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The life of proteins: the good, the mostly good and the ugly
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/68_Morimoto_RI_NSMB_2011.pdf7 Jan 2011: Systematic biochemical studies also elucidated the mechanism by which Ero1-α oxidizes PDI specifically and efficiently among nearly 20 types of PDI-family member proteins. -
Protein targeting and degradation are coupled for elimination of…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/73_Hessa_T_Nature_2011.pdf14 Jul 2011: 20) in cultured cells and assessed the levels of aco-expressed MLP substrate. ... Chemical crosslinking experiments were essentiallycarried out as described previously4,20. Chilled translation reactions were layered. -
Abstract_Book_HMM_v2
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/conferences/JM_Abstract_Book.pdf15 Sep 2011: Daumke. 16:00 --. 19:30. Registration. 16:00 Coffee break. 16:20 Coffee break. ... du réseau neuronal 10:20-10:50 Coffee break - Pause café. Session II. -
Molecular Biology of the CellVol. 21, 3054 –3069, September ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/RVS161_MBC2010.pdf21 Feb 2011: For spot dilution assays, overnightcultures grown in YPD were serially diluted 20-fold and spotted onto theappropriate plates. ... Rvs161-Rvs167induced membrane tubule structures with a diameter of18 –20 nm in 15% of the synthetic liposomes -
JCB: Article The Rockefeller University Press $30.00J. Cell Biol. ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/J%20Cell%20Biol%202010%20Howes.pdf24 Aug 2011: B) 20–25 cells treated as in A were used to calculate the volume fraction (V(v)). ... Bar, 200 nm. (G) Stereology measurements were captured across 20–25 cells in three independent areas as treated in F. -
Molecular Biology of the CellVol. 21, 4325– 4337, December ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/67_Emerman_AE_MBC_2010.pdf11 Nov 2011: C D. 0. 20. 40. 60. 80. 100. SA-PrPBio. Prl-PrP(G123P)BioPrPBio. PrP(AV3)Bio. ... rPHA. PrPBi. o. PrP2H. A. PrPBi. o. PrP2H. A. cyt-BirA:ER-BirA: - -. - -- -. - -. BirA:[Biotin]:. - - 0 2 5 10 20 50 20 50. -
Volume 22 May 15, 2011 1625 Cytosolic aggregates perturb ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/69_Chakrabarti_O_MBC_2011.pdf11 Nov 2011: In cells containing mCFP-PrP40–231 aggregates, we observed increased in-tracellular accumulation of CRFR1 in 20% of cells (Table 1; exam-ples in Figure 7). ... 6.0% (8/133). n.d. n.d. 20% (25/128). 6.5% (10/155). None n.d. 3.8% (5/129). -
pii:B978-0-12-372568-4.00001-X
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/MartensCTMchapter6.pdf3 May 2011: CHAPTER 6. C2 Domains and Membrane Fusion. Sascha Martens1 and Harvey T. McMahon21 Max F. Perutz Laboratories, University of Vienna, Vienna, Austria2 MRC Laboratory of Molecular Biology, Cambridge, United Kingdom. I. OverviewII. Membrane Fusion. A. -
Molecular mechanism and physiological functions of clathrin-mediated…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/McMahon%20NRMB%202011.pdf19 Jul 2011: These cargo-specific adaptor proteins always bind the core adaptor AP2 (REFS 20,21) (FIG. -
Tail-anchored membrane protein insertion into the endoplasmic…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/77_Hegde_RS_NRMCB_2011.pdf16 Nov 2011: Nature Reviews Molecular Cell Biology, (2011). doi:10.1038/nrm3226
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