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  2. Join us!

    https://www2.mrc-lmb.cam.ac.uk/groups/randow/Join_us%21.html
    23 Apr 2014: Each year LMB recruits about 20 PhD students. Students register for their PhD with the University of Cambridge and belong to one of its colleges.
  3. Anne Bertolotti awarded the 2014 Hooke Medal - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/anne-bertolotti-awarded-the-2014-hooke-medal/
    Thumbnail for Anne Bertolotti awarded the 2014 Hooke Medal - MRC Laboratory of Molecular Biology 20 Jan 2014: Published on. 20 January, 2014. Anne Bertolotti, from the LMB’s Neurobiology Division, has been announced as the British Society for Cell Biology 2014 Hooke Medal winner.
  4. Research collaboration between LMB and AstraZeneca - MRC Laboratory…

    https://www2.mrc-lmb.cam.ac.uk/research-collaboration-between-lmb-and-astrazeneca/
    Thumbnail for Research collaboration between LMB and AstraZeneca - MRC Laboratory of Molecular Biology 20 May 2014: Published on. 20 May, 2014. The Reuters news agency reports further detail of a joint research fund between the MRC Laboratory of Molecular Biology and AstraZeneca.
  5. JCSG+ Screen

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB12.pdf
    2 Oct 2014: 20 0.2 M Li2SO4 8% PEG 20,000 8% PEG 500 MME. ... 21 0.2 M MgCl2 8% PEG 20,000 8% PEG 500 MME.
  6. Hugh Pelham discusses research collaboration between LMB and…

    https://www2.mrc-lmb.cam.ac.uk/hugh-pelham-discusses-research-collaboration-between-lmb-and-astrazeneca-in-more-depth/
    Thumbnail for Hugh Pelham discusses research collaboration between LMB and AstraZeneca in more depth - MRC Laboratory of Molecular Biology 20 May 2014: Published on. 20 May, 2014. Mike Scialom talks to Sir Hugh Pelham about why pledge from the MRC LMB and AstraZeneca could mean good news for Cambridge. ... This article is no longer available from the source website: Cambridge News 20 May 2014.
  7. Nobel prize winning Cambridge scientist Max Perutz given new stamp of …

    https://www2.mrc-lmb.cam.ac.uk/nobel-prize-winning-cambridge-scientist-max-perutz-given-new-stamp-of-approval/
    Thumbnail for Nobel prize winning Cambridge scientist Max Perutz given new stamp of approval - MRC Laboratory of Molecular Biology 22 May 2014: This article is no longer available from the source website: Cambridge News 20 May 2014.
  8. wiz12b_rigaku_20131116

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB02.pdf
    2 Oct 2014: plate). EB‐W12‐BWell Precipitation Reagent Buffer Salt. A1 20% (w/v) PEG 8000 100 mM CHES/ Sodium hydroxide pH 9.5. ... C11 20% (v/v) 1,4‐butanediol 100 mM Sodium acetate/ Acetic acid pH 4.5.
  9. 2-126 Formulations

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB05.pdf
    2 Oct 2014: 1. 20% w/v Polyethylene Glycol 33502. 20% w/v Polyethylene Glycol 33503. ... 20% w/v Polyethylene Glycol 335016. 20% w/v Polyethylene Glycol 3350 17.
  10. 2-110 Formulations

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB01.pdf
    2 Oct 2014: 20% Polyethylene Glycol 800019. 30% v/v iso-Propanol20. 25% w/v Polyethylene Glycol 400021. ... 20% w/v Polyethylene Glycol Monomethyl Ether 55047. 2.0 M Magnesium Chloride hexahydrate48.
  11. 2-144 Formulations vs 2

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB13.pdf
    2 Oct 2014: 18. None. 19. None. 20. 0.1 M HEPES pH 7.521. None22. ... 20% w/v Polyethylene Glycol 335095. 30% w/v Polyethylene Glycol Monomethyl ether 200096.
  12. 1 Clear StrategyTM Screen I MD1-14 A 6 × ...

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB10.pdf
    2 Oct 2014: 20 0.2 M Li2SO4 8% PEG 20,000 8% PEG 500 MME. ... 21 0.2 M MgCl2 8% PEG 20,000 8% PEG 500 MME.
  13. cryo12b_rigaku_20131116

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB07.pdf
    2 Oct 2014: B2 20% (v/v) PEG 300 100 mM Sodium phosphate dibasic/ Citric acid pH 4.2 200 mM Ammonium sulfate 10% (v/v) Glycerol. B3 50% (v/v) PEG 400 ... 200 mM Sodium chloride. F4 20% (v/v) PEG 300 100 mM Imidazole/ Hydrochloric acid pH 8.0
  14. JCSG+ Screen

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB11.pdf
    2 Oct 2014: 20 0.2 M Li2SO4 8% PEG 20,000 8% PEG 500 MME. ... 21 0.2 M MgCl2 8% PEG 20,000 8% PEG 500 MME.
  15. What next after Academia? Three ways to forge a career away from the…

    https://www2.mrc-lmb.cam.ac.uk/what-next-after-academia-three-ways-to-forge-a-career-away-from-the-bench/
    Thumbnail for What next after Academia? Three ways to forge a career away from the bench - MRC Laboratory of Molecular Biology 20 Jun 2014: Published on. 20 June, 2014. A recent event held at the LMB showed how a PhD in science can lead to various exciting careers outside the lab, including working in Science
  16. Madan Babu awarded the Protein Society’s 2014 Protein Science Young…

    https://www2.mrc-lmb.cam.ac.uk/madan-babu-awarded-the-protein-societys-2014-protein-science-young-investigator-award/
    Thumbnail for Madan Babu awarded the Protein Society’s 2014 Protein Science Young Investigator Award - MRC Laboratory of Molecular Biology 20 Feb 2014: Published on. 20 February, 2014. Madan Babu, from the LMB’s Structural Studies Division, has been announced as the recipient of the Protein Society’s 2014 Protein Science Young Investigator Award.
  17. 2-213 Formulations

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB04.pdf
    2 Oct 2014: pH. 4 5 6 7 8 9. 5. 10. 20. 30. ... pH. 4 5 6 7 8 9. 10. 20. 40. 65.
  18. Tutorial 3: Probability Theory,Random Variables andDistributions…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/tutorials/probability_theory_random_variables_and_distributions.pdf
    26 Mar 2014: In a wine cellar, on average 20% of the bottles are not good. ... 2. Out of 20 bottles, what is the probability that at least 16 bottles are stillgood?
  19. elifesciences.org van den Ent et al. eLife 2014;3:e02634. DOI: ...

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/mrebdouble2014.pdf
    6 Jun 2014: Scale bar: 20 nm.DOI: 10.7554/eLife.02634.008. Biochemistry | Biophysics and structural biology. ... Bar: 200 nm. (B) Cryo-EM image of a lipid tube. Bar: 20 nm.
  20. Tutorial 3: Probability Theory,Random Variables and Distributions –…

    https://www2.mrc-lmb.cam.ac.uk/download/tutorial-3-probability-theory-random-variables-and-distributions-answers/?wpdmdl=18821&refresh=6699321d9a5ca1721315869
    25 Mar 2014: P (A) = 3/8. 5. choose(20,10). Answer: 184756. 6. dbinom(10,20,0.5). Answer: 0.176 (3sf). ... 1-pbinom(7,10,0.8). Answer: 0.678 (3sf). 2. X Bin(20, 0.5). P (X 16) = 1 P (X < 16)= 1 P (X 15).
  21. 1256917combinedsupplement

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Gligoris-SM.pdf
    14 Nov 2014: Nat. Struct. Mol. Biol. 20, 371–379 (2013). Medline doi:10.1038/nsmb.2488. 9. C. ... Mol. Cell 27, 300–310 (2007). Medline doi:10.1016/j.molcel.2007.07.002. 20. C. H. Haering, D.
  22. Descriptive and exploratory statistics

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/lectures/Lecture2_DescrExplo.pptx
    3 Mar 2014: 1500. 2000. Histogram of rn2. rn2. Frequency. 0 10 20 30 40 50. ... 6-4. -20. 24. 6. Normal Q-Q Plot. Theoretical Quantiles. Sam. ple.
  23. elifesciences.org Szwedziak et al. eLife 2014;3:e04601. DOI:…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/FtsZ_Piotr_eLife_2014.pdf
    31 Dec 2014: 2008). Although progress has been exhilarating over that past 20 years or so, some of the most fundamen-tal questions still remain: what happens during FtsZ ring constriction? ... We could detect the filamentous rings in 20 out of 28 dividing cells after
  24. Probability Theory Random Variables and Distributions Rob Nicholls…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/lectures/Lecture3_Probability_Theory.pdf
    10 Mar 2014: Ω={one,two,three, four, five,six}. X :Ω{10,0,20}. P(X = x)=. P({six})=1 6 x = 20. ... pX(x)=. P({six})=1 6 x = 20. P({ four, five})=1 3 x = 0.
  25. Rob Nicholls

    https://www2.mrc-lmb.cam.ac.uk/download/lecture-3-probability-theory/?wpdmdl=18808&refresh=6699321d689d01721315869
    10 Mar 2014: pX(x)= P(X = x). p. X. (x)=P(X=x). pX(x)=. P({six})=1 6 x = 20. ... . . . . . p. X. (x)=. P({six})=16x=20. P({four,five})=13x=0. P({one,two,three})=12x=-10.
  26. JCSG+ Screen

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB15.pdf
    2 Oct 2014: None None 0.1 M Tris 8.5 1.5 M lithium sulfate 20. ... 8.5. 1.5 M lithium sulfate. 20. 0.1 M sodium chloride. None.
  27. Use and misuse of statistics

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/lectures/Lecture1_Intro.pptx
    23 Feb 2014: 20. Introduction to R. R is a multipurpose statistical package. It is freely available from:. ... 14. 15. 16. 17. 18. 19. 20. cric$temp. cric$chrip. 70 75 80 85 90.
  28. ProSMART Tutorial - Part 1

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/tutorials/prosmart_tutorial/files/part_1.html
    14 Apr 2014: Whilst 20-30 cycles may be sufficient in many cases, the example in this tutorial will use 40 cycles. ... Again, we will "ignore hydrogens even if present". This time, set the number of cycles to 20.
  29. supplementary figures 070814 JL

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/scc32014si.pdf
    8 Aug 2014: centric cohesin structures and an increase of GFP signals in the nucleoplasm after 20.
  30. Rob Nicholls

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/lectures/Lecture3_Probability_Theory.pptx
    10 Mar 2014: pX(x)= P(X = x). p. X. (x)=P(X=x). pX(x)=. P({six})=1 6 x = 20. ... . . . . . p. X. (x)=. P({six})=16x=20. P({four,five})=13x=0. P({one,two,three})=12x=-10.
  31. Descriptive and exploratory statistics

    https://www2.mrc-lmb.cam.ac.uk/download/lecture-2-descriptive-statistics-and-exploratory-data-analysis/?wpdmdl=18806&refresh=6699321d054ad1721315869
    3 Mar 2014: 1500. 2000. Histogram of rn2. rn2. Frequency. 0 10 20 30 40 50. ... 6-4. -20. 24. 6. Normal Q-Q Plot. Theoretical Quantiles. Sam. ple.
  32. PowerPoint Presentation

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/ImaginingTheBrain/2014/media/Food_For_Thought.pptx
    30 Apr 2014: The brain requires 20% of resting metabolic consumption (1600 calories/day = 320cals).
  33. Probability Theory Random Variables and Distributions Rob Nicholls…

    https://www2.mrc-lmb.cam.ac.uk/download/probability-theory-random-variables-and-distributions-rob-nicholls/?wpdmdl=18807&refresh=6699321d4fd661721315869
    10 Mar 2014: Ω={one,two,three, four, five,six}. X :Ω{10,0,20}. P(X = x)=. P({six})=1 6 x = 20. ... pX(x)=. P({six})=1 6 x = 20. P({ four, five})=1 3 x = 0.
  34. Madeline A. Lancaster Culturing feeder-dependent human iPS/ES cells…

    https://www2.mrc-lmb.cam.ac.uk/groups/lancaster/download/Culturing-human-ES-and-iPS-cells.docx
    21 Mar 2014: 20 ng/ml bFGF (Add just before use). MEF Media (500 ml) – Store at 4C up to 2 weeks. ... 20 mg Dispase. 40 ml DMEM/F-12. Filtered using 0.22 um filter.
  35. 7 NOVEMBER 2014 • VOL 346 ISSUE 6210 7 ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/90_Shao_S_Science_2014.pdf
    8 Nov 2014: 20, 431 (2014). 7. S. Zhu et al., PLOS Pathog. 9, e1003592 (2013). ... collectively representing 20% of all genes. in a typical eukaryotic genome.
  36. 2-211 Formulations

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB03.pdf
    2 Oct 2014: pH. 4 5 6 7 8 9. 0. 10. 20. 30.
  37. pone.0107211 1..10

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/leoa2014.pdf
    3 Sep 2014: Healthcare) in 20 mM Tris, 100 mM NaCl, 1 mM EDTA, 1 mM. ... sucrose, 1 mM EDTA, 20 mM Tris pH 7.6. The cells were stored.
  38. Use and misuse of statistics

    https://www2.mrc-lmb.cam.ac.uk/download/lecture-1-introduction-use-and-misuse-of-statistics/?wpdmdl=18805&refresh=6699321caec5b1721315868
    23 Feb 2014: 20. Introduction to R. R is a multipurpose statistical package. It is freely available from:. ... 14. 15. 16. 17. 18. 19. 20. cric$temp. cric$chrip. 70 75 80 85 90.
  39. Tutorial 3: Probability Theory,Random Variables andDistributions…

    https://www2.mrc-lmb.cam.ac.uk/download/tutorial-3-probability-theory/?wpdmdl=18815&refresh=6699321d818091721315869
    26 Mar 2014: In a wine cellar, on average 20% of the bottles are not good. ... 2. Out of 20 bottles, what is the probability that at least 16 bottles are stillgood?
  40. Elementary hypothesis testing •  Introduction •  Some distributions…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/lectures/Lecture5_hypotheses.pdf
    7 Apr 2014: 0 5 10 15 20 25 30. 0.00. 0.05. 0.10. 0.15. ... 0.20. 0.25. Chisq distribution with various degrees of freedom. x. dchis.
  41. MinCD cell division proteins form alternating copolymeric cytomotive…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/ncomms6341.pdf
    6 Dec 2014: ARTICLE. Received 14 Aug 2014 | Accepted 20 Sep 2014 | Published 15 Dec 2014. ... Lysate was cleared by centrifugation at 20,000 gand the supernatant was loaded on a chitin affinity column.
  42. https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/config.log

    https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/config.log
    10 Dec 2014: This file contains any messages produced by compilers while running configure, to aid debugging if configure makes a mistake. It was created by guile configure 1.8.8, which was generated by GNU Autoconf 2.68. Invocation command line was $.
  43. DOI: 10.1126/science.1256917, 963 (2014);346 Science et al.Thomas G.…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Science-2014-Gligoris-963-7.pdf
    21 Nov 2014: Struct. Mol. Biol. 20, 371–379. (2013).9. C. H. Haering et al., Nature 454, 297–301 (2008).10. ... Ivanov, K. Nasmyth, Mol. Cell 27, 300–310. (2007).20. C. H. Haering et al., Mol.
  44. INVITED REVIEW Mechanosensory molecules and circuits in C. elegans ...

    https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-2.pdf
    10 Dec 2014: neuron, which appears to be unimpor-tant for touch-evoked escape behavior, expresses the neuro-peptide precursor gene flp-20 [43], which has recently been. ... elegans. Learn Mem 20(2):103–108. doi:10.1101/lm.028993.112. 52. Li W, Feng Z, Sternberg PW,
  45. Tutorial 3: Probability Theory,Random Variables and Distributions –…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/tutorials/probability_theory_random_variables_and_distributions_answers.pdf
    25 Mar 2014: P (A) = 3/8. 5. choose(20,10). Answer: 184756. 6. dbinom(10,20,0.5). Answer: 0.176 (3sf). ... 1-pbinom(7,10,0.8). Answer: 0.678 (3sf). 2. X Bin(20, 0.5). P (X 16) = 1 P (X < 16)= 1 P (X 15).
  46. Tutorial 5: Hypothesis TestingRob Nicholls –…

    https://www2.mrc-lmb.cam.ac.uk/download/tutorial-5-hypothesis-testing/?wpdmdl=18817&refresh=6699321e3aeb01721315870
    26 Mar 2014: type I error). For example, suppose that 20 hypothesis tests are per-formed, then clearly it is quite possible that at least one of the tests is significant atthe 95% level,
  47. Tutorial: Introduction to RRob Nicholls – nicholls@mrc-lmb.cam.ac.uk…

    https://www2.mrc-lmb.cam.ac.uk/download/tutorial-introduction-to-r-rob-nicholls-nichollsmrc-lmb-cam-ac-uk-mrclmbstatistics-course-2014/?wpdmdl=18813&refresh=6699321cc811b1721315868
    6 Mar 2014: For example, typing:. (10:20)[3:5]. would return the vector (12,13,14).Note that it is not necessary for index vectors to contain consecutive numbers –. the following sequence of
  48. Rob Nicholls

    https://www2.mrc-lmb.cam.ac.uk/download/lecture-4-statistical-theory/?wpdmdl=18810&refresh=6699321dcbc4c1721315869
    17 Mar 2014: Boxplot:. 20. Continuous Random Variables. Probability Density function:. Cumulative Distribution function:.
  49. Rob Nicholls

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/lectures/Lecture4_Statistical_Theory.pptx
    17 Mar 2014: Boxplot:. 20. Continuous Random Variables. Probability Density function:. Cumulative Distribution function:.
  50. Tutorial: Introduction to RRob Nicholls – nicholls@mrc-lmb.cam.ac.uk…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/tutorials/introduction_to_r.pdf
    6 Mar 2014: For example, typing:. (10:20)[3:5]. would return the vector (12,13,14).Note that it is not necessary for index vectors to contain consecutive numbers –. the following sequence of
  51. Tutorial 5: Hypothesis TestingRob Nicholls –…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_statistics_course_2014/tutorials/hypothesis_testing.pdf
    26 Mar 2014: type I error). For example, suppose that 20 hypothesis tests are per-formed, then clearly it is quite possible that at least one of the tests is significant atthe 95% level,

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