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14 May 2024: Minutes. Date Friday, 20/11/2020 Time 1.30pm. To Committee Members At Held virtually using MS Teams.

14 May 2024: asked for clarification on charging. Anything which means the technician is going above and beyond for more than approximately 20 minutes should be charged for but will release a clarification statement

14 May 2024: reported there are 20 desktop computers available and will be distributed on a first come, first serve basis.

14 May 2024: Minutes. Date Friday, 24/07/2020 Time 1.30pm. To Committee Members At Held virtually using MS Teams. Subject AWERB Operations Committee Attendees:. Apologies:. Mentioned within text:. 1. Minutes The minutes from the meeting held on 26th June 2020

14 May 2024: Minutes. Date Friday, 22/05/2020 Time 1.30pm. To Committee Members At Held virtually using MS Teams. Subject AWERB Operations Committee Attendees:. Apologies: Mentioned within text: 1. Minutes The minutes were approved. 2. Matters arising None. 3.

14 May 2024: Minutes. Date Friday, 25/09/2020 Time 1.30pm. To Committee Members At Held virtually using MS Teams. Subject AWERB Operations Committee Attendees:. Apologies:. Mentioned within text:. 1. Minutes The minutes from the meeting held on 24th July 2020

14 May 2024: Minutes. Date Friday, 26/06/2020 Time 1.30pm. To Committee Members At Held virtually using MS Teams. Subject AWERB Operations Committee Attendees:. Apologies:. Mentioned within text: 1. Minutes The minutes from the meeting held on 22nd May 2020 were

14 May 2024: Minutes. Date Friday, 21/02/2020 Time 1.30pm. To Committee Members At Meeting Room, 1st Floor, Greenwich House. Subject AWERB Operations Committee Attendees:. Apologies:. Mentioned within text:. 1. Minutes The minutes were approved after minor

30 Apr 2024: 8. Minutes of the AOC meeting 20/10/23 The minutes were noted.

14 May 2024: Minutes. Date Friday, 24/04/2020 Time 1.30pm. To Committee Members At Held using Microsoft Teams. Subject AWERB Operations Committee Attendees:. Apologies:. Mentioned within text:. 1. Minutes The minutes from the meeting held on Friday 21st February

14 May 2024: Protocols 9, 10 & 20. • Protocols 9, 11, 12, 15, 16.

14 May 2024: 7. Standard condition 18 reports. 20/01/23 There have been 10 SC18 since the last meeting.

14 May 2024: 20 06 2019_sc18 • In section 3.5, what do the numbers in brackets refer to?

14 May 2024: In 2.4 it is noted that “20% of the animals were found dead” – yet none are returned as being anything other than mild in the protocol table 2.1: please

14 May 2024: 7. Standard condition 18 reports. 20 new SC 18 reports submitted since last AWERB 3Rs meeting – [nothing to discuss].

14 May 2024: Virus. have several ongoing maintenance issues will take this forward. are doing an outreach programme and want to bring a group of 20, 13–18-year-olds and two.

14 May 2024: Minutes. Date: Friday, 20/10/2023 Time: 1.30pm To: Committee Members At: Subject: AWERB Operations Committee.

14 May 2024: licence. Page 4 of 4. • Protocol 9 The committee suggest additional wording is added to the adverse effects section where weight loss of up to 20% after arterial cannulation is written.

14 May 2024: 7. Good practice; training and competencies The cut-off date for the next IAT term is the 20 h December.

30 Apr 2024: We estimate that carrying out this work in culture will reduce our anticipated animal usage by roughly 20%. ... We will maintain 20 existing transgenic lines and two wild type lines and generate ten new transgenic lines (80x32 lines=2560 fish).

29 Apr 2024: at day 20 out of 21-day incubation period). The majority of the studies will be ex vivo (after death), i.e. ... it decreases fetal body weight by 20% by the end of the incubation period.

30 Apr 2024: PPL number: | Granted: 20 Apr 23 | Amended: 24 Aug 23 | Expires: 20 Apr 28. ... A retrospective assessment of these aims will be due by 20 October 2028.

30 Apr 2024: Animals that have a loss of body weight of 20% relative to the baseline will be killed by a Schedule 1 method. ... altered bowel movements. Weight loss 10-20% of control animals. 3. Marked increase in body temperature, respiration noisy, comatose OR

30 Apr 2024: The remaining 20% will be neonates (new born pups up to weaning - approx. ... Animals experiencing Moderate severity will be closely monitored for weight loss (to gauge the impact of the abnormal movement on their ability to feed) and will be killed

30 Apr 2024: Mice:. 1) Mild 60%. 2) Sub-threshold 20%. 3) Moderate 20%. What will happen to animals at the end of this project?

30 Apr 2024: Route Daily vol. ml/kg Max. No./day Max. No. of doses. oral gavage 20 ml/kg 2 30. ... intraperitoneal 20 ml/kg 1 30. intravenous 10 ml/kg 1 14. intramuscular 10–50 µl 1 6.

30 Apr 2024: The total number of substance administration through all these different routes will typically be 20 and in rare cases up to 60 over a minimum of 50 days.

30 Apr 2024: We have been running these infection models for the last 20 years and during that time we have generated thousands of data points in wild type mice in normal conditions.

30 Apr 2024: Even with timely dialysis, the death rates in patients with kidney failure vary from 20% to 50% over 24 months. ... The incision will be closed with sutures. The surgical procedure is expected to take approximately 20 minutes.

30 Apr 2024: A retrospective assessment of these aims will be due by 20 January 2029. ... Killed. A retrospective assessment of these predicted harms will be due by 20 January 2029.

30 Apr 2024: This will contribute. PPL number: | Granted: 20 Apr 23 | Expires: 20 Apr 28. ... Under terminal or recoverable anaesthesia, an animal at the. PPL number: | Granted: 20 Apr 23 | Expires: 20 Apr 28.

30 Apr 2024: A minority of mice will undergo surgery aimed to interfere with known neuronal pathways connecting the intestine with the central nervous system performed under general anaethesia and typically lasting 10-20

29 Apr 2024: This will be closely monitored (twice a day or more if necessary) and when it exceeds predefined thresholds of either maximal weight loss of 20% or diarrhoea for 48 hours the ... Mild - 20%. Moderate - 80%. PPL number: | Granted: 29 Sep 22 | Amended: 18

29 Apr 2024: We expect to take forwards about 10% of these (20 candidates) for further immunogenicity and functional studies that will involve approximately 150 mice per candidate vaccine.

29 Apr 2024: dermatitis. For example rheumatoid arthritis, which is an autoimmune disease resulting in painful swollen joints and loss of movement, affected nearly 20 million people worldwide in 2017 (Safiri 2019) with more

30 Apr 2024: 20 minutes for the purposes of imaging (typically 1-2 times in a lifetime). ... This will only be experienced by a minority of mice on the moderate protocols (less than 20%).

30 Apr 2024: Species Severity Percentage. Mouse Mild 80%. Mouse Moderate 20%. Mouse Severe 0%.

30 Apr 2024: The total number of transplants performed also fell, ranging from a 3% decline for pancreas transplants to 20% for lung or heart-lung transplants.

30 Apr 2024: PPL number: | Granted: 20 Jun 22 | Amended: 18 Oct 23 | Expires: 20 Jun 27. ... However, as indicated above,. PPL number: | Granted: 20 Jun 22 | Amended: 18 Oct 23 | Expires: 20 Jun 27.

30 Apr 2024: The maximum number of shocks in an animal's lifetime would be 20, which would allow us to assess the effect of prior trauma on subsequent learning about adverse events.

30 Apr 2024: For example, Angelman syndrome, an imprinting disorder leading to severe intellectual disability affects 1 in 12,000-1 in 20,000 people worldwide, and Prader-Willi syndrome, another imprinting disorder linked

30 Apr 2024: Lung cancer – 1.8 million new patients/year, Breast cancer - 2.1 million new patients/year), Cardiovascular Metabolic and Renal diseases (which account for 20 million deaths/year), and in Respiratory

30 Apr 2024: Downloaded: 9:38pm, 25 Apr 2024 Page 6 of 17. too small as they weigh only 20-30 g. ... Mice weigh only 20-30 g, so mice are too small for the implants that can weigh about 10 g.

30 Apr 2024: 1. An estimated 20% of mice of strain NSG will show swelling around the hocks. ... Approximately 20% of all animals are expected to develop a neurodegenerative phenotype reaching moderate severity.

30 Apr 2024: Species and numbers of animals expected to be used. Mice: 20,000. ... We have completed successful studies using sample sizes of approximately 20 animals per treatment group using behavioural approaches to assess disease progression against wild-type or

30 Apr 2024: Sub-threshold: 25%. Mild: 50%. Moderate: 20%. Severe: 5%. What will happen to animals at the end of this project?

30 Apr 2024: Mice: 20,000. Predicted harmsTypical procedures done to animals, for example injections or surgical procedures, includingduration of the experiment and number of procedures. ... Tumours typically develop slowly over many (12-20) weeks. Administration of

29 Apr 2024: Mouse: moderate 20%. Mouse: Mild 80%. What will happen to animals at the end of this project?

30 Apr 2024: In addition, we expect to run a minimum of 20. PPL number: | Granted: 03 Feb 22 | Amended: 08 Nov 23 | Expires: 03 Feb 27. ... The animal will then be put under brief anaesthesia (typically for 20 minutes, maximum of one hour) in order to take images of

30 Apr 2024: All animals will first receive short, behavioural tests in the home cage that last no more than 20 mins, to determine their trait anxiety. ... Subsequently, having received i or ii, adult or juvenile marmosets will receive drugs peripherally (typically 20