relapse_following_treatment_non-technical_summary_redacted.pdf29 Apr 2024: Mouse: moderate 20%. Mouse: Mild 80%. What will happen to animals at the end of this project? -
Profiling of test agents in rodents in a drug discovery platform
https://www.ubs.admin.cam.ac.uk/system/files/public/profiling_of_test_agents_in_rodents_in_a_drug_discovery_platform_non-technical_summary_redacted.pdf30 Apr 2024: In addition, we expect to run a minimum of 20. PPL number: | Granted: 03 Feb 22 | Amended: 08 Nov 23 | Expires: 03 Feb 27. ... The animal will then be put under brief anaesthesia (typically for 20 minutes, maximum of one hour) in order to take images of -
Neural, physiological and behavioural mechanisms underlying cognition …
https://www.ubs.admin.cam.ac.uk/system/files/public/neural_physiological_and_behavioural_mechanisms_underlying_cognition_and_emotion_non-technical_sum_redacted.pdf30 Apr 2024: All animals will first receive short, behavioural tests in the home cage that last no more than 20 mins, to determine their trait anxiety. ... Subsequently, having received i or ii, adult or juvenile marmosets will receive drugs peripherally (typically 20 -
Investigating the niche of mucosal parasitic nematodes and their…
https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_niche_of_mucosal_parasitic_nematodes_and_their_interactions_with_their_hosts_non_redacted.pdf30 Apr 2024: muris) eggs or larvae. A high dose (200-3000 eggs/larvae) recreates an acute infection, where mice expel the worms after 2 weeks, and a low dose (20 eggs) recreates a -
AOC Minutes 26th June 2020
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_26.06.20_redacted.pdf14 May 2024: Minutes. Date Friday, 26/06/2020 Time 1.30pm. To Committee Members At Held virtually using MS Teams. Subject AWERB Operations Committee Attendees:. Apologies:. Mentioned within text: 1. Minutes The minutes from the meeting held on 22nd May 2020 were -
Provision of an outsourced drug discovery platform for the…
https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_the_development_of_therapeutic_drugs_for_neur_redacted.pdf30 Apr 2024: Mice:. Mild 35%. Moderate 65%. Rats:. Mild 20%. Moderate 80%. What will happen to animals at the end of this project? -
Cancer and its microenvironment! From mechanisms to translation…
https://www.ubs.admin.cam.ac.uk/system/files/public/cancer_and_its_microenvironment_from_mechanisms_to_translation_non-technical_summary_redacted.pdf30 Apr 2024: and a minimum practicable difference between groups of 20-25%. -
AOC Minutes 21st February 2020
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_21.02.20_redacted.pdf14 May 2024: Minutes. Date Friday, 21/02/2020 Time 1.30pm. To Committee Members At Meeting Room, 1st Floor, Greenwich House. Subject AWERB Operations Committee Attendees:. Apologies:. Mentioned within text:. 1. Minutes The minutes were approved after minor -
PPL number: | Granted: 14 Jul 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/the_role_of_transposable_elements_in_cichlid_fish_development_and_evolution_nts_redacted.pdf13 Sep 2021: Immediately after, the eggs will be returned to aquaria. Injection of a batch of 25 eggs takes less than 20 minutes. -
PPL number: | Granted: 08 Mar 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/oxygen_sensing_and_nutrient_signalling_in_metabolic_disease_redacted.pdf18 Jun 2021: In order to address the scientific questions here, we estimate that we will need to run up to 20-25 separate studies. -
PPL number: | Granted: 02 Feb 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/ageing_and_therapy_in_mouse_models_for_neurodegenerative_diseases_redacted_0.pdf18 Jun 2021: therapy. For the past 20 years, our lab has produced several genetically modified mouse models that develop clumping of aSynuclein and tau that replicate key aspects of human disease, such as -
Extrinsic regulation of haematopoietic stem and progenitor cells in…
https://www.ubs.admin.cam.ac.uk/system/files/public/extrinsic_regulation_of_haematopoietic_stem_and_progenitor_cells_in_health_disease_and_as_a_therape_1_redacted.pdf30 Apr 2024: Species Severity Proportion of animals. Mice Sub-threshold 20%. Mice Mild 65%. -
Concordat on Openness on Animal Research in the UKAnnual ...
https://www.ubs.admin.cam.ac.uk/sites/www.ubs.admin.cam.ac.uk/files/concordat-on-openness-annual-report-2023.pdf15 Nov 2023: Introduction 10. About this report 18. PART 1: PROGRESS IN OPENNESS ON ANIMAL RESEARCH IN THE UK 20. ... Progress in openness on animal research in the UK. PARTONE. Understanding Animal Research 20. -
Provision of an outsourced drug discovery platform for the…
https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_the_development_of_therapeutic_drugs_for_canc_redacted.pdf30 Apr 2024: An estimated 20% of mice of strain NSG will show swelling around the hocks. -
PPL number: | Granted: 10 Sep 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/cellular_and_molecular_mechanisms_of_the_mouse_embryo_development_nts_redacted.pdf13 Sep 2021: Page 6 of 11. Mild 100% 100% 80% 0%. Moderate0% 0% 20% 100%. -
AOC Minutes 24th April 2020
https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_24.04.20_redacted.pdf14 May 2024: Minutes. Date Friday, 24/04/2020 Time 1.30pm. To Committee Members At Held using Microsoft Teams. Subject AWERB Operations Committee Attendees:. Apologies:. Mentioned within text:. 1. Minutes The minutes from the meeting held on Friday 21st February -
PPL number: | Granted: 10 Jun 19 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_diseases_with_an_inflammatory_component_nts_expires2022_redacted.pdf13 Sep 2021: NASH, a severe form NAFLD, is most likely to become the primary reason why patients will require a liver transplant over the next 10-20 years. ... In January 2021, an additional 1800 mice were added to protocol 5 and 500 rats were added to protocol 20, -
PPL number: | Granted: 16 Jul 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/developing_therapeutic_drugs_for_cancer_including_the_establishment_of_tumour_models_nts_redacted.pdf13 Sep 2021: The maximum number of times an animal may undergo anesthesia in order to be imaged is 5 times within a 7 day period, or 20 times in total over the -
AWERB 3Rs Minutes 3rd January 2024
https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_030124_redacted.pdf30 Apr 2024: 8. Minutes of the AOC meeting 20/10/23 The minutes were noted. -
PPL number: | Granted: 28 Jun 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/epithelial_stem_cell_behaviour_away_from_homeostasis_translational_relevance._nts_redacted.pdf13 Sep 2021: 4. When baby mice (mice that have not been weaned) undergo a procedure (typical duration of 5-20 minutes), they are returned with their brothers and sisters to their mother immediately -
PPL number: | Granted: 12 Nov 20 | Amended: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/discovery_of_novel_compounds_for_the_treatment_of_dementia._nts_redacted.pdf19 Aug 2021: PPL number: | Granted: 12 Nov 20 | Amended: 16 Nov 20 | Expires: 12 Nov 25. ... There may be unwanted effects of. PPL number: | Granted: 12 Nov 20 | Amended: 16 Nov 20 | Expires: 12 Nov 25. -
PPL number: | Granted: 30 Mar 21 | Expires: ...
https://www.ubs.admin.cam.ac.uk/system/files/public/investigation_of_normal_haematopoietic_stem_cell_subversion_and_the_evolution_maintenance_and_targeting_of_haematological_malignancies_redacted.pdf18 Jun 2021: These mice will be put under for 20-30 minutes, using an anaesthetic (inducing a state of a deep sleep). ... The mice are expected to recover from anaesthesia within 20-30 minutes at most and no long-term effects are expected. -
AWERB 3Rs Minutes 3rd May 2023 Redacted
https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_030523_redacted.pdf14 May 2024: Protocols 9, 10 & 20. • Protocols 9, 11, 12, 15, 16. -
AWERB 3Rs Minutes 7th June 2023 Redacted
https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_070623_redacted.pdf14 May 2024: 7. Standard condition 18 reports. 20/01/23 There have been 10 SC18 since the last meeting. -
3Rs Minutes 6th January 2021 Redacted
https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_060121_redacted.pdf14 May 2024: 20 06 2019_sc18 • In section 3.5, what do the numbers in brackets refer to? -
3Rs Minutes 7th October 2020 Redacted
https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_071020_redacted.pdf14 May 2024: In 2.4 it is noted that “20% of the animals were found dead” – yet none are returned as being anything other than mild in the protocol table 2.1: please -
AWERB 3Rs Minutes 7th December 2022 Redacted
https://www.ubs.admin.cam.ac.uk/system/files/public/3rs_minutes_071222_redacted.pdf14 May 2024: 7. Standard condition 18 reports. 20 new SC 18 reports submitted since last AWERB 3Rs meeting – [nothing to discuss].
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