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41 - 50 of 56 search results for TALK:PC53 20 |u:www.ubs.admin.cam.ac.uk where 0 match all words and 56 match some words.

  1. Results that match 1 of 2 words

  2. Remodelling of stem cells and niche cells from development and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/remodelling_of_stem_cells_and_niche_cells_from_development_and_regeneration_to_disease_non-technic_redacted.pdf
    30 Apr 2024: PPL number: | Granted: 20 Jun 22 | Amended: 18 Oct 23 | Expires: 20 Jun 27. ... However, as indicated above,. PPL number: | Granted: 20 Jun 22 | Amended: 18 Oct 23 | Expires: 20 Jun 27.

  3. Epigenetic inheritence and the control of developmental and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/epigenetic_inheritance_and_the_control_of_developmental_and_physiological_processes_non-technical_s_redacted.pdf
    30 Apr 2024: For example, Angelman syndrome, an imprinting disorder leading to severe intellectual disability affects 1 in 12,000-1 in 20,000 people worldwide, and Prader-Willi syndrome, another imprinting disorder linked

  4. Potent monoclonal antibodies for biologics discovery (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/potent_monoclonal_antibodies_for_biologics_discovery_non-technical_summary_redacted.pdf
    30 Apr 2024: Lung cancer – 1.8 million new patients/year, Breast cancer - 2.1 million new patients/year), Cardiovascular Metabolic and Renal diseases (which account for 20 million deaths/year), and in Respiratory

  5. The development of novel therapies (including cell and gene based…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_development_of_novel_therapies_including_cell_and_gene_based_approaches_for_parkinsons_and_hu_redacted.pdf
    30 Apr 2024: 1. An estimated 20% of mice of strain NSG will show swelling around the hocks. ... Approximately 20% of all animals are expected to develop a neurodegenerative phenotype reaching moderate severity.

  6. Neuronal circuit mechanisms underlying cognitive memory judgements…

    https://www.ubs.admin.cam.ac.uk/system/files/public/neuronal_circuit_mechanisms_underlying_cognitive_memory_judgements_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:38pm, 25 Apr 2024 Page 6 of 17. too small as they weigh only 20-30 g. ... Mice weigh only 20-30 g, so mice are too small for the implants that can weigh about 10 g.

  7. Understanding the roles of autophagy and related pathways in…

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_the_roles_of_autophagy_and_related_pathways_in_proteinopathies_non-technical_summary_redacted.pdf
    30 Apr 2024: Species and numbers of animals expected to be used. Mice: 20,000. ... We have completed successful studies using sample sizes of approximately 20 animals per treatment group using behavioural approaches to assess disease progression against wild-type or

  8. The diversity of glia in health, development and disease…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_diversity_of_glia_in_health_development_and_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: Sub-threshold: 25%. Mild: 50%. Moderate: 20%. Severe: 5%. What will happen to animals at the end of this project?

  9. Genes and environment at the interface of inflammation, immunity and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/genes_and_environment_at_the_interface_of_inflammation_immunity_and_metabolism_non-technical_summa_redacted.pdf
    30 Apr 2024: Mice: 20,000. Predicted harmsTypical procedures done to animals, for example injections or surgical procedures, includingduration of the experiment and number of procedures. ... Tumours typically develop slowly over many (12-20) weeks. Administration of

  10. Determining mechanisms of tumour development and relapse following…

    https://www.ubs.admin.cam.ac.uk/system/files/public/determining_mechanisms_of_tumour_development_and_relapse_following_treatment_non-technical_summary_redacted.pdf
    29 Apr 2024: Mouse: moderate 20%. Mouse: Mild 80%. What will happen to animals at the end of this project?

  11. Profiling of test agents in rodents in a drug discovery platform

    https://www.ubs.admin.cam.ac.uk/system/files/public/profiling_of_test_agents_in_rodents_in_a_drug_discovery_platform_non-technical_summary_redacted.pdf
    30 Apr 2024: In addition, we expect to run a minimum of 20. PPL number: | Granted: 03 Feb 22 | Amended: 08 Nov 23 | Expires: 03 Feb 27. ... The animal will then be put under brief anaesthesia (typically for 20 minutes, maximum of one hour) in order to take images of

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