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  2. TRIM21 senses infection and triggers immune response inside cells -…

    https://www2.mrc-lmb.cam.ac.uk/trim21-senses-infection-and-triggers-immune-response-inside-cells/
    Thumbnail for TRIM21 senses infection and triggers immune response inside cells - MRC Laboratory of Molecular Biology 4 Mar 2013: New research, led by Leo James and Will McEwan from the LMB’s PNAC Division, has uncovered a previously unrecognised mechanism of intracellular pathogen
  3. Fred Sanger (1918 – 2013) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/fred-sanger-1918-2013/
    Thumbnail for Fred Sanger (1918 – 2013) - MRC Laboratory of Molecular Biology 20 Nov 2013: Published on. 20 November, 2013. Fred Sanger, double Nobel Laureate and founding member of the LMB in 1962, died on Tuesday 19 November, at the age of 95. ... The “dideoxy” method would shape the way that genomics and biomedicine were explored and
  4. A switch in the brain - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/a-switch-in-the-brain/
    Thumbnail for A switch in the brain - MRC Laboratory of Molecular Biology 20 Dec 2013: Published on. 20 December, 2013. Research from Greg Jefferis’s group in the LMB’s Neurobiology Division has uncovered a biological switch that determines which part of the fruit fly’s
  5. The 12 days of the MRC Centenary - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/the-12-days-of-the-mrc-centenary/
    Thumbnail for The 12 days of the MRC Centenary - MRC Laboratory of Molecular Biology 20 Dec 2013: Published on. 20 December, 2013. 2013 has been a big year for the MRC, marking 100 years since our founding committee met for the first time.
  6. Women in Science Wikipedia Edit-a-thon - MRC Laboratory of Molecular…

    https://www2.mrc-lmb.cam.ac.uk/women-in-science-wikipedia-edit-a-thon/
    Thumbnail for Women in Science Wikipedia Edit-a-thon - MRC Laboratory of Molecular Biology 4 Nov 2013: The day will comprise two parts: an Edit-a-thon workshop for 20 participants and a panel discussion for up to 200 people, led by Mariann Bienz FRS from the LMB
  7. DNA 60th Anniversary celebrated at Cambridge - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/dna-60th-anniversary-celebrated-at-cambridge/
    Thumbnail for DNA 60th Anniversary celebrated at Cambridge - MRC Laboratory of Molecular Biology 25 Apr 2013: The unraveling of the DNA structure has been hailed as one of the most significant landmarks of the 20.
  8. Celebrating ‘100 years of life-changing discoveries’ - MRC Laboratory …

    https://www2.mrc-lmb.cam.ac.uk/celebrating-100-years-of-life-changing-discoveries/
    Thumbnail for Celebrating ‘100 years of life-changing discoveries’ - MRC Laboratory of Molecular Biology 14 Jan 2013: MRC Open Week – from 20-26 June over 35 MRC units, centres and institutes across the UK will be opening their doors to the public or taking science out to the
  9. Greg Winter receives Canada Gairdner International Award - MRC…

    https://www2.mrc-lmb.cam.ac.uk/greg-winter-receives-canada-gairdner-international-award/
    Thumbnail for Greg Winter receives Canada Gairdner International Award - MRC Laboratory of Molecular Biology 20 Mar 2013: Published on. 20 March, 2013. Sir Gregory Winter, from the LMB’s PNAC Division and a former Deputy Director of the LMB, has been awarded a 2013 Canada Gairdner International Award –
  10. 2013 César Milstein Lecture to be given by Scott Emr - MRC Laboratory …

    https://www2.mrc-lmb.cam.ac.uk/2013-milstein-lecture-to-be-given-by-scott-emr/
    Thumbnail for 2013 César Milstein Lecture to be given by Scott Emr - MRC Laboratory of Molecular Biology 20 Sep 2013: 20 September, 2013. Professor Scott Emr will give the 2013 Milstein Lecture on Thursday 26 September at 4.15pm in the LMB’s Max Perutz Lecture Theatre.
  11. Jason Chin inducted into the European Inventor Hall of Fame - MRC…

    https://www2.mrc-lmb.cam.ac.uk/jason-chin-inducted-into-the-european-inventor-hall-of-fame/
    Thumbnail for Jason Chin inducted into the European Inventor Hall of Fame - MRC Laboratory of Molecular Biology 6 Nov 2013: museums. Following the induction in Munich, Jason gave a Solvay Public Lecture for the International Solvay Institutes in Brussels on 20 October 2013.
  12. Exploiting the power of evolution to create designer proteins - MRC…

    https://www2.mrc-lmb.cam.ac.uk/exploiting-the-power-of-evolution-to-create-designer-proteins/
    Thumbnail for Exploiting the power of evolution to create designer proteins - MRC Laboratory of Molecular Biology 15 Nov 2013: Nature 412:921-926 (2001). Cumbers et al. Nature Biotechnology 20:1129-1134 (2002). Primary Sidebar.
  13. Drug developed in Cambridge approved for treatment of multiple…

    https://www2.mrc-lmb.cam.ac.uk/drug-developed-in-cambridge-approved-for-treatment-of-multiple-sclerosis/
    Thumbnail for Drug developed in Cambridge approved for treatment of multiple sclerosis - MRC Laboratory of Molecular Biology 20 Sep 2013: 20 September, 2013. Approval concludes nearly 40-year epic journey from fundamental research, begun at LMB, to discovery of an effective treatment for active relapsing multiple sclerosis.
  14. LMB Crystallography Course April-June 2013 - Literature

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/literature.html
    13 May 2013: Nucleic Acids Research 18(20), 6069-74. Protein Expression:. Studier F.W. (2005) Protein production by auto-induction in high density shaking cultures.
  15. MR_LMB

    https://www2.mrc-lmb.cam.ac.uk/download/molecular-replacement/?wpdmdl=18799&refresh=66993219b7b3a1721315865
    11 Jun 2013: 68 (64) Pack. 24 (2) Refined. 32 (20) RF/TF. 22 (17) Pack.
  16. Structure and superorganization of acetylcholinereceptor–rapsyn…

    https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/pnas13.pdf
    3 Jul 2013: Eulerangle phi and rot were scanned in a range of 20 around the receptor longaxis estimate. ... J Neurosci 20(2):521–528. 8. Marangi PA, et al. (2001) Acetylcholine receptors are required for agrin-inducedclustering of postsynaptic proteins.
  17. pnas201313978 4601..4610

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/pnas2013duman.pdf
    23 Dec 2013: S4C), suggesting that the interacting α-helices are part of theFtsZ binding site.A Dali structural similarity search (20) revealed that the. ... AnezrA-null mutant forms slightly longer cells (20%) comparedwith wild-type cells (23), but an ftsA null
  18. doi:10.1128/mBio.00800-13. 4(6): .mBio. Midcell DNA Translocase FtsK…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/mbio2013bisicchia.pdf
    23 Dec 2013: A single band at 20 kDa is visible, in agreement with the expected size of the protein. ... 3:532–536. 20. Espeli O, Levine C, Hassing H, Marians KJ. 2003.
  19. Cooperative Recruitment of Dynamin and BIN/Amphiphysin/Rvs (BAR)…

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/JBC_Meinecke2013.pdf
    19 Mar 2013: After 20 min at 37 C, the liposomes were centri-fuged at 150,000 g for 20 min. ... Dev. Cell 17,811–822. 20. Sundborger, A., Soderblom, C., Vorontsova, O., Evergren, E., Hinshaw,.
  20. Qrb1300006 1..40

    https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/qrb13.pdf
    30 Jul 2013: 1990). Only when ACh is present for an extended period (greater than about 20 ms), does. ... similarity (20% amino acid identity) with extracellular part of the Torpedo a subunit.
  21. PowerPoint Presentation

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/ImaginingTheBrain/2014/media/Changing_Brains_The_Teenage_Brain_website.pptx
    2 May 2013: Clock time. So, what might we learn from mouse clocks? 20. ... 21. Adolescence and Mental Illness. Approximately 20% of adolescents have a diagnosable mental health disorder.
  22. Deubiquitinases Sharpen Substrate Discrimination during Membrane…

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/82_Zhang_ZR_Cell_2013.pdf
    5 Aug 2013: 0.8. 0.6. 0.2. 0. 0 5 10 20 30 50 100. ... activity predicted by the model analyzed at 20 s. See also Figure S6.
  23. MR_LMB

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/MR_LMB.pdf
    11 Jun 2013: 68 (64) Pack. 24 (2) Refined. 32 (20) RF/TF. 22 (17) Pack.
  24. pone.0052401 1..15

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Podosome2012/journal.pone.0052401.pdf
    10 Jan 2013: containing 20 mM HEPES, 200 mM NaCl pH 7.5, 2 mM DTT. ... to be 141000M21cm21. Buffer conditions were 20 mM Tris,. 200mM NaCl, 0.1 mM DTT.
  25. , 130081, published 7 August 20133 2013 Open Biol. ...

    https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Open%20Biol.-2013-TakedaCombined.pdf
    25 Sep 2013: 0 min 5 min 10 min 15 min 20 min 25 min 30 min 35 min. ... valu. e. 100. 0 0 20 40 60 80 100 12050 100 150distance distance.
  26. Making pre+y pictures So how does one go about ...

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/20130611_Cryst_Figures.pdf
    11 Jun 2013: One in twelve Caucasian (8%), one in 20 Asian (5%), and one in 25 African (4%) males are so-‐called "red-‐green" colorblind.
  27. Supplement_Final

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/81_Shao_S_Mol_Cell_2013.pdf
    16 May 2013: 1 mM ATP, 1 mM GTP, 12 mM creatine phosphate, 20 mg/ml creatine kinase),.
  28. Maximum Llikelihood Dice

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/LMB-EP-McCoy.pdf
    21 May 2013: 20 4 20 5. 10 3 10 5 20 4. 10 1 10 5 20 3. ... 20 2 20 5. 123456789. 10. Central limit theorem. The average of many games of dice.
  29. Expression, purifica0on, characteriza0on, and crystalliza0on So how…

    https://www2.mrc-lmb.cam.ac.uk/download/03-protein-expression-crystallization-and-mutagenesis-meindert-lamers/?wpdmdl=18793&refresh=6699321a8417c1721315866
    2 May 2013: Nucleic Acids Res. 1990 Oct 25;18(20):6069-‐74. PubMed PMID: 2235490. OD600. Time. ... Liga-on-‐independent cloning of PCR products (LIC-‐PCR). Nucleic Acids Res. 1990 Oct 25;18(20):6069-‐74.
  30. Making pre+y pictures So how does one go about ...

    https://www2.mrc-lmb.cam.ac.uk/download/14-making-pretty-pictures-of-macromolecules-meindert-lamers/?wpdmdl=18789&refresh=6699321b086301721315867
    11 Jun 2013: One in twelve Caucasian (8%), one in 20 Asian (5%), and one in 25 African (4%) males are so-‐called "red-‐green" colorblind.
  31. Experimental phasing, Pattersons and SHELX Andrea Thorn What is ...

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/thorn_lmb2013_experimental_phasing.pdf
    14 May 2013: 20. 22 '''f. ffa. . sinα|F||F|ccosα|F||F|b|F|a|F||F| ATAT2. A2. T2. lkh .
  32. Expression, purifica0on, characteriza0on, and crystalliza0on So how…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/20130430_Cryst_course.pdf
    2 May 2013: Nucleic Acids Res. 1990 Oct 25;18(20):6069-‐74. PubMed PMID: 2235490. OD600. Time. ... Liga-on-‐independent cloning of PCR products (LIC-‐PCR). Nucleic Acids Res. 1990 Oct 25;18(20):6069-‐74.
  33. Experimental phasing, Pattersons and SHELX Andrea Thorn What is ...

    https://www2.mrc-lmb.cam.ac.uk/download/experimental-phasing-pattersons-and-shelx/?wpdmdl=18797&refresh=6699321a0baa91721315866
    14 May 2013: 20. 22 '''f. ffa. . sinα|F||F|ccosα|F||F|b|F|a|F||F| ATAT2. A2. T2. lkh .
  34. Kevin Cowtan, cowtan@ysbl.york.ac.uk 2012 Automated phase…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/densitymod12-ppt.pdf
    28 May 2013: Slide 19. Slide 20. Slide 21. Slide 22. Slide 23. Slide 24.
  35. Twinning and other pathologies Andrey Lebedev CCP4 OD-­‐structures…

    https://www2.mrc-lmb.cam.ac.uk/download/twinningaandaotherapathologiesa-andreyalebedeva-a/?wpdmdl=18788&refresh=6699321ae4a491721315866
    11 Jun 2013: 04/06/2013 Crystallography Course LMB 20. Trame, C. B. & McKay, D. ... 10. 10 2020. 20. 20 30 40 50. I/σ(I. ). h k l.
  36. Slide 1

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/processing.pdf
    13 May 2013: 0.03Å error in a cell edge of 100Å). 20/44. 20/44. Post-refinement.
  37. Maximum Llikelihood Dice

    https://www2.mrc-lmb.cam.ac.uk/download/08-maximum-likelihood-experimental-phasing-isomorphous-replacement-and-anomalous-scattering-airlie-mccoy/?wpdmdl=18798&refresh=6699321a9c1371721315866
    21 May 2013: 20 4 20 5. 10 3 10 5 20 4. 10 1 10 5 20 3. ... 20 2 20 5. 123456789. 10. Central limit theorem. The average of many games of dice.
  38. Kevin Cowtan, cowtan@ysbl.york.ac.uk 2012 Automated phase…

    https://www2.mrc-lmb.cam.ac.uk/download/automated-phase-improvement-and-model-building-kevin-cowtan-cowtanysbl-york-ac-uk/?wpdmdl=18786&refresh=6699321b2057e1721315867
    28 May 2013: Slide 19. Slide 20. Slide 21. Slide 22. Slide 23. Slide 24.
  39. Expression, purifica0on, characteriza0on, and crystalliza0on So how…

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/03-protein-expression-crystallization-and-mutagenesis-meindert-lamers/?wpdmdl=18793&
    2 May 2013: Nucleic Acids Res. 1990 Oct 25;18(20):6069-‐74. PubMed PMID: 2235490. OD600. Time. ... Liga-on-‐independent cloning of PCR products (LIC-‐PCR). Nucleic Acids Res. 1990 Oct 25;18(20):6069-‐74.
  40. Twinning and other pathologies Andrey Lebedev CCP4 OD-­‐structures…

    https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/pathologies_and_twinning.pdf
    11 Jun 2013: 04/06/2013 Crystallography Course LMB 20. Trame, C. B. & McKay, D. ... 10. 10 2020. 20. 20 30 40 50. I/σ(I. ). h k l.
  41. Slide 1

    https://www2.mrc-lmb.cam.ac.uk/download/integration-and-scaling-harry-powell-mrc-lmb-crystallography-course-10th-may-2013/?wpdmdl=18796&refresh=6699321a23bab1721315866
    13 May 2013: 0.03Å error in a cell edge of 100Å). 20/44. 20/44. Post-refinement.
  42. Making pre+y pictures So how does one go about ...

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/14-making-pretty-pictures-of-macromolecules-meindert-lamers/?wpdmdl=18789&
    11 Jun 2013: One in twelve Caucasian (8%), one in 20 Asian (5%), and one in 25 African (4%) males are so-‐called "red-‐green" colorblind.
  43. MR_LMB

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/molecular-replacement/?wpdmdl=18799&
    11 Jun 2013: 68 (64) Pack. 24 (2) Refined. 32 (20) RF/TF. 22 (17) Pack.
  44. Maximum Llikelihood Dice

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/08-maximum-likelihood-experimental-phasing-isomorphous-replacement-and-anomalous-scattering-airlie-mccoy/?wpdmdl=18798&
    21 May 2013: 20 4 20 5. 10 3 10 5 20 4. 10 1 10 5 20 3. ... 20 2 20 5. 123456789. 10. Central limit theorem. The average of many games of dice.
  45. Experimental phasing, Pattersons and SHELX Andrea Thorn What is ...

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/experimental-phasing-pattersons-and-shelx/?wpdmdl=18797&
    14 May 2013: 20. 22 '''f. ffa. . sinα|F||F|ccosα|F||F|b|F|a|F||F| ATAT2. A2. T2. lkh .
  46. Kevin Cowtan, cowtan@ysbl.york.ac.uk 2012 Automated phase…

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/automated-phase-improvement-and-model-building-kevin-cowtan-cowtanysbl-york-ac-uk/?wpdmdl=18786&
    28 May 2013: Slide 19. Slide 20. Slide 21. Slide 22. Slide 23. Slide 24.
  47. Twinning and other pathologies Andrey Lebedev CCP4 OD-­‐structures…

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/twinningaandaotherapathologiesa-andreyalebedeva-a/?wpdmdl=18788&
    11 Jun 2013: 04/06/2013 Crystallography Course LMB 20. Trame, C. B. & McKay, D. ... 10. 10 2020. 20. 20 30 40 50. I/σ(I. ). h k l.
  48. Slide 1

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/integration-and-scaling-harry-powell-mrc-lmb-crystallography-course-10th-may-2013/?wpdmdl=18796&
    13 May 2013: 0.03Å error in a cell edge of 100Å). 20/44. 20/44. Post-refinement.

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