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LMB 365 - Day 20 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-20/20 Jan 2019: Published on. 20 January, 2019. The first research undertaken at the MRC Unit in Cambridge, that later was renamed the LMB, was the work to determine the structure of proteins. ... Here, on day 20 of #LMB365, is the model of the first protein whose -
LMB 365 - Day 284 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-284/11 Oct 2019: Every year 20-30 new graduates from the UK and all over the world join the LMB PhD programme. -
LMB 365 - Day 191 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-191/10 Jul 2019: Day 191 of #LMB365 shows some of the cakes they baked, which helped raise £51.20 for this worthy cause. -
Bob Sheppard 1932 – 2019 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/bob-sheppard-1932-2019/25 Jan 2019: Bob Sheppard at the LMB. Robert (Bob) Sheppard, Head of the Sub-Division of Peptide Chemistry, in the LMB’s PNAC Division for over 20 years and internationally recognised in the ... Bob officially retired in April 1991, having been leader of the very -
LMB 365 - Day 24 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-24/24 Jan 2019: During the construction of the building the planning department had a concern that the towers would be too shiny so made the contractor build a 20 foot high section that was -
LMB 365 - Day 113 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-113/22 Apr 2019: Published on. 23 April, 2019. The external mounds around the LMB were originally planted with 20 different wild flora species to produce a grassland meadow mixture. -
LMB 365 - Day 354 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-354/20 Dec 2019: Published on. 20 December, 2019. On day 354 of #LMB365, members of the LMB celebrate Christmas Jumper Day – bringing in the holidays in style! -
LMB 365 - Day 324 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-324/20 Nov 2019: Published on. 20 November, 2019. This image for day 324 of #LMB365 shows a cryo-EM visualisation of a G protein-coupled receptor reconstituted into a lipid nanodisc and then coupled -
LMB 365 - Day 263 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-263/20 Sep 2019: Published on. 20 September, 2019. Much of the research at the LMB must be conducted in carefully controlled conditions of temperature, vibration and magnetic fields. -
LMB 365 - Day 293 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-293/20 Oct 2019: Published on. 20 October, 2019. Day 293 of #LMB365 shows the new public art outside the recently opened Jeffrey Cheah Biomedical Centre. -
LMB 365 - Day 79 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-79/19 Mar 2019: Published on. 20 March, 2019. This drawing for day 79 of #LMB365 is by Paul Margiotta #piljammin in the LMB’s Visual Aids team. -
LMB 365 - Day 201 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-201/20 Jul 2019: Published on. 20 July, 2019. A crocheted stag’s head looks out into the atrium on day 201 of #LMB365 giving a glimpse of this years Art and Craft show. -
LMB 365 - Day 110 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-110/19 Apr 2019: Published on. 20 April, 2019. On day 110 of #LMB365 Soudabeh Imanikia in the Neurobiology Division took advantage of fluorescently labelled Caenorhabditis elegans worms to make them spell our name! -
LMB 365 - Day 140 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-140/19 May 2019: Published on. 20 May, 2019. On day 140 of #LMB365 we have a picture by Katja Röper in the Cell biology Division. -
LMB 365 - Day 51 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-51/19 Feb 2019: Published on. 20 February, 2019. Day 51 of #LMB365 shows the embryonic germ cells of the mouse. -
LMB 365 - Day 171 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-171/20 Jun 2019: Published on. 20 June, 2019. Day 171 of #LMB365 shows Richard Henderson with a model of the membrane protein, bacteriorhodopsin. -
LMB 365 - Day 232 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-232/20 Aug 2019: Published on. 20 August, 2019. The LMB’s NMR facility is home to five of the LMB’s seven NMR spectrometers, and is also currently hosting a spectrometer for our future -
Sydney Brenner (1927 - 2019) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/sydney-brenner-1927-2019/5 Apr 2019: He was a key member of the LMB for 30 years, 20 of which he shared an office and ideas with Francis Crick. ... Sydney had an extraordinary career, played a key role throughout the early days and development of molecular biology and is one of the greatest -
Meetings
https://www2.mrc-lmb.cam.ac.uk/groups/aberto/meetings.html5 Jul 2019: Quality control in Life Processes. Frankfurt. Germany. June 20-22. ... Cambridge. UK. 15-20 Feb. -
John Kendrew Lecture to be given by Brenda Schulman - MRC Laboratory…
https://www2.mrc-lmb.cam.ac.uk/john-kendrew-lecture-to-be-given-by-brenda-schulman/26 Sep 2019: Members of the large family of CRLs are responsible for 20% of all cellular ubiquitylation, regulate virtually all eukaryotic processes, and serve as one of the hottest drug discovery platforms in ... In my talk, I will describe our findings that reveal -
LMB welcomes Kelly Nguyen as a new Group Leader - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/lmb-welcomes-kelly-nguyen-as-a-new-group-leader/20 Jun 2019: 20 June, 2019. The LMB is delighted to announce the appointment of Kelly Nguyen as a Group Leader in the LMB’s Structural Studies Division. -
How and why researchers should engage with Parliament - MRC…
https://www2.mrc-lmb.cam.ac.uk/how-and-why-researchers-should-engage-with-parliament/20 Nov 2019: How and why researchers should engage with Parliament. Published on. 20 November, 2019. -
LMB staff raise over £1500 for The Cystic Fibrosis Trust - MRC…
https://www2.mrc-lmb.cam.ac.uk/lmb-staff-raise-over-1500-for-the-cystic-fibrosis-trust/20 Dec 2019: 20 December, 2019. John O’Neill, presents Jessica Barnard and Sandra Howarth of The Cystic Fibrosis Trust with the LMB’s donation. -
Winners of the LMB’s annual Science Image Award - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/the-winner-of-the-2019-lmbs-schools-science-image-award/1 Aug 2019: The sense of amazement was fantastic.”. The Science Image Award will be running again in the 2019/20 academic year. -
Coot Cryo-EM Practical
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/tutorial/Coot-Cryo-EM.html8 Aug 2019: wait}. On reading the new mtz file:. – In Amplitudes: choose FoutBlur_20.0. – -
Creating an entire bacterial genome with a compressed genetic code -…
https://www2.mrc-lmb.cam.ac.uk/creating-an-entire-bacterial-genome-with-a-compressed-genetic-code/16 May 2019: 61 of these codons code for the 20 different amino acids used to build proteins and three function as full-stops to terminate production of a protein. -
How chromosomes are bound to be separated in cell division - MRC…
https://www2.mrc-lmb.cam.ac.uk/how-chromosomes-are-bound-to-be-separated-in-cell-division/3 Oct 2019: A unique feature of Cenp-A nucleosomes is that the DNA coiled around it is unwrapped by 20 base-pairs at each end. -
LMB raises £1,108 for cancer support and a children’s ambulance - MRC …
https://www2.mrc-lmb.cam.ac.uk/lmb-raises-1108-for-cancer-support-and-a-childrens-ambulance/3 Oct 2019: This amount could be used to run a small Macmillan information and support centre for over 20 hours, helping people affected by cancer to find critical information, advice and support at -
Felix Randow elected Fellow of the Academy of Medical Sciences - MRC…
https://www2.mrc-lmb.cam.ac.uk/felix-randow-elected-fellow-of-the-academy-of-medical-sciences/8 May 2019: Felix becomes the 20. th . LMB scientist honoured by the Academy of Medical Sciences since its foundation in 1998. -
Benjamin Falcon discusses his research in Neuronet’s first newsletter …
https://www2.mrc-lmb.cam.ac.uk/benjamin-falcon-discusses-his-research-in-neuronets-first-newsletter/20 Sep 2019: 20 September, 2019. LMB’s newly recruited Group Leader weighs in on various aspects of Alzheimer’s Disease, from the clinical implications of deciphering Tau filaments in brains of people suffering -
Publications
https://www2.mrc-lmb.cam.ac.uk/groups/aberto/Publications.html5 Jul 2019: Dementia Forum 5, 17–20. Bertolotti A. (2011). Glucose levels are partly regulated through the alteration of protein synthesis induction. -
Current Developments in Coot for Macromolecular Model Building…
https://www2.mrc-lmb.cam.ac.uk/coot/protein-science/Casanal_Lohkamp_Emsley_11112019-pe-2.pdf11 Nov 2019: 20. Although writing multi-threaded code is difficult, the pay-off is substantial. ... Acta Crystallogr. D Biol. Crystallogr. 68:368–380. 20. Schröder GF, Levitt M, Brunger AT (2010) Super-resolution biomolecular crystallography with low-resolution -
Robotic crystallisation: References
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/WWWrobots/references.html31 Jul 2019: Drug Discov Today 21, 819-825. LMB 20: F Gorrec (2015) The MORPHEUS II protein crystallisation screen. -
Model-Building with Modern Coot Paul Emsley Scripps, Feb 2019 ...
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/presentations/Coot-Scripps-Feb-2019-EOS.pdf21 Feb 2019: Slide 17. Slide 18. Slide 19. Slide 20. Slide 21. Slide 22. -
If you want to download entire dataset, please contact Bill Schafer.…
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/WormBehaviorDatabase.tmp.html14 Oct 2019: 972 JU345 on food R_2011_03_17__15_20_20__8. JU345. C. elegans wild isolate. anticlockwise. ... hermaphrodite. young adult. 30minutes. 2011-03-17 15:20:20. OP50. 627nm. 22C. No treatment. -
Mechanism of ribosome stalling during translation of a poly(A) tail
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/NSMB_2019.pdf25 Nov 2019: A-siteP-site STOP. Testsequence. a. 20 40. Time (min). 600. 20. 40. ... Nat. Rev. Mol. Cell Biol. 20, 406–420 (2019). 5. van Hoof, A. & -
Madeline Lancaster Fixation, cryosectioning and immunostaining brain…
https://www2.mrc-lmb.cam.ac.uk/groups/lancaster/download/Analyzing-brain-organoids.docx1 Aug 2019: Fix at 4C for 15-20 min. 2. Wash 3X for 10 min in PBS. -
Activation of GCN2 by the ribosomal P-stalk
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/PNAS_2019.pdf7 Mar 2019: Upon deletion of the CTD (construct C), GCN2’sbasal activity increased 20-fold (Fig. ... 0.001 0.01 0.1 1 10 1000. 10. 20. 30. 40. Time (min). % -
The structure of bactofilin filaments reveals their mode of membrane…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Deng2019Natmicro.pdf26 Aug 2019: 80. 85. 90. 95. 5. 15. 5. 20. 15 80 85 90 95. ... in a 45 Ti rotor (Beckman) for 30 min at 4 C, followed by another centrifugation at 20,000 r.p.m. -
The ER membrane protein complex promotes biogenesis of sterol-related …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/JCS_2019.pdf18 Jan 2019: A) WT and ΔEMC6 (Δ6) cells were exposed to Chol:MBCD (25, 37.5 and50 µM, 20 h) and visualised by staining with Crystal Violet. ... or without 10 µM avasimibe (AVA, 20 h)and visualised by staining with Crystal Violet. -
Articleshttps://doi.org/10.1038/s41594-019-0196-z 1MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Burmann%202019%20NSMB.pdf4 Mar 2019: 20 nm. 20 nm. 20 nm. 20 nm. 20 nm. 20 nm 20 nm 20 nm. ... 20 nm 20 nm 20 nm20 nm. 20 nm 20 nm 20 nm. -
Biallelic Variants in ASNA1, Encoding a Cytosolic Targeting Factor of …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/CircGen_2019.pdf1 Dec 2019: Both missense variants were predicted to be del-eterious (CADD >20 and M-CAP >0.025). ... buffer supplemented with 20 mM imidazole, and eluted with lysis buffer supplemented with 250 mM. -
TTC5 mediates autoregulation of tubulin via mRNA degradation
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2019.pdf19 Nov 2019: Methods Mol. Biol. 619, 339–363 (2010). doi:10.1007/978-1-60327-412-8_20 Medline. 36. Q. Feng, S. ... Shao, In vitro reconstitution of translational arrest pathways. Methods 137, 20–36 (2018). -
15591370691369 1..30
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/elife_2019.pdf29 May 2019: body binding is 4.4% (i.e., 20-fold less than our fluorescence standard). ... 20. 40. 60. 80. 0. Nb uptake by GFP-PrP. (Tg x 2h). -
Sub ForwardPrimer() ' ' ForwardPrimer Macro ' '…
https://www2.mrc-lmb.cam.ac.uk/groups/cartera/download/resources/computer/word_macros/UsefulMacros.docx25 Jan 2019: Sub ForwardPrimer(). '. ' ForwardPrimer Macro. '. '. Selection.MoveRight Unit:=wdCharacter, Count:=20, Extend:=wdExtend. ... Selection.Font.Underline = wdUnderlineSingle. Selection.MoveLeft Unit:=wdCharacter, Count:=1. End Sub. Sub ReversePrimer(). '. ' -
Recognition and Degradation of Mislocalized Proteins in Health and…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/CSHL_Persp_2019.pdf8 Mar 2019: Recognition and Degradation of MislocalizedProteins in Health and Disease. Ramanujan S. Hegde and Eszter Zavodszky. Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom. Correspondence: -
Crystal Structures and Nuclear Magnetic Resonance Studies of the Apo…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/WWWrobots/PDF/Publications/acs.biochem.9b00296.pdf31 Jul 2019: The cells were lysed via sonication, and the lysate wascleared by centrifugation at 18000 rpm for 20 min. ... Dev. 20, 9195.(17) Soucek, L., Whitfield, J., Martins, C. P., Finch, A. -
Cryo‐EM structure of the MinCD copolymeric filament from Pseudomonas…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Szewczak-Harris_et_al-2019-FEBS_Letters.pdf22 Jul 2019: and therefore its dissociation from the membrane. [19,20]. Released MinD will then undergo exchange of. ... spatially regulate cytokinesis. Cell 146, 396–407.20 Vecchiarelli AG, Li M, Mizuuchi M, Hwang LC,. -
Structural Analysis of the Interaction between the BacterialCell…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/mBio-2018-Kureisaite-Ciziene-e01346-18.full.pdf5 May 2019: 10 20 30 40 50 60 70 80 90 1000.0. 0.2. ... obab. ility FtsB. 20 40 60 80 100 1200.0. 0.2. 0.4.
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