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  2. Structure of a cholinergic cell membraneNigel Unwina,1 Edited by ...

    https://www2.mrc-lmb.cam.ac.uk/groups/nu/pdf/pnasS22.pdf
    4 Nov 2022: The broken yellow lines identify the well-documented ribbon of δ subunit-linked receptor dimers(14, 15, 18, 24), one of which is labeled in each leaflet to indicate the subunit ... Biophys. J. 92, 3960–3967 (2007). 24. H. W. Chang, E. Bock, Molecular
  3. The age-old problem of telomere maintenance - MRC Laboratory of…

    https://www2.mrc-lmb.cam.ac.uk/the-age-old-problem-of-telomere-maintenance/
    Thumbnail for The age-old problem of telomere maintenance - MRC Laboratory of Molecular Biology 24 Nov 2022: Published on. 24 November, 2022. Kelly Nguyen, a Group Leader in the LMB’s Structural Studies Division, was awarded the 2022 Eppendorf Award for Young European Investigators earlier this year.
  4. Cryo-EM structures reveal molecular basis of human telomerase…

    https://www2.mrc-lmb.cam.ac.uk/cryo-em-structures-reveal-molecular-basis-of-human-telomerase-recruitment/
    Thumbnail for Cryo-EM structures reveal molecular basis of human telomerase recruitment - MRC Laboratory of Molecular Biology 25 Feb 2022: Kelly Nguyen’s group in the LMB’s Structural Studies Division has determined the molecular basis of how the TPP1 and POT1 components of shelterin recruit human telomerase to telomeres and regulate the enzyme’s activity during genomic
  5. Venki Ramakrishnan appointed to the Order of Merit - MRC Laboratory…

    https://www2.mrc-lmb.cam.ac.uk/venki-ramakrishnan-appointed-to-the-order-of-merit/
    Thumbnail for Venki Ramakrishnan appointed to the Order of Merit - MRC Laboratory of Molecular Biology 14 Nov 2022: Appointments to the Order are in the Sovereign’s personal gift. The Order is restricted to 24 members.
  6. Paul Sigler (1934 - 2000) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/paul-sigler-1934-2000/
    Thumbnail for Paul Sigler (1934 - 2000) - MRC Laboratory of Molecular Biology 2 Nov 2022: Nature, 403, 848 (2000) by Brian Matthews. Cell, 101, 23-24 (2000) by Max Perutz.
  7. Annual LMB student, postdoc and staff prizes awarded - MRC Laboratory …

    https://www2.mrc-lmb.cam.ac.uk/annual-lmb-student-postdoc-and-staff-prizes-awarded/
    Thumbnail for Annual LMB student, postdoc and staff prizes awarded - MRC Laboratory of Molecular Biology 24 Oct 2022: Annual LMB student, postdoc and staff prizes awarded. Published on. 24 October, 2022.
  8. EMBO announces 2023 elections for Young Investigator Programme - MRC…

    https://www2.mrc-lmb.cam.ac.uk/embo-announces-2023-elections-for-young-investigator-programme/
    Thumbnail for EMBO announces 2023 elections for Young Investigator Programme - MRC Laboratory of Molecular Biology 22 Nov 2022: Manuela is now an Assistant Professor at ETH Zurich. LMB’s researchers are among 24 life scientists chosen as Young Investigators who are within their first four years as group leaders
  9. Pathway behind pathogenic mechanism of tuberculosis identified - MRC…

    https://www2.mrc-lmb.cam.ac.uk/pathway-behind-pathogenic-mechanism-of-tuberculosis-identified/
    Thumbnail for Pathway behind pathogenic mechanism of tuberculosis identified - MRC Laboratory of Molecular Biology 24 Jun 2022: Published on. 24 June, 2022. TNF induces mROS specifically in macrophages infected with TB mycobacteria (yellow arrows) but not in uninfected macrophages (white arrowhead) from the same zebrafish larva.
  10. Pi-PEG Screen 1.5 disclaimer

    https://www2.mrc-lmb.cam.ac.uk/screens2/pdf/LMB19.pdf
    28 Sep 2022: 6.45 % 1-23 PEG 600 25.65 % BICINE 75 mM 8.4 PEG 2000 MME 6.45 % 1-24 PEG 1000 22.5 % BICINE 75 mM 8.8 PEG 3000 ... 8 PEG 3000 12.9 % 1-35 PEG 200 24.15 % BICINE 75 mM 8.4 PEG 4000 10.65 % 1-36 PEG 300 21.45 % BICINE 75 mM 8.8
  11. César Milstein Lecture to be given by Uğur Şahin and Özlem Türeci -…

    https://www2.mrc-lmb.cam.ac.uk/cesar-milstein-lecture-to-be-given-by-ugur-sahin-and-ozlem-tureci/
    Thumbnail for César Milstein Lecture to be given by Uğur Şahin and Özlem Türeci - MRC Laboratory of Molecular Biology 19 Jul 2022: He died in Cambridge on 24 March 2002. – Uğur Şahin.
  12. Mammalian clock gene Cryptochrome 1 is crucial to suprachiasmatic…

    https://www2.mrc-lmb.cam.ac.uk/mammalian-clock-gene-cryptochrome-1-is-crucial-to-suprachiasmatic-nucleus-timekeeping/
    Thumbnail for Mammalian clock gene Cryptochrome 1 is crucial to suprachiasmatic nucleus timekeeping - MRC Laboratory of Molecular Biology 31 Aug 2022: These organotypic slices are ideal to investigate circadian rhythms as, when cultured ex vivo, they maintain a robust circadian rhythm over a roughly 24-hour period and in effect serve as
  13. Refactoring the genetic code to create organisms protected by a…

    https://www2.mrc-lmb.cam.ac.uk/refactoring-the-genetic-code-to-create-organisms-protected-by-a-genetic-firewall/
    Thumbnail for Refactoring the genetic code to create organisms protected by a genetic firewall - MRC Laboratory of Molecular Biology 24 Oct 2022: Published on. 24 October, 2022. Refactoring the genetic code to create organisms protected by a genetic firewall.
  14. Robotic crystallisation: LMB plates

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/WWWrobots/robot-nomenclature.html
    27 Sep 2022: Clear Strategy Screen 2 pH 4.5. Molecular Dimensions. MD1-16LMB. 24. Stochastic sampling. ... Clear Strategy Screen 2 pH 5.5. Molecular Dimensions. MD1-16LMB. 24. Stochastic sampling.
  15. Donald Caspar (1927 – 2021) - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/donald-caspar-1927-2021/
    Thumbnail for Donald Caspar (1927 – 2021) - MRC Laboratory of Molecular Biology 5 Jan 2022: Cold Spring Harbor Symposia on Quantitative Biology XXVII: 1-24, 1962. Primary Sidebar.
  16. Tripodi Lab

    https://www2.mrc-lmb.cam.ac.uk/groups/tripodi/feed/
    3 May 2022: https://www2.mrc-lmb.cam.ac.uk/groups/tripodi Space & Motion Tue, 24 Nov 2020 14:35:31 0000 en-GB hourly 1 ... tripodi/2020/11/24/chomsky-and-the-platypus/ https://www2.mrc-lmb.cam.ac.uk/groups/tripodi/2020/11/24/chomsky-and-the-platypus/#respond matt Tue
  17. Pi-PEG Screen 1.5 disclaimer

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/WWWrobots/LMB%20plates/LMB19b-Pi-PEG_Screen_1.5_disclaimer.pdf
    27 Sep 2022: 6.45 % 1-23 PEG 600 25.65 % BICINE 75 mM 8.4 PEG 2000 MME 6.45 % 1-24 PEG 1000 22.5 % BICINE 75 mM 8.8 PEG 3000 ... 8 PEG 3000 12.9 % 1-35 PEG 200 24.15 % BICINE 75 mM 8.4 PEG 4000 10.65 % 1-36 PEG 300 21.45 % BICINE 75 mM 8.8
  18. PNAS202120006_proof

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/pnas%20Lee%202022.pdf
    18 Dec 2022: Edited by James Berger, Johns Hopkins Medical Institute, Baltimore, MD; received November 2, 2021; accepted February 24, 2022. ... However, the molecular basis for this extraordinary motoractivity remains enigmatic, despite a significant number of
  19. Asgard archaea shed light on the evolutionary origins of the…

    https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Hatano%20Nat%20Comms%202022.pdf
    13 Jun 2022: Nature Communications, doi:10.1038/s41467-022-30656-2
  20. Mechanism of signal sequence handover from NAC to SRP on ribosomes…

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Science_2022.pdf
    27 Feb 2022: S15), which suggests thatformation of the SRP•SR complex will displaceNAC from SRP at the ER membrane (22–24).The direct interaction of the UBA domain ofNAC with SRP raises questions ... Adv. 7, eabg0942 (2021).24. K. Kobayashi et al., Science 360,
  21. 9780470015902.a0029223

    https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-content/uploads/sites/32/eLS-review_Greger.pdf
    1 Mar 2022: In contrast to LTP and LTD, whichare usually expressed within one hour, these adaptations requirearound 24–48 h, and therefore occur at much slower timescales.In addition, homeostatic scaling is less
  22. The Function, Structure, and Origins of the ER Membrane Protein…

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/Annual_Rev_Biochem_2022.pdf
    11 Apr 2022: Most membrane proteins contain more than one TMD, either within the same polypeptideor as part of obligate complexes with the TMDs of other membrane proteins (2, 24).
  23. The Biogenesis of Multipass Membrane Proteins

    https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2023/08/CSHL_Persp_2022.pdf
    13 Sep 2022: The Biogenesis of Multipass Membrane Proteins. Luka Smalinskait _e and Ramanujan S. Hegde. MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom. Correspondence: rhegde@mrc-lmb.cam.ac.uk. Multipass membrane proteins contain two or

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