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Human Antibodies developed for Treatment of Lupus and Anthrax - MRC…
https://www2.mrc-lmb.cam.ac.uk/human-antibodies-developed-for-treatment-of-lupus-and-anthrax/31 Jul 2009: In a 52-week Phase 3 clinical study announced on July 20, 2009, patients with active systemic lupus erythematosus taking belimumab showed statistically significant improvements in their condition over patients taking -
cell4855sup
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/cell%202009%20dynamin%20supp.pdf20 Nov 2009: S2I, J). In order to avoid overestimation of the resolution, we applied a mask that was dilated by an additional 20 Å around the structure. -
The MORPHEUS protein crystallization screen
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/morpheus%202009.pdf12 Nov 2009: 20% w/v PEG 20 000,40% v/v PEG MME 550. 35 Cordell et al. ... 3 Teo et al. (2006). 20% w/v PEG 4000,40% v/v glycerol. -
DOI: 10.1126/science.1164346 , 509 (2009); 323Science et al.Jeanne…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Salje%20et%20al%20Science%202009.pdf23 Jan 2009: 3E)in line with earlier experiments (10, 20, 21), butthe resolution of these images is limited. ... Biol. 156, 246. (2006).20. G. Ebersbach, D. J. Sherratt, K. Gerdes, Mol. -
Science Magazine
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Salje%20et%20al%20Science%202009%20N&V.pdf23 Jan 2009: 19, 20) (see the figure). The resulting textural. signatures include laminations caused by the. ... Springer, Berlin, 1987), vol. 9,. pp. 1–180. 20. N. Noffke, Earth Sci. -
early in DNA damage response and regulateRAP80 localization. Many ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/MartensSytPap07.pdf16 Oct 2009: trans-SNARE complexes, which have been suggestedto be ordered ringwise around the future fusionsite (20). ... Anestimate of the energy released on going frombuckle to stalk formation is 20 kBT. -
bic296a
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/EberthBJ4170371.pdf24 Jan 2009: Allprotein solutions were prepared in 20 mM Tris/HCl (pH 7.5) bysize-exclusion chromatography. ... 25, 2898–2910. 20 Zimmerberg, J. and McLaughlin, S. (2004) Membrane curvature: how BAR domains bendbilayers. -
Structure of a Bacterial Dynamin-like Protein Lipid Tube Provides a…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/cell%202009%20dynamin.pdf19 Dec 2009: BDLP has low sequence iden-. tity of around 20% relative to eukaryotic dynamins and DLPs,. ... 1.35 mg ml1. Reactions were spun in a TLA100 rotor for 20 min at 98,000. -
ARTICLES ; The structural basis of tail-anchoredmembrane protein…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/61_Mateja_A_Nature_2009.pdf3 Aug 2009: 4b, grey). In this open state, the a-helicalsubdomains are separated by more than 20 Å (Fig. ... and 20% glycerol (selenomet) and flash frozen in liquid nitrogen. Crystals of S. -
Molecular Biology of the CellVol. 19, 5093–5103, December 2008 ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/LynchMBC5093.pdf24 Jan 2009: an average of 15.2 1.5(SE, n 20) fusion events (Figure 2A), confirming previousresults (Lynch et al., 2007). ... kDa), and Syt-null cells express-ing Syt-14W (n 15 for 10 kDa, n 20 for 40kDa, and n 25 for 70 kDa) and expressed asthe mean SE. -
Arginine 383 is a crucial residue in ABCG2 biogenesis
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/56_Polgar_O_BBA_2009.pdf13 Jun 2009: Total RNA (20 μg/lane) from each transfectant was electrophoresed and transferred to anitrocellulose membrane. ... J. Biol. Chem. 279 (2004)19781–19789. [20] C.A. McDevitt, R.F. Collins, M. -
doi:10.1016/j.tibs.2009.03.001
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/58_Chakrabarti_O_TIBS_2009.pdf13 Jun 2009: The utilization of more efficient signalsequences [20,30] should make it possible to reduce CtmPrPgeneration [19]. ... EMBO J. 20, 5383–5391. 30 Levine, C.G. et al. (2005) The efficiency of proteincompartmentalization into the secretory pathway. -
Functional Depletion of Mahogunin by Cytosolically Exposed Prion…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/59_Chakrabarti_O_Cell_2009.pdf13 Jun 2009: generation of CtmPrP (between 5% and 20% of total PrP) cause. ... spanning at least 20-fold), and with aggregates of various sizes. and morphology (unpublished data). -
ppat.1000479 1..19
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/60_Ashok_A_PLoS_Path_2009.pdf20 Jun 2009: broad range (,20-fold), suggesting that the normal biosynthetic,trafficking, and degradation pathways for PrP are not easily. ... species represents a very small proportion of the total PrP. synthesized (,10–20%), its relatively long half-life compared -
ANRV378-BI78-31.tex
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/DohertyMcMahonAnnRevBiochem09.pdf27 Apr 2009: In some cells, the cargocomplement may be rather limited, whereas atsynapses, at least 20 different cargoes of diversefunctions are packaged in the same vesicle withhigh fidelity. ... Epsinfamily proteins, which can link cargo [for ex-ample,
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