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Dynamin architecture—from monomer to polymer
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/dynaminreviewCOSBILow2010.pdf21 Oct 2010: Current Opinion in Structural Biology 2010, 20:1–8. 2 Proteins. COSTBI-829; NO. ... DynaminQ1 architecture — from monome. Current Opinion in Structural Biology 2010, 20:1–8. -
LMB continues pioneering work started in CPE - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/lmb-continues-pioneering-work-started-in-cpe/24 Sep 2010: Published on. 24 September, 2010. A pioneering MRC research unit in Cambridge focused on the structure, stability and activity of proteins and the engineering of antibodies is closing after 20 years ... MRC. This has more than covered the cost for -
Nobel Prize winners visit Downing Street - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/nobel-prize-winners-visit-downing-street/20 Jan 2010: Published on. 20 January, 2010. “British winners of the prestigious Nobel Prize have gathered at Downing Street to celebrate their achievements … Guests included recent winner Venkatraman Ramakrishnan, a structural biologist at -
LMB scientist honoured as inspirational young female talent - MRC…
https://www2.mrc-lmb.cam.ac.uk/lmb-scientist-honoured-as-inspirational-young-female-talent/16 Feb 2010: Human (and other) genome projects are probably one of the most significant advances in biological and medicinal science in the past 20 years. -
©20 10 N atur e A mer ica, Inc. ...
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/20081827.pdf2 Aug 2010: p110 )19, rheumatoid arthritis (p110 and p110 )20 and asthma (p110 and p110 )21,22. ... Nat. Med. 11, 507–514 (2005). 20. Rommel, C., Camps, M. & Ji, H. -
Chapter 20 In Vitro Dissection of Protein Translocationinto the ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/62_Sharma_AS_MMB_2010.pdf30 Apr 2010: 20.3). Removal of thedetergent can be accomplished in several ways including sim-. ... Repeat this extensively (20 or moretimes) until all traces of MeOH are removed. -
Molecular basis for membrane remodelling and organization
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/F-BAR_proteins/JMConference/programme.html22 Nov 2010: 17:00 – 17:30 Registration and cocktails. 18:00 – 19:30 Dinner. 19:45 – 20:00 Welcome. ... 20:00 – 21:00 The EMBO Lecture (Plenary) James E Rothman (Fergus F. -
Molecular basis for membrane remodelling and organization
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/F-BAR_proteins/JMConference/speakerprofiles.html21 Nov 2010: Bretou M, Anne C, Darchen F. J Neurosci. 2008 Aug 20;28(34):8470-6. ... Apostolidou M, Jayasinghe SA, Langen R. J Biol Chem. 2008 Jun 20;283(25):17205-10. -
Endocytosis: Curvature proteins direct traffic
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/NRMCB_Fcho.pdf18 Jun 2010: 20 Macmillan Publishers Limited. All rights reserved10. -
tutorial-2.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/tutorial-2.pdf16 May 2010: Withsome experience you should be able to get an R-factor of less than 20% in less than30 minutes. -
A Large Particle Associated with the Perimeter of the ...
https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/jcb82.pdf5 Jul 2010: adjusted to pH 8 with KOH. High salt medium was 400mM KCI, 5 mM MgCl2,20 mM triethanolamine chloride, adjusted to pH 8 with KOH. ... Fixation with glutaraldehyde was avoided when uranyl acetate was used. Electron Microscopy and Image -
Coot: Model-building tools for Molecular Graphics
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/coot-nottingham-jan-2010.pdf7 Jan 2010: Slide 19. Slide 20. Slide 21. Slide 22. Slide 23. Slide 24. -
Bacterial actin MreB assembles in complex with cell shape protein RodZ
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/embo2010RodZMreB.pdf17 Feb 2010: Over the past 20 years,. intensive research has given us a glance into how non-. ... and pellet (P) were analysed on a 10–20% SDS gel,stained with Coomassie. -
Many bacterial plasmids are maintained at low copy number ...
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/nrmicro2425.pdf14 Sep 2010: There is no ParR or parC present. The scale bar represents 20 nm. ... 20 Macmillan Publishers Limited. All rights reserved10. 7. Simpson, A. E., Skurray, R. -
MRC plate poster 18 8 2010 hr
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/WWWrobots/PDF/PresentationsOther/Poster%20Plates.pdf6 Sep 2010: use robot or manually dispense 20 µl of silicon oil (provided) into each well. -
emulator as well as a solid understanding of its ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Traub&Wendland2010.pdf1 Jun 2010: 1), with more than 20 established binding part-ners. AP-2 therefore acts as an organizational scaffold that associates with several partners synchronously. ... Mol. Biol. Cell 20, 4640–4651 (2009).4. Boettner, D. R. et al. -
Features critical for membrane binding revealed by DivIVA crystal…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/emboj201099a.pdf20 May 2010: 1 20 73 125 164. N-terminal domain. C-terminal domain. Figure 1 B. ... ω. Cβ. 10 20 30 40 50 60 70–8–40. 48. Δω. -
tutorial-2.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/tutorial/tutorial-2.pdf16 May 2010: Withsome experience you should be able to get an R-factor of less than 20% in less than30 minutes. -
tutorial.dvi
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/files/tutorial.pdf21 Jan 2010: 20. • You can display the contacts too, as you do this:. – ... Python enabled version only: a dialog with geometric outliers and other in-teresting things (if they exist) detected by Refmac shows up 20. -
Crystal Structures of Bacillus subtilis Lon Protease
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/londumanjmb2010.pdf20 Jul 2010: 2 Crystal Structures of B. subtilis Lon Protease. 20 amino acids are created.3 These discrete functionsare facilitated by the presence of separate modules,which are responsible for substrate recognition, ATPhydrolysis, ... coli Lon6. and then confirmed -
DOI: 10.1126/science.1184429 , 1638 (2010); 327Science et al.Simon…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/20339072.pdf2 Aug 2010: hAtg14/Barkor (19, 20) and, in a separate complex,ultraviolet irradiation resistance–associated gene(UVRAG) (21) and Bax-interacting factor-1 (Bif-1)(22). ... predators (19, 20). Similarly, plant growth strat-egies influence tolerance to herbivory (21, -
73687_Trans
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/emboj201099s2.pdf28 Apr 2010: Overlap starts appox. at the beginning of the coiled coil (around residue 72) and ends around residue 90, hence 20 amino acids overlap. -
201010176 1..6
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/PNAS-2010-Aylett-TubZ.pdf21 Oct 2010: The GTPase domains of Methanococcus jannaschii FtsZ (19)and bovine α-tubulin (20) superimpose well with TubZ, whereastheir C-terminal domains are a little more divergent. ... Nat Struct Mol Biol 11:1243–1250. 20. Löwe J, Li H, Downing KH, Nogales E -
Doc2b Is a High-Affinity Ca2+ Sensor forSpontaneous Neurotransmitter…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/GroffenScience2010.pdf30 Apr 2010: 20. 10. 00 5 1510 20. 20. 10. 00 5 1510 20. ... C2A D218,220NC2A WT. 1. 10. 20. 5. 2. mE. PS. C fr. -
The Acetyltransferase Activity of the Bacterial Toxin YopJ ofYersinia …
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Mittal_JBC2010.pdf4 Oct 2010: The lysate was centrifuged at 250,000 g for 20 min usinga TLA 100.2 rotor in a Beckman benchtop ultracentrifuge. ... The extract was then centrifuged at 20,000 g for 20 min at 4 C in a tabletop microcentrifuge. -
Roles of Amphipathic Helices and the Bin/Amphiphysin/Rvs(BAR) Domain…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Jao_JBC2010.pdf4 Oct 2010: tein was combined with 1.4 mg/ml Folch liposomes and incu-bated at room temperature for 20 min. ... 20). We obtained the followingrelation between immersion depth (d) and : d[Å] 6.3 3.9. -
A positively charged channel within the Smc1/Smc3 hinge required for…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/embosmcjingekurze2010.pdf1 Dec 2010: 0.10. –0.15. –0.20. –0.25. 0. –2. –4. –8. –6. B. Smc1Smc3. ... 8 10 12 14 16 ml. 0. 10. 20. 30. mAU Smc1/Smc3Smc1Smc3. -
Modeling membrane shaping by proteins: Focus on EHD2 and N-BAR domains
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/KozlovEHDs.pdf7 Apr 2010: 18–20]), the BAR domain con-taining proteins [14,21–24], EHD2 [25], the complexes of clathrinwith adaptor and accessory proteins (see for reviews e.g. ... For membrane fission a few protein families have been impli-cated: the dynamin family (see for -
Quality and quantity control at the endoplasmic reticulum
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/65_Hegde_RS_COCB_2010.pdf7 Jun 2010: For example, numerous potentialERAD substrates are not glycosylated [19!], and evenglycoproteins can access degradation pathways indepen-dent of ER-resident lectins [20!]. ... mannose on the C branch of N-glycans.Glycobiology 2010, 20:567-575. -
JFCregg_OGS_finaledit
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/Cregg_thesis.pdf14 Dec 2010: permeable to the cuticle then previously suspected, eliciting effects at 20 μM. -
Protein-driven membrane stresses in fusion and fission
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Kozlov%20Trends%20Biochem%20Sci%202010.pdf20 Nov 2010: Nat. Rev. Mol. Cell Biol. 7, 9–19. 20 Kozlov, M.M. and Chernomordik, L.V. ... Biochim. Biophys. Acta 1793, 20–26. 70 Peters, C. et al. (2004) Mutual control of membrane fission and fusionproteins. -
bst641-09a
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/19614567.pdf2 Aug 2010: The p110βisoform can also signal downstream of GPCRs via associationwith Gβγ ; however, the mode of interaction is not clear [18–20]. ... J. Biol. Chem. 272, 24252–24256. 20 Maier, U., Babich, A. and Nurnberg, B. -
JCB: Article The Rockefeller University Press $30.00J. Cell…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/63_Rane_NS_JCB_2010.pdf16 Feb 2010: d. PrP(A3922) 4.0 10 <2 <2 >700PrP(KH-II)H 3.0 30 10 10–20 60PrP(KH-II)M 0.6 30 10 5–8 470PrP(A117V)H ... 4.0 15 4 5–8 570PrP(AV3) 1–4 35 10 10–20 <60Prl-PrP(AV3)6 4.7 15 <2 2–5 >600Prl-PrP(AV3)10 2.4 15 -
A ribosome-associating factor chaperones tail-anchored membrane…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/66_Mariappan_M_Nature_2010.pdf1 Aug 2010: c. a. 2Recruitment. 4Transfer. 3Capture. 1Synthesis. 60. 50. 40. 30. 20. ... Proc. Natl Acad. Sci. USA 106, 21131–21136 (2009). 20. Suloway, C.
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