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www-jackson.ch.cam.ac.uk/publications/2002/2002_JACS.pdf15 Sep 2003: For example, the folding of amonomeric form of theλ repressor has been studied by NMRline-shape analysis19 and fluorescence stopped-flow spectros-copy.20 Together with results from protein engineering and ... 98, 7760-7764.(19) Huang, G. S.; Oas, T. G. -
Context-Dependent Nature of Destabilizing Mutations on the Stability…
www-jackson.ch.cam.ac.uk/publications/1998/1998_Biochem_Main.pdf17 Sep 2003: O1)Cδ2 11 Leu 103 (Cδ1), Pro 16 (Cγ, CR, Câ), Gln 20. ... S. W., and Holzman, T. F. (1993)Biochemistry 32, 1920-1927. 20. Michnick, S. -
Exploring knotting mechanisms in protein foldingAnna L. Mallam,…
www-jackson.ch.cam.ac.uk/publications/2008/2008_PNAS_YibK_mutants.pdf8 Dec 2008: AdoHcy, implyingthat the cofactor binding site, and therefore the knotted regionof the protein, becomes only completely structured in thedimeric state of the protein (20). ... 16, 20, and 23. Analysis of urea denaturation profiles was performedas in ref. -
doi:10.1016/j.febslet.2004.04.089
www-jackson.ch.cam.ac.uk/publications/2004/2004_FEBS_Lett_UBQ.pdf23 Aug 2004: amide groups [20]. The presence of intermediate states is often inferred from. ... and Clarke, A.R. (1997). Biochemistry 36, 13396–13405.[20] Gladwin, S.T. and Evans, P.A. -
Stimulation of the Weak ATPase Activity of Human Hsp90 by a Client…
www-jackson.ch.cam.ac.uk/publications/2002/2002_jmb.pdf15 Sep 2003: DNA by DNA gyr-ase B.20 All evidence so far suggests that p23 bindsto this state, thereby stabilising the heterocomplexand, for human Hsp90, inhibiting ATP hydrolysis. ... Biol. Chem. 275, 18054-18060. 20. Wigley, D. B., Davies, G. J., Dodson, E. -
doi:10.1016/j.sbi.2005.07.003
www-jackson.ch.cam.ac.uk/publications/2005/2005_Main_repeatProtein_COSB.pdf26 Aug 2005: b-galactoside [51]. 1KRV [51]. LRR A 20- to 29-residue motif forming a. ... An interestingextension of this work was to select for ANK variants thatfunction, both in vitro and in vivo, as kinase inhibitors[20]. -
200912161 8189..8194
www-jackson.ch.cam.ac.uk/publications/2010/2010_PNAS_Mallam_Rogers_Jackson.pdf10 May 2010: This result can explain the efficient folding reactionof YibK and YbeA observed in vitro (20, 26) and has important. ... Proc Natl Acad Sci USA 106:3119–3124. 20. Mallam AL, Jackson SE (2005) Folding studies on a knotted protein. -
201106261 17939..17944
www-jackson.ch.cam.ac.uk/publications/2011/2011_PNAS_Hsp90_complexes.pdf14 Nov 2011: Favorable binding was howeverobserved after prior binding of Hop to the Hsp90 dimer (KD 20 nM). ... MethodsProtein Purification. Hsp90 and cochaperones were human, expressed inEscherichia coli and purified as previously described (20, 29). -
doi:10.1016/j.jmb.2007.06.065
www-jackson.ch.cam.ac.uk/publications/2007/2007_J_mol_biol_Hsp90_inhibition.pdf8 Feb 2008: A 200 μl sampleof 20 μM DMAG was injected into a 1.4 ml cell containing1 μM wild-type Hsp90. ... Edited by S. Radford. (Received 17 April 2007; received in revised form 20 June 2007; accepted 22 June 2007)Available online 29 June 2007. -
Review R81 How do small single-domain proteins fold?Sophie E ...
www-jackson.ch.cam.ac.uk/publications/1998/1998_FoldDes.pdf11 Sep 2003: 5 7.0 20 704 2.21 0.003 1.30 0.63. ... 1. 0. 1. 2. 3. 4. 5. 8 10 12 14 16 18 20 22.
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