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New Scenarios of Protein Folding Can Occur on theRibosome ...
www-vendruscolo.ch.cam.ac.uk/obrien11jacs.pdf20 Nov 2013: New Scenarios of Protein Folding Can Occur on theRibosome. Edward P. O’Brien,† John Christodoulou,‡ Michele Vendruscolo,† andChristopher M. Dobson,†. Department of Chemistry, Lensfield Road, UniVersity of Cambridge,Cambridge CB2 1EW, -
Dynamic binding mode of a Synaptotagmin-1–SNARE complex in solution
www-vendruscolo.ch.cam.ac.uk/brewer2015nsmb.pdf28 Nov 2015: nature structural & molecular biology VOLUME 22 NUMBER 7 JULY 2015 5 5 5. a r t i c l e s. Neurotransmitter release is governed by a sophisticated protein machinery1,2. Central components of this machinery are the SNAREs synaptobrevin, syntaxin-1 -
pnas201213624 132..140
www-vendruscolo.ch.cam.ac.uk/ciryam13pnas.pdf10 Jan 2013: In vivo translation rates can substantially delay thecotranslational folding of the Escherichia colicytosolic proteomePrajwal Ciryama,b, Richard I. Morimotob, Michele Vendruscoloa, Christopher M. Dobsona, and Edward P. O’Briena,1. aDepartment of -
C2PROT070165 536..550
www-vendruscolo.ch.cam.ac.uk/periole2007p.pdf25 Feb 2014: times for 200 ns and the. remaining models simulated. two times for 200 ns. ... They found that up to 200. ns simulations were necessary to discriminate between. -
The amyloid state and its association with protein misfolding diseases
www-vendruscolo.ch.cam.ac.uk/knowles2014nrmcb.pdf16 Jun 2014: ΔG. 0 50 100 150 200. –2.5. –2. –1.5. –1. –0.5. -
acs_bi_bi-2009-01285x 1..13
www-vendruscolo.ch.cam.ac.uk/lendel09b.pdf30 Sep 2009: 200. 9 | h. ttp://. pubs. acs. org. P. ublic. ... Addition ofLac causes changes in the 196-200 nm region of the CDspectrum, similar to those seen with CR but with lower magni-tude (Figure 2d). -
The Amyloid-β Pathway in Alzheimer’s Disease
www-vendruscolo.ch.cam.ac.uk/Hampel-2021-Molecular-Psychiatry.pdf28 Sep 2021: Over 200 mutations involvingthis complex have been observed [34]. PSEN2 mutations are rare,with less than 40 mutations currently identified [31, 35]. -
Cholesterol catalyses Aβ42 aggregation through a heterogeneous…
www-vendruscolo.ch.cam.ac.uk/habchi2018nc.pdf26 May 2018: 0 100 200 300 400. 0.6. 0.8. 1.0. 1.2. 0 10 20 30 40. ... Acce. lerat. ion. Aβ42alone. Aβ42 DMPC:cholesterolvesicles (10% cholesterol). [L]/[P] ratio. 50 200. -
36 March 2015 Physics Today www.physicstoday.org Over the past ...
www-vendruscolo.ch.cam.ac.uk/knowles2015pt.pdf1 Mar 2015: 12.). 200 nm. Figure 1. Amyloid fibrils formed from peptide fragments of transthyretin, a protein associated withseveral misfolding diseases. -
Sequence-based prediction of pH-dependent protein solubility using…
www-vendruscolo.ch.cam.ac.uk/Oeller-2023-BiB.pdf28 Feb 2023: Threespectra were obtained using an Applied Photophysics Chirascanand a High Precision Cell made of quartz (Hellma Analytics, pathlength 1 mm) between 200 and 250 nm with a bandwidth of 1 ... PROSO II-A new methodfor protein solubility prediction. FEBS J
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